Results 61 to 70 of about 132,338 (329)

A Case of Novel Coronavirus Disease 19 in a Chronic Hemodialysis Patient Presenting with Gastroenteritis and Developing Severe Pulmonary Disease. [PDF]

, 2020
Novel coronavirus disease 2019 (COVID-19) is a highly infectious, rapidly spreading viral disease with an alarming case fatality rate up to 5%.
Amin, Alpesh N, Chang, Yongen, Cheng, Timmy T, Choi, Grace, Ferrey, Antoney J, Gohil, Shruti, Hanna, Ramy M, Hsieh, Lanny, Huang, Susan S, Ivaturi, Kaushik, Kalantar-Zadeh, Kamyar, Lau, Wei Ling, Lee, Richard A, Nguyen, Lawrence, Park, Elisa, Reddy, Uttam, Rhee, Connie M, Tantisattamo, Ekamol, Tonthat, Sam, Wang, Brian   +19 more
core   +1 more source

A novel mechanism of action for angiotensin-(1-7) via the angiotensin type 1 receptor [PDF]

, 2016
No abstract ...
Nicklin, Stuart A.
core   +1 more source

EZH2-mediated H3K27me3 inhibits ACE2 expression

Biochemical and Biophysical Research Communications, 2020
The outbreak of corona virus disease 2019 (COVID-19) caused by SARS-CoV-2 infection is spreading globally and quickly, leading to emerging health issues. SARS-CoV-2 enters into and infects host cells through its spike glycoprotein recognizing the cell receptor Angiotensin-converting enzyme II (ACE2).
Li, Yuanyuan, Li, Honggang, Zhou, Liquan
openaire   +2 more sources

Glyceraldehyde-3-Phosphate Dehydrogenase Binds with Spike Protein and Inhibits the Entry of SARS-CoV-2 into Host Cells

Journal of Innate Immunity
Introduction: Coronavirus disease 2019 caused by coronavirus-2 (SARS-CoV-2) has emerged as an aggressive viral pandemic. Health care providers confront a challenging task for rapid development of effective strategies to combat this and its long-term ...
Rahul Dilawari, Gaurav Kumar Chaubey, Radheshyam Modanwal, Asmita Dhiman, Sharmila Talukdar, Ajay Kumar, Chaaya Iyengar Raje, Manoj Raje   +7 more
doaj   +1 more source

Different Cases of SARS-CoV-2 Infection and Its Impact on Health and Economy with Special Emphasis on Antiviral Drug Targets

Journal of Pure and Applied Microbiology, 2020
COVID-19 caused by SARS-CoV-2 has not only issued a pandemic situation but also lead to economic disaster and unprecedented health emergency. Being a close relative of Bat corona-virus, SARS and MERS it’s structural and sequence similarity has abled ...
Hiran Kanti Santra, Debdulal Banerjee
doaj   +1 more source

Identification of Surface Glycoprotein Mutations of SARS-CoV-2 in Isolated Strains from Iraq

Медицинская иммунология, 2022
Background: The global pandemic of coronavirus disease is a societal, economic, and publichealth crisis that is still underway. The spike glycoprotein of SARS-CoV-2 is one of the primary ingredients for virulence, tissue tropism, and host areas.
Ali A. Dawood, B. I. Jasim, O. Riadh Al-Jalily   +2 more
doaj   +1 more source

Angiotensin Converting Enzyme (ACE) and ACE2 Bind Integrins and ACE2 Regulates Integrin Signalling

PLoS ONE, 2012
The angiotensin converting enzymes (ACEs) are the key catalytic components of the renin-angiotensin system, mediating precise regulation of blood pressure by counterbalancing the effects of each other. Inhibition of ACE has been shown to improve pathology in cardiovascular disease, whilst ACE2 is cardioprotective in the failing heart.
Clarke, N.E., Fisher, M.J., Porter, K.E., Lambert, D.W., Turner, A.J.   +4 more
openaire   +5 more sources

ACE2 and Diabetes: ACE of ACEs? [PDF]

Diabetes, 2010
The mechanisms involved in the development of diabetes and its complications are complex, with a long list of potential derangements on different pathways (1,2). In this commentary, we discuss angiotensin converting enzyme 2 (ACE2) as a potential participant in the development of both islet β-cell insufficiency early on and in the development of ...
Batlle, Daniel, Jose Soler, Maria, Ye, Minghao   +2 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Glucose metabolism disorders associated with COVID-19: clinical and morphological study

Сахарный диабет, 2023
BACKGROUND. Glucose metabolism disorders (GMD) were detected both in acute and in post-COVID, however, its pathogenic aspects remain unclear.AIM. To analyze the occurrence of GMD in post-COVID patients who have had moderate and severe COVID-19 without ...
T. L. Karonova, A. A. Mikhailova, D. I. Lagutina, O. M. Vorobeva, D. O. Grigoreva, K. A. Sterkhova, V. A. Malko, A. G. Mikheeva, A. T. Chernikova, L. B. Mitrofanova, E. V. Shlyakhto   +10 more
doaj   +1 more source