Results 31 to 40 of about 81,776 (169)

Correlations of gene polymorphisms of angiotensin-converting enzyme 2 with onset and prognosis of hypertrophic cardiomyopathy [PDF]

open access: yesJournal of Medical Biochemistry
Background: To investigate the correlations of the gene polymorphisms of angiotensin-converting enzyme 2 (ACE2) with the onset and prognosis of hypertrophic cardiomyopathy (HCM), so as to provide references for the early prevention and precise treatment ...
Li Sujuan   +7 more
doaj   +1 more source

COVID-19: an updated review

open access: yesИнфекция и иммунитет, 2020
COVID-19 is a zoonotic disease that showed higher levels of transmissibility in humans. Coronavirus has the largest recognized genome (28–33 kb) of a positive-sense single stranded RNA.
F. A. Isihak, M. A. Hamad, N. G. Mustafa
doaj   +1 more source

Review of using saliva for COVID-19 testing

open access: yesScientific Dental Journal, 2022
Saliva is a hypotonic solution of gingival, salivary acini, and exudate sulcus fluid from the oral mucosa. Saliva contains proteins, DNA, RNA, micro-RNA, and metabolites; hence, it can be detected early in viruses, bacteria, as well as systemic diseases.
Jessica Endriyana   +1 more
doaj   +1 more source

Pharmacophore mapping of Angiotensin Converting Enzymes (ACEs): Insight to Binding Site of ACE1 and ACE2

open access: yesBiology, Medicine & Natural Product Chemistry
Angiotensin Converting Enzymes (ACEs) are carboxypeptidase enzymes involved in the renin-angiotensin system (RAS), which catalyze angiotensin I by cleavage of the peptide bond. ACE1 has been known as a target for antihypertensive drugs.
Navista Sri Octa Ujiantari   +1 more
doaj   +1 more source

ACE2 in the renin–angiotensin system

open access: yesClinical Science, 2020
AbstractIn 2020 we are celebrating the 20th anniversary of the angiotensin-converting enzyme 2 (ACE2) discovery. This event was a landmark that shaped the way that we see the renin–angiotensin system (RAS) today. ACE2 is an important molecular hub that connects the RAS classical arm, formed mainly by the octapeptide angiotensin II (Ang II) and its ...
Verano-Braga, Thiago   +4 more
openaire   +2 more sources

Study of Concentration of Angiotensin-Converting Enzyme 2 Receptor Proteins in Different Age-groups and Genders with Reference to Susceptibility toward Severe Acute Respiratory Syndrome Coronavirus 2 [PDF]

open access: yesIndian Journal of Respiratory Care
Aim and background: Angiotensin-Converting Enzyme 2 (ACE2) was the main host cell receptor through which Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) ensured its entry into human cells.
Shareef M Buvvaji   +14 more
doaj   +1 more source

Pharmacologic modulation of ACE2 expression [PDF]

open access: yesCurrent Hypertension Reports, 2008
Angiotensin-converting enzyme 2 (ACE2) is an enzymatically active homologue of angiotensin-converting enzyme that degrades angiotensin I, angiotensin II, and other peptides. Recent studies have shown that under pathologic conditions, ACE2 expression in the kidney is altered. In this review, we briefly summarize recent studies dealing with pharmacologic
Soler, María José   +3 more
openaire   +2 more sources

ACE2 level as a marker of CVD [PDF]

open access: yesNature Reviews Cardiology, 2020
Higher levels of angiotensin-converting enzyme 2 in plasma are associated with a greater risk of major cardiovascular disease events, according to a global, population-based study.
openaire   +2 more sources

Glyceraldehyde-3-Phosphate Dehydrogenase Binds with Spike Protein and Inhibits the Entry of SARS-CoV-2 into Host Cells

open access: yesJournal of Innate Immunity
Introduction: Coronavirus disease 2019 caused by coronavirus-2 (SARS-CoV-2) has emerged as an aggressive viral pandemic. Health care providers confront a challenging task for rapid development of effective strategies to combat this and its long-term ...
Rahul Dilawari   +7 more
doaj   +1 more source

Different Cases of SARS-CoV-2 Infection and Its Impact on Health and Economy with Special Emphasis on Antiviral Drug Targets

open access: yesJournal of Pure and Applied Microbiology, 2020
COVID-19 caused by SARS-CoV-2 has not only issued a pandemic situation but also lead to economic disaster and unprecedented health emergency. Being a close relative of Bat corona-virus, SARS and MERS it’s structural and sequence similarity has abled ...
Hiran Kanti Santra, Debdulal Banerjee
doaj   +1 more source

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