Correlations of gene polymorphisms of angiotensin-converting enzyme 2 with onset and prognosis of hypertrophic cardiomyopathy [PDF]
Journal of Medical BiochemistryBackground: To investigate the correlations of the gene polymorphisms of angiotensin-converting enzyme 2 (ACE2) with the onset and prognosis of hypertrophic cardiomyopathy (HCM), so as to provide references for the early prevention and precise treatment ...
Li Sujuan +7 more
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Molecular docking study and mapping the binding site of some antiviral nanobodies against receptor binding domain (RBD) of SARS-COV 2 [PDF]
Nanochemistry Research, 2021 Neutralization ability of some antiviral nanobodies was computed against the receptor binding domain (RBD) of the severe acute respiratory syndrome coronavirus 2 (SARS-COV 2).
zahra pahlavan, Mohammad Hossein Fatemi
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Protease inhibitors targeting coronavirus and filovirus entry. [PDF]
, 2015 In order to gain entry into cells, diverse viruses, including Ebola virus, SARS-coronavirus and the emerging MERS-coronavirus, depend on activation of their envelope glycoproteins by host cell proteases.
Agudelo, Juliet +10 more
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Инфекция и иммунитет, 2020 COVID-19 is a zoonotic disease that showed higher levels of transmissibility in humans. Coronavirus has the largest recognized genome (28–33 kb) of a positive-sense single stranded RNA.
F. A. Isihak, M. A. Hamad, N. G. Mustafa
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Review of using saliva for COVID-19 testing
Scientific Dental Journal, 2022 Saliva is a hypotonic solution of gingival, salivary acini, and exudate sulcus fluid from the oral mucosa. Saliva contains proteins, DNA, RNA, micro-RNA, and metabolites; hence, it can be detected early in viruses, bacteria, as well as systemic diseases.
Jessica Endriyana +1 more
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Distinct regions of the Swi5 and Ace2 transcription factors are required for specific gene activation [PDF]
, 1999 Swi5 and Ace2 are cell cycle-regulated transcription factors that activate expression of early G1-specific genes in Saccharomyces cerevisiae. Swi5 and Ace2 have zinc finger DNA-binding domains that are highly conserved, and the two proteins bind to the ...
McBride, Helen J. +2 more
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Biology, Medicine & Natural Product ChemistryAngiotensin Converting Enzymes (ACEs) are carboxypeptidase enzymes involved in the renin-angiotensin system (RAS), which catalyze angiotensin I by cleavage of the peptide bond. ACE1 has been known as a target for antihypertensive drugs.
Navista Sri Octa Ujiantari +1 more
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Journal of the American Society of Nephrology, 2006 Abundant, well-accepted evidence demonstrates a complete tissue renin-angiotensin system (RAS) within the kidney that plays many roles in the control of the intrarenal vasculature, as well in the control of glomerular and tubular processes ([1][1]).
openaire +2 more sources
Study of Concentration of Angiotensin-Converting Enzyme 2 Receptor Proteins in Different Age-groups and Genders with Reference to Susceptibility toward Severe Acute Respiratory Syndrome Coronavirus 2 [PDF]
Indian Journal of Respiratory CareAim and background: Angiotensin-Converting Enzyme 2 (ACE2) was the main host cell receptor through which Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) ensured its entry into human cells.
Shareef M Buvvaji +14 more
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mRNA Display Design of Fibronectin-based Intrabodies That Detect and Inhibit Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Protein [PDF]
, 2009 The nucleocapsid (N) protein of severe acute respiratory syndrome (SARS) coronavirus plays important roles in both viral replication and modulation of host cell processes.
Amstutz +40 more
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