Results 1 to 10 of about 190,682 (162)

Angiotensin-converting enzyme 2 in dogs with Dirofilaria immitis [PDF]

Parasites & Vectors, 2023
Background Infection by the canine heartworm, Dirofilaria immitis, causes significant cardiopulmonary disease, with progression impacted by increasing parasite numbers and duration of infection.
Darcy B. Adin, Meaghan Spalla, Heather Walden, Jeff Gruntmeir, Jorge A. Hernandez, Maureen Long   +5 more
doaj   +4 more sources

Angiotensin-Converting Enzyme 2: The First Decade [PDF]

International Journal of Hypertension, 2012
The renin-angiotensin system (RAS) is a critical regulator of hypertension, primarily through the actions of the vasoactive peptide Ang II, which is generated by the action of ...
Nicola E. Clarke, Anthony J. Turner
doaj   +3 more sources

Radiotracers for Molecular Imaging of Angiotensin-Converting Enzyme 2. [PDF]

Int J Mol Sci
Angiotensin-converting enzymes (ACE) are well-known for their roles in both blood pressure regulation via the renin-angiotensin system as well as functions in fertility, immunity, hematopoiesis, and many others. The two main isoforms of ACE include ACE and ACE-2 (ACE2).
Xu W, Langhans SA, Johnson DK, Stauff E, Kandula VVR, Kecskemethy HH, Averill LW, Yue X.   +7 more
europepmc   +3 more sources

Effect of Angiotensin-Converting Enzyme Inhibition and Angiotensin II Receptor Blockers on Cardiac Angiotensin-Converting Enzyme 2 [PDF]

Circulation, 2005
Background— Angiotensin-converting enzyme 2 (ACE2) has emerged as a novel regulator of cardiac function and arterial pressure by converting angiotensin II (Ang II) into the vasodilator and antitrophic heptapeptide, angiotensin-(1–7) [Ang-(1–7)].
Mark Chappell, K Bridget Brosnihan, CARLOS M Ferrario   +2 more
exaly   +3 more sources

Epigallocatechin gallate (EGCG) attenuates severe acute respiratory coronavirus disease 2 (SARS-CoV-2) infection by blocking the interaction of SARS-CoV-2 spike protein receptor-binding domain to human angiotensin-converting enzyme 2.

PLoS ONE, 2022
The outbreak of the coronavirus disease 2019 caused by the severe acute respiratory syndrome coronavirus 2 triggered a global pandemic where control is needed through therapeutic and preventive interventions. This study aims to identify natural compounds
Tomokazu Ohishi, Takayuki Hishiki, Mirza S Baig, Sajjan Rajpoot, Uzma Saqib, Tomohiko Takasaki, Yukihiko Hara   +6 more
doaj   +3 more sources

Purification and Characterization of Porcine Angiotensin Converting Enzyme 2

Shipin gongye ke-ji, 2022
Angiotensin converting enzyme 2 (ACE2) is one of the key enzymes involved in blood pressure regulation. Conventional purification method for ACE2 was complicated and with low efficacy.
Weiwei LIU, Lingjing ZHANG, Mengya JI, Ling WENG, Zhigang ZHANG, Guangming LIU, Minjie CAO   +6 more
doaj   +1 more source

Evaluation of the Association between Multilobar Involvement and ACE Inhibitor Use in SARS-CoV-2 Patients

Haseki Tıp Bülteni, 2023
Aim:Angiotensin-converting enzyme 2 (ACE2) acts not only as an enzyme but also as a thought to be central receptor by which severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) enters host cells.
Dilay Satilmis, Burcu Genc Yavuz, Sahin Colak   +2 more
doaj   +1 more source

Ontogeny of angiotensin-converting enzyme 2 [PDF]

Pediatric Research, 2011
This study examined the temporal expression of angiotensin (Ang)-converting enzyme 2 (ACE2) during renal, heart, lung, and brain organogenesis in the mouse.We demonstrate that kidney ACE2 mRNA levels are low on embryonic day (E) 12.5, increase fourfold during development, and decline in adulthood.
Renfang, Song, Graeme, Preston, Ihor V, Yosypiv   +2 more
openaire   +2 more sources

ANGIOTENSIN CONVERTING ENZYME 2 IN THE KIDNEY [PDF]

Clinical and Experimental Pharmacology and Physiology, 2008
SUMMARYAngiotensin converting enzyme 2 (ACE2) is an important homeostatic component of the renin angiotensin system (RAS). ACE2 both degrades the vasoconstrictor, angiotensin II and generates the potent vasodilator peptide, angiotensin 1–7. These actions counterbalance those of ACE.ACE2 is highly expressed in the healthy kidney, particularly in the ...
A, Koitka, M E, Cooper, M C, Thomas, C, Tikellis   +3 more
openaire   +2 more sources

Identification of the SARS-CoV-2 Entry Receptor ACE2 as a Direct Target for Transcriptional Repression by Miz1

Frontiers in Immunology, 2021
Multiple lines of evidence have demonstrated that cigarette smoke or Chronic Obstructive Pulmonary Disease upregulates angiotensin-converting enzyme 2, the cellular receptor for the entry of the severe acute respiratory syndrome coronavirus 2, which ...
Jing Yang, Edith A. Perez, Changchun Hou, Pin Zhang, Michelle Van Scoyk, Robert A. Winn, Lijun Rong, Jing Liu   +7 more
doaj   +1 more source