Results 71 to 80 of about 97,072 (276)

ACE2 level as a marker of CVD [PDF]

Nature Reviews Cardiology, 2020
Higher levels of angiotensin-converting enzyme 2 in plasma are associated with a greater risk of major cardiovascular disease events, according to a global, population-based study.
openaire   +2 more sources

Glyceraldehyde-3-Phosphate Dehydrogenase Binds with Spike Protein and Inhibits the Entry of SARS-CoV-2 into Host Cells

Journal of Innate Immunity
Introduction: Coronavirus disease 2019 caused by coronavirus-2 (SARS-CoV-2) has emerged as an aggressive viral pandemic. Health care providers confront a challenging task for rapid development of effective strategies to combat this and its long-term ...
Rahul Dilawari, Gaurav Kumar Chaubey, Radheshyam Modanwal, Asmita Dhiman, Sharmila Talukdar, Ajay Kumar, Chaaya Iyengar Raje, Manoj Raje   +7 more
doaj   +1 more source

Different Cases of SARS-CoV-2 Infection and Its Impact on Health and Economy with Special Emphasis on Antiviral Drug Targets

Journal of Pure and Applied Microbiology, 2020
COVID-19 caused by SARS-CoV-2 has not only issued a pandemic situation but also lead to economic disaster and unprecedented health emergency. Being a close relative of Bat corona-virus, SARS and MERS it’s structural and sequence similarity has abled ...
Hiran Kanti Santra, Debdulal Banerjee
doaj   +1 more source

Identification of Surface Glycoprotein Mutations of SARS-CoV-2 in Isolated Strains from Iraq

Медицинская иммунология, 2022
Background: The global pandemic of coronavirus disease is a societal, economic, and publichealth crisis that is still underway. The spike glycoprotein of SARS-CoV-2 is one of the primary ingredients for virulence, tissue tropism, and host areas.
Ali A. Dawood, B. I. Jasim, O. Riadh Al-Jalily   +2 more
doaj   +1 more source

Interacting proteins, polymorphisms and the susceptibility of animals to SARS-CoV-2 [PDF]

, 2021
: COVID-19, caused by SARS-CoV-2, is a world-wide problem for the human population. It is known that some animal species, such as mink, can become infected and transmit the virus. However, the susceptibility of most animals is not known.
Hancock, John, John T. Hancock, Ros C. Rouse, Rouse, Ros, Alexander Greenhough, Stone, Emma, Greenhough, Alexander, Emma Stone   +7 more
core   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Glucose metabolism disorders associated with COVID-19: clinical and morphological study

Сахарный диабет, 2023
BACKGROUND. Glucose metabolism disorders (GMD) were detected both in acute and in post-COVID, however, its pathogenic aspects remain unclear.AIM. To analyze the occurrence of GMD in post-COVID patients who have had moderate and severe COVID-19 without ...
T. L. Karonova, A. A. Mikhailova, D. I. Lagutina, O. M. Vorobeva, D. O. Grigoreva, K. A. Sterkhova, V. A. Malko, A. G. Mikheeva, A. T. Chernikova, L. B. Mitrofanova, E. V. Shlyakhto   +10 more
doaj   +1 more source

analysis of ACE2 receptor

, 2023
The ACE2 receptor plays a vital role not only in the SARS-CoV-induced epidemic but also in various other diseases, including cardiovascular diseases and ARDS.
Özgentürk, Nehir Özdemir, Nehir Özdemir Özgentürk, Emre Aktaş, Aktaş, Emre   +3 more
core   +1 more source

A Generative Neuro‐Symbolic AI for Protein Sequence Design

Advanced Science, EarlyView.
We introduce EffieDes, a neuro‐symbolic framework coupling deep learning‐based fitness landscape parameterization with exact automated reasoning. Unlike greedy sampling, EffieDes identifies sequences that globally optimize fitness while satisfying intricate design constraints.
Marianne Defresne, Delphine Dessaux, Samuel Buchet, Lucie Barthe, Liza Ammar‐Khodja, Bessam Azizi, Valentin Durante, Gianluca Cioci, Simon de Givry, Alain Roussel, Luis F. Garcia‐Alles, Thomas Schiex, Sophie Barbe   +12 more
wiley   +1 more source

Epigenetic mechanisms regulating COVID-19 infection

Epigenetics, 2021
Coronavirus disease 2019 (COVID-2019) outbreak originating in December 2019 in Wuhan, China has emerged as a global threat to human health. The highly contagious SARS-CoV-2 infection and transmission presents a diversity of human host and increased ...
Sarantis Chlamydas, Athanasios G. Papavassiliou, Christina Piperi   +2 more
doaj   +1 more source