Results 11 to 20 of about 93,409 (274)

ACE2 Receptor and Its Isoform Short-ACE2 Are Expressed on Human Spermatozoa [PDF]

International Journal of Molecular Sciences, 2022
Angiotensin-converting enzyme 2 (ACE2) is a protein widely expressed in numerous cell types, with different biological roles mainly related to the renin-angiotensin system. Recently, ACE2 has been in the spotlight due to its involvement in the SARS-CoV-2
Taraschi A., Bernabò Nicola, Ramal-Sanchez Marina, Castellini C., Cimini C., Valbonetti L., Barbonetti A., Barboni B.   +7 more
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Effect of age on human ACE2 and ACE2-expressing alveolar type II cells levels [PDF]

Pediatric Research, 2022
BACKGROUND: Angiotensin-converting enzyme 2 (ACE2) is the receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which causes COVID-19. Viral entry requires ACE2 and transmembrane protease serine 2 (TMPRSS2).
Gironacci, Mariela M., Corradi, Gerardo R., Silva, Mauro G., Corradi, Gerardo Raul, de Matteo, Elena Noemí, de Matteo, Elena, Di Camillo, Norma Alicia, Falcoff, Nora L., Silva, Mauro Gastón, Seguel, Rolando F., Tabaj, Gabriela C., Gironacci, Mariela Mercedes, Di Camillo, Norma, Guman, Gabriela R., Nuñez, Myriam   +14 more
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ACE2-Decorated Virus-Like Particles Effectively Block SARS-CoV-2 Infection

International Journal of Nanomedicine
Canan Bayraktar,1,* Alisan Kayabolen,1,* Arda Odabas,1 Aysegul Durgun,1 Ipek Kok,1 Kenan Sevinc,1 Aroon Supramaniam,2 Adi Idris,2,3 Tugba Bagci-Onder1 1Koç University Research Center for Translational Medicine (KUTTAM), Koç University, Istanbul ...
Bayraktar C, Kayabolen A, Odabas A, Durgun A, Kok I, Sevinc K, Supramaniam A, Idris A, Bagci-Onder T   +8 more
doaj   +4 more sources

Effects of Exercise on ACE2 [PDF]

Obesity, 2020
In addition to obesity, conditions that are typically associated with lower physical activity (higher age, hypertension, diabetes, coronary heart disease, and chronic obstructive pulmonary disease) are associated with worse clinical outcomes from COVID-19 (2) [ ]neither vaccines nor effective and safe pharmacotherapies against the novel severe acute
Klöting, Nora, Ristow, Michael, Blüher, Matthias   +2 more
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Genetic Landscape of the ACE2 Coronavirus Receptor [PDF]

Circulation, 2022
Background: SARS-CoV-2, the causal agent of COVID-19, enters human cells using the ACE2 (angiotensin-converting enzyme 2) protein as a receptor. ACE2 is thus key to the infection and treatment of the coronavirus. ACE2 is highly expressed in the heart and respiratory and gastrointestinal tracts, playing important regulatory ...
Yang Z, Macdonald-Dunlop E, Chen J, Zhai R, Li T, Richmond A, Klarić L, Pirastu N, Ning Z, Zheng C, Wang Y, Huang T, He Y, Guo H, Ying K, Gustafsson S, Prins B, Ramisch A, Dermitzakis ET, Png G, Eriksson N, Haessler J, Hu X, Zanetti D, Boutin T, Hwang SJ, Wheeler E, Pietzner M, Raffield LM, Kalnapenkis A, Peters JE, Viñuela A, Gilly A, Elmståhl S, Dedoussis G, Petrie JR, Polašek O, Folkersen L, Chen Y, Yao C, Võsa U, Pairo-Castineira E, Clohisey S, Bretherick AD, Rawlik K, GenOMICC Consortium†, IMI-DIRECT Consortium†, Esko T, Enroth S, Johansson Å, Gyllensten U, Langenberg C, Levy D, Hayward C, Assimes TL, Kooperberg C, Manichaikul AW, Siegbahn A, Wallentin L, Lind L, Zeggini E, Schwenk JM, Butterworth AS, Michaëlsson K, Pawitan Y, Joshi PK, Baillie JK, Mälarstig A, Reiner AP, Wilson JF, Shen X   +70 more
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Soluble ACE2 Is Filtered into the Urine

Kidney360, 2022
Key Points Combining unique genetic and surgical models, we demonstrate that both renal and systemic sources contribute to angiotensin-converting enzyme 2 (ACE2) detected in the urine in angiotensin II–mediated hypertension.Micropuncture coupled with nanoproteomics confirm detection of ACE2 in ...
Jonathan W. Nelson, David I. Ortiz-Melo, Natalie K. Mattocks, Jacqueline M. Emathinger, Jessica Prescott, Katherine Xu, Robert C. Griffiths, Rumie Wakasaki, Paul D. Piehowski, Michael P. Hutchens, Thomas M. Coffman, Susan B. Gurley   +11 more
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ACE2

, 2023
Official Full Name angiotensin I converting enzyme 2 Background The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin
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Variation in the ACE2 receptor has limited utility for SARS-CoV-2 host prediction [PDF]

, 2022
Transmission of SARS-CoV-2 from humans to other species threatens wildlife conservation and may create novel sources of viral diversity for future zoonotic transmission.
Streicker, Daniel G, Keen, Deborah, Uuriintuya Munkhbayar, Streicker, Daniel G., Daniel G. Streicker, Munkhbayar, Uuriintuya, Roman Biek, Mollentze, Nardus, Biek, Roman, Deborah Keen, Nardus Mollentze, Daniel G Streicker   +11 more
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ACE2 as therapeutic agent

Clinical Science, 2020
Abstract The angiotensin-converting enzyme 2 (ACE2) has emerged as a critical regulator of the renin–angiotensin system (RAS), which plays important roles in cardiovascular homeostasis by regulating vascular tone, fluid and electrolyte balance.
Li, Qiuhong, Grant, Maria B., Richards, Elaine M., Raizada, Mohan K.   +3 more
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ACE2-Fc and ACE2(NN)-Fc thermal stability assessment.

, 2022
(a) Non-reduced Coomassie-stained SDS-page gels of the ACE2-Fc fusion proteins (1.5 μg) in the storage condition (-80°C) and at 4°C and 25°C for 1 and 7 days.
Hang Xie (218360), Alicia M. Matthews (14227586), V. Ashutosh Rao (7635122), Talia Faison (14227595), Thomas G. Biel (3605438), Uriel Ortega-Rodriguez (13527813), Xin Bush (14227592), Tongzhong Ju (52651), Cyrus Agarabi (8896346), Vincent M. Falkowski (14227589)   +9 more
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