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An overview of the gut side of the SARS-CoV-2 infection [PDF]
In late 2019, an outbreak of pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) initiated in Wuhan, Hubei province, China. The major clinical symptoms described for coronavirus disease (COVID-19) include respiratory distress
Bruna Barbosa da Luz +8 more
doaj +1 more source
Are new genome variants detected in SARS-CoV-2 expected considering population dynamics in viruses?
The pandemic COVID-19 is caused by a highly transmissible severe acute respiratory coronavirus 2 (SARS-CoV-2) which showed the highest morbidity and mortality rates among the other coronavirus infections such as SARS-CoV and MERS-CoV.
Ergoren Mahmut Cerkez +2 more
doaj +1 more source
THE MECHANISM OF INFLUENCE OF CORONAVIRUS ON THE HEART
This article discusses the data on the effect of coronovirus on the heart. Information is given on the way of penetration of the virus into the human body and the mechanisms of its harmful effects on the body.
D. Zh. Moldagalieva +4 more
doaj +1 more source
Variation in the ACE2 receptor has limited utility for SARS-CoV-2 host prediction [PDF]
Transmission of SARS-CoV-2 from humans to other species threatens wildlife conservation and may create novel sources of viral diversity for future zoonotic transmission.
Streicker, Daniel G +11 more
core +1 more source
Abstract The angiotensin-converting enzyme 2 (ACE2) has emerged as a critical regulator of the renin–angiotensin system (RAS), which plays important roles in cardiovascular homeostasis by regulating vascular tone, fluid and electrolyte balance.
Li, Qiuhong +3 more
openaire +2 more sources
Bioinformatic Evaluation of the miRNAs Targeting ACE2 Gene in COVID-19 [PDF]
Introduction: Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), which began in late 2019 in Wuhan, China, has become a global epidemic. Angiotensin 2 converting enzyme (ACE2) acts as a receptor for host function to cause acute coronavirus 2 acute ...
Milad Rafat +4 more
doaj +1 more source
ACE2-Fc and ACE2(NN)-Fc thermal stability assessment.
(a) Non-reduced Coomassie-stained SDS-page gels of the ACE2-Fc fusion proteins (1.5 μg) in the storage condition (-80°C) and at 4°C and 25°C for 1 and 7 days.
Hang Xie (218360) +9 more
core +1 more source
Fragment Molecular Orbital Based Interaction Analyses on Complexes Between RBD Variants and ACE2 [PDF]
The spike protein plays an important role in the infection of SARS-CoV-2 to human cells, and the binding affinity of receptor binding domain (RBD) to angiotensin-converting enzyme 2 (ACE2) is of special interest.
Shun, Kitahara +5 more
core +1 more source
Official Full Name angiotensin I converting enzyme 2 Background The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin
openaire +3 more sources
Renin-angiotensin system modulators in COVID-19 patients with hypertension: friend or foe?
Background: ACE2, a component of the non-classic renin-angiotensin system (RAS), acts as a functional receptor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2) spike protein, which enables the entry of the virus into the host cells.
Shakhi Shylesh C.M +3 more
doaj +1 more source

