Results 21 to 30 of about 190,682 (162)
Inverse association between hypertension treatment and COVID-19 prevalence in Japan
International Journal of Infectious Diseases, 2021 Objectives: Cell entry of SARS-CoV-2 depends on angiotensin-converting enzyme II. Angiotensin-converting enzyme II is homologous with, but acts antagonistically to, angiotensin-converting enzyme and has the critical function of protecting the lungs ...
Masako Kinoshita +4 more
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Pathological Role of Angiotensin II in Severe COVID-19
TH Open, 2020 The activated renin–angiotensin system induces a prothrombotic state resulting from the imbalance between coagulation and fibrinolysis. Angiotensin II is the central effector molecule of the activated renin–angiotensin system and is degraded by the ...
Wolfgang Miesbach
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Angiotensin-Converting Enzyme 2–Independent Action of Presumed Angiotensin-Converting Enzyme 2 Activators [PDF]
Hypertension, 2014 Angiotensin (Ang)-converting enzyme 2 (ACE2) is a key enzyme in the metabolism of Ang II. XNT (1-[(2-dimethylamino)ethylamino]-4-(hydroxymethyl)-7-[(4-methylphenyl) sulfonyl oxy]-9H-xanthene-9-one) and diminazene have been reported to exert various organ-protective effects, which are attributed to the activation of ACE2. To test the effect
Philipp K, Haber +5 more
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Oftalʹmologiâ, 2020 Diabetic retinopathy (DR) is becoming more and more widespread disease. Investigation of local changes of metabolic pathways in the eye improves our knowledge about diabetic retinopathy pathogenesis and provide perspective for the development of new ...
V. V. Neroev +6 more
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Angiotensin converting enzyme 2 (ACE2) - the major receptor for SARS-CoV-2 virus [PDF]
Farmacja Polska, 2021 The renin-angiotensin-aldosterone system (RAS) plays a significant role in the regulation of the water and electrolyte balance. Renin from the kidneys converts angiotensinogen to angiotensin I. Angiotensin converting enzyme (ACE) catalyzes the conversion
Sonia Frankowska +3 more
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Progress of angiotensin converting enzyme 2 in cardiovascular diseases [PDF]
Jichu yixue yu linchuang, 2020 Angiotensin-converting enzyme 2 (ACE2) is the receptor for SARS-CoV and SARS-CoV-2(severe acute respiratory syndrom coronavirus 2) viruses, and it is also one of the main family members of renin-angiotensin-aldosterone system.
JIAO Xiao-lu, QIN Yan-wen
doaj
Thymosin-α1 binds with ACE and downregulates the expression of ACE2 in human respiratory epithelia
Frontiers in Bioscience-Landmark, 2022 Background: Thymosin-α1 has been implicated into the treatment of novel respiratory virus Coronavirus Disease 2019 (COVID-19), but the underlying mechanisms are still disputable.
Yu-Hang Zhang +7 more
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Stimulation of Angiotensin Converting Enzyme 2: A Novel Treatment Strategy for Diabetic Nephropathy
Frontiers in Physiology, 2022 Despite current therapies for diabetic nephropathy, many patients continue to progress to end-stage renal disease requiring renal replacement therapy.
Haru Nomura +2 more
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Brain angiotensin‐converting enzymes: role of angiotensin‐converting enzyme 2 in processing angiotensin II in mice [PDF]
Experimental Physiology, 2008 Angiotensin (Ang)‐converting enzyme 2 (ACE2) metabolizes Ang II to the vasodilatory peptide Ang(1–7), while neprilysin (NEP) generates Ang(1–7) from Ang I. Experiments used novel Surface Enhanced Laser Desorption Ionization‐Time of Flight (SELDI‐TOF) mass spectroscopic (MS) assays to study Ang processing.
Elased, K M +3 more
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Angiotensin-Converting Enzyme 2 [PDF]
Hypertension, 2008 The first reports1,2 of the angiotensin-converting enzyme (ACE) homolog, ACE2, in mid-2000 came almost 50 years after the discovery of ACE and, remarkably, its existence had not been predicted from the known physiology of the renin-angiotensin system (RAS) at the time. There has since been an exponential growth in knowledge of ACE2 functions,3 spanning
openaire +5 more sources