Results 141 to 150 of about 77,670 (298)
The Antiviral Activity of Polyphenols
Molecular Nutrition &Food Research, EarlyView.Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard +5 more
wiley +1 more source
Effects of SARS-CoV-2 on the cardiovascular system: More issues to be addressed
Anatolian Journal of Cardiology, 2020 Yang Liu
doaj +1 more source
Sex Differences in Severity and Mortality Among Patients With COVID-19: Evidence from Pooled Literature Analysis and Insights from Integrated Bioinformatic Analysis [PDF]
arXiv, 2020 Objective: To conduct a meta-analysis of current studies that examined sex differences in severity and mortality in patients with COVID-19, and identify potential mechanisms underpinning these differences. Methods: We performed a systematic review to collate data from observational studies examining associations of sex differences with clinical ...
arxiv
A Novel Angiotensin-Converting Enzyme–Related Carboxypeptidase (ACE2) Converts Angiotensin I to Angiotensin 1-9 [PDF]
, 2000 Mary Donoghue +11 more
openalex +1 more source
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT In this communication, we introduce a new structure‐based affinity predictor for protein–protein complexes. This predictor, dubbed PCANN (Protein Complex Affinity by Neural Network), uses the ESM‐2 language model to encode the information about protein binding interfaces and graph attention network (GAT) to parlay this information into Kd$$ {K}
Olga O. Lebedenko +3 more
wiley +1 more source
Frontiers in Cellular and Infection MicrobiologyBackgroundAberrant activation of the classic renin–angiotensin system (RAS) and intestinal micro dysbiosis adversely affect insulin resistance (IR), dyslipidemia, and other metabolic syndrome markers. However, the action of angiotensin-converting enzyme 2 (ACE2) and gut health in systemic homeostasis vary, and their interaction is not completely ...
Lini Song, Wenyi Ji, Xi Cao
openaire +3 more sources
Regulation of urinary ACE2 in diabetic mice
American Journal of Physiology-Renal Physiology, 2013 Angiotensin-converting enzyme-2 (ACE2) enhances the degradation of ANG II and its expression is altered in diabetic kidneys, but the regulation of this enzyme in the urine is unknown. Urinary ACE2 was studied in the db/db model of type 2 diabetes and stretozotocin (STZ)-induced type 1 diabetes during several physiological and pharmacological ...
Daniel Batlle +6 more
openaire +4 more sources
Angiotensin converting enzyme-2 (ACE2) and its possible roles in hypertension, diabetes and cardiac function [PDF]
, 2003 Fiona J. Warner +4 more
openalex +1 more source
Small Science, EarlyView.Two‐dimensional graphene‐based nanomaterials are of significant interest in biomedical applications due to their unique physicochemical properties. Computational modeling provides useful insights into their structure and interactions with biological systems, aiding the nanoparticle design.
Alexa Kamboukos +2 more
wiley +1 more source
Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism [PDF]
, 2004 Gillian Rice +4 more
openalex +1 more source