Results 11 to 20 of about 206,964 (305)
Frontiers in Pharmacology, 2020 BackgroundThe importance of dietary potassium in health and disease has been underestimated compared with that placed on dietary sodium. Larger effort has been made on reduction of sodium intake and less on the adequate dietary potassium intake, although
Carlos P. Vio +7 more
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Brain angiotensin‐converting enzymes: role of angiotensin‐converting enzyme 2 in processing angiotensin II in mice [PDF]
Experimental Physiology, 2008 Angiotensin (Ang)‐converting enzyme 2 (ACE2) metabolizes Ang II to the vasodilatory peptide Ang(1–7), while neprilysin (NEP) generates Ang(1–7) from Ang I. Experiments used novel Surface Enhanced Laser Desorption Ionization‐Time of Flight (SELDI‐TOF) mass spectroscopic (MS) assays to study Ang processing.
Elased, K M +3 more
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Frontiers in Immunology, 2021 Multiple lines of evidence have demonstrated that cigarette smoke or Chronic Obstructive Pulmonary Disease upregulates angiotensin-converting enzyme 2, the cellular receptor for the entry of the severe acute respiratory syndrome coronavirus 2, which ...
Jing Yang +7 more
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Angiotensin‐converting enzyme 2 and the kidney [PDF]
Experimental Physiology, 2008 Angiotensin‐converting enzyme (ACE) 2 is a homologue of ACE with enzymatic activity that seems to counterbalance the angiotensin II‐promoting effect of ACE. While ACE promotes angiotensin (Ang) II formation from Ang I, ACE2 degrades Ang II and Ang I.
Maria Jose, Soler +2 more
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Nepalese Medical Journal, 2020 Angiotensin-converting enzyme-2 receptor has been unearthed as a prime site of entry of Severe Acute Respiratory Syndrome Coronavirus 2 owing to its strong affinity towards spike protein of Severe Acute Respiratory Syndrome Coronavirus 2, resulting in ...
Kunal Bikram Shaha +5 more
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Angiotensin II and COVID-19. Secrets of interactions
Российский кардиологический журнал, 2020 The article describes current data on the relationship of renin-angiotensin system and related drugs with the risk of COVID-19 infection and its outcomes.
A. O. Konradi, A. O. Nedoshivin
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Glomerular Localization and Expression of Angiotensin-Converting Enzyme 2 and Angiotensin-Converting Enzyme [PDF]
Journal of the American Society of Nephrology, 2006 Angiotensin-converting enzyme 2 (ACE2) expression has been shown to be altered in renal tubules from diabetic mice. This study examined the localization of ACE and ACE2 within the glomerulus of kidneys from control (db/m) and diabetic (db/db) mice and the effect of chronic pharmacologic ACE2 inhibition. ACE2 co-localized with glomerular epithelial cell
Minghao, Ye +5 more
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Isolation of Bat Sarbecoviruses, Japan
Emerging Infectious Diseases, 2022 Surveillance of bat betacoronaviruses is crucial for understanding their spillover potential. We isolated bat sarbecoviruses from Rhinolophus cornutus bats in multiple locations in Japan. These viruses grew efficiently in cells expressing R.
Shin Murakami +9 more
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Conversion of Aβ43 to Aβ40 by the successive action of angiotensin‐converting enzyme 2 and angiotensin‐converting enzyme [PDF]
Journal of Neuroscience Research, 2014 The longer and neurotoxic species of amyloid‐β protein (Aβ), Aβ42 and Aβ43, contribute to Aβ accumulation in Alzheimer's disease (AD) pathogenesis and are considered to be the primary cause of the disease. In contrast, the predominant secreted form of Aβ, Aβ40, inhibits amyloid deposition and may have neuroprotective effects.
Shuyu, Liu +8 more
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Frontiers in Pharmacology, 2022 Angiotensin-converting enzyme 2 (ACE2) is the established cellular receptor for SARS-CoV-2. However, it is unclear whether ACE1 inhibitors (e.g., lisinopril) or angiotensin receptor blockers (e.g., losartan) alter tissue ACE2 expression.
Steven D. Brooks +3 more
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