Results 31 to 40 of about 93,409 (274)

ACE2-independent SARS-CoV-2 entry in macrophages.

, 2022
(A-B) Representative ACE2 mRNA expression (A) and flow cytometry profiles showing ACE2 surface expression (B) of HEK293T cells stably expressing ACE2 and primary MDMs from multiple donors.
Sallieu Jalloh (14002696), Sanjay Tyagi (8954), Judith Olejnik (367849), Annuurun Nisa (12862822), Maohua Lei (14002699), Suryaram Gummuluru (246362), Ellen L. Suder (11052948), Sita Ramaswamy (14002702), Yuri Bushkin (33972), Hisashi Akiyama (401595), Jacob Berrigan (11052951), Elke Mühlberger (45516)   +11 more
core   +1 more source

Evaluation of the effect of angiotensin converting enzyme2 in corona pandemic affect female infertility: A review article

Fiyz̤, 2021
Background: Recently in 2019, a novel virus from coronavirus family (Sars-CoV-2) was introduced in China. ACE2 is a zinc metalloprotease played role in the angiotensin system.
Mosleh HR, Mehdizadeh M, Moradi F, Moeinzadeh A, Shabani R   +4 more
doaj  

Resveratrol supplementation reduces ACE2 expression in human adipose tissue

Adipocyte, 2021
Angiotensin converting enzyme-2 (ACE2) is the cell-surface receptor enabling cellular entry of SARS-CoV-2. ACE2 is highly expressed in adipose tissue (AT), rendering AT a potential SARS-CoV-2 reservoir contributing to massive viral spread in COVID-19 ...
Marlies de Ligt, Matthijs K. C. Hesselink, Johanna Jorgensen, Nicole Hoebers, Ellen E. Blaak, Gijs H. Goossens   +5 more
doaj   +1 more source

Angiotensin-converting enzyme 2 activation suppresses pulmonary vascular remodeling by inducing apoptosis through the Hippo signaling pathway in rats with pulmonary arterial hypertension

Clinical and Experimental Hypertension, 2019
Objective: To investigate the effects of angiotensin-converting enzyme 2 (ACE2) activation on pulmonary arterial cell apoptosis during pulmonary vascular remodeling associated with pulmonary arterial hypertension (PAH) and to elucidate potential ...
Daole Yan, Gang Li, Yaozhong Zhang, Yinglong Liu   +3 more
doaj   +1 more source

SARS-CoV-2 and endothelial cell interaction in COVID-19: molecular perspectives

Vascular Biology, 2021
SARS-CoV-2 is the agent responsible for the coronavirus disease (COVID-19), which has been declared a pandemic by the World Health Organization. The clinical evolution of COVID-19 ranges from asymptomatic infection to death.
Roberta Giordo, Panagiotis Paliogiannis, Arduino Aleksander Mangoni, Gianfranco Pintus   +3 more
doaj   +1 more source

ACE2 in the renin–angiotensin system

Clinical Science, 2020
AbstractIn 2020 we are celebrating the 20th anniversary of the angiotensin-converting enzyme 2 (ACE2) discovery. This event was a landmark that shaped the way that we see the renin–angiotensin system (RAS) today. ACE2 is an important molecular hub that connects the RAS classical arm, formed mainly by the octapeptide angiotensin II (Ang II) and its ...
Verano-Braga, Thiago, Martins, Ana Luiza Valle, Motta-Santos, Daisy, Campagnole-Santos, Maria José, Santos, Robson Augusto Souza   +4 more
openaire   +2 more sources

Cessation of Renin-Angiotensin System Antagonists During the SARS-CoV-2 Pandemic – Do We Have the Evidence?

Journal of Interdisciplinary Medicine, 2020
The aim of this review is to provide a short update on whether treatment with angiotensin-converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) has beneficial or harmful effects in patients infected with SARS-CoV-2. Epidemiological
Blîndu Emanuel, Gerculy Renata, Opincariu Diana, Cernica Daniel, Benedek Imre   +4 more
doaj   +1 more source

ACE2 [PDF]

Journal of the American Society of Nephrology, 2006
Abundant, well-accepted evidence demonstrates a complete tissue renin-angiotensin system (RAS) within the kidney that plays many roles in the control of the intrarenal vasculature, as well in the control of glomerular and tubular processes ([1][1]).
openaire   +2 more sources

Growing concerns on male reproductive health amidst COVID-19 pandemic

Journal of Family Medicine and Primary Care, 2022
Blood–testis barrier is body's innate mechanism to defend germ cells by creating a physical and immunological barrier. But some viral infections are known to evade it.
Megha Agrawal, Vikas Kumar, Gyan Vardhan
doaj   +1 more source

COVID-19 clinical implications: the significance of nanomedicine [PDF]

BioImpacts, 2020
COVID-19 pandemic has profoundly affected the lives of humans worldwide. We no longer experience the same quality of life and need to come up with effective solutions to combat the clinical implications.
Jaleh Barar
doaj   +1 more source