Results 61 to 70 of about 81,776 (169)

The Use of ACE inhibitor/ARB in SARS-CoV-2 Patients: A Comprehensive Narrative Review

Asian Journal of Medical Sciences, 2020
The three most common comorbidities that are associated with increased mortality in COVID-19 patients are Hypertension, Diabetes, and Cardiovascular disease, Angiotensin-converting enzyme (ACE) inhibitors and Angiotensin II receptor blockers (ARB) are ...
Timotius Ivan Hariyanto , Karunia Valeriani Japar , Vika Damay , Felix Kwenandar , Novia Lauren Sieto , Andree Kurniawan   +5 more
doaj   +1 more source

The Role of the Ocular Tissue in SARS-CoV-2 Transmission

Clinical Ophthalmology, 2020
Michael Peng,1 Jiannong Dai,1 Chenna Kesavulu Sugali,1 Naga Pradeep Rayana,1 Weiming Mao1,2 1Department of Ophthalmology, Eugene & Marilyn Glick Eye Institute, Indiana University School of Medicine, Indianapolis, IN, USA; 2Department of Biochemistry ...
Peng M, Dai J, Sugali CK, Rayana NP, Mao W   +4 more
doaj  

ACE2 diversity in placental mammals reveals the evolutionary strategy of SARS-CoV-2

Genetics and Molecular Biology
The recent emergence of SARS-CoV-2 is responsible for the current pandemic of COVID-19, which uses the human membrane protein ACE2 as a gateway to host-cell infection. We performed a comparative genomic analysis of 70 ACE2 placental mammal orthologues to
Bibiana S.O. Fam, Pedro Vargas-Pinilla, Carlos Eduardo G. Amorim, Vinicius A. Sortica, Maria Cátira Bortolini   +4 more
doaj   +1 more source

Terminal Antennas in ACE2

Radioengineering, 2008
The ACE Network of Excellence was a European Commission funded Network of Excellence, which lasted from 2004 to 2007. One of the activities performed by this Network was in the frame of terminal antennas. In this activity, three aspects were covered in three projects: Small antenna technologies, small terminal antenna technologies and benchmarking of ...
Martinez-Vasquez, M., Serrano, R., Carlsson, J., Skrivervik, A.K.   +3 more
openaire   +3 more sources

ACE2 ACTIVATION PROMOTES ANTITHROMBOTIC ACTIVITY

The FASEB Journal, 2009
Hyperactivity of the axis ACE/AngII/AT1R of the renin‐angiotensin system is associated with occurrence of acute thrombotic event. Recently a novel concept of a counterrugulatory axis, ACE2/Ang‐(1‐7)/Mas, has emerged. We hypothesized that ACE2 would be protective against thrombosis.
Rodrigo A, Fraga-Silva, Brian S, Sorg, Mamta, Wankhede, Casey, Dedeugd, Joo Y, Jun, Matthew B, Baker, Yan, Li, Ronald K, Castellano, Michael J, Katovich, Mohan K, Raizada, Anderson J, Ferreira   +10 more
openaire   +2 more sources

COVID-19 and ACE2 receptor in different tissues: From pathophysiologic function to therapeutic responses [PDF]

Archives of Razi Institute
SARS-CoV-2, the virus responsible for COVID-19, is characterized by its high transmission rate, leading to a global pandemic. Millions of people have lost their lives due to the infection caused by this virus.
Mohammad Karimian, Mohaddeseh Behjati, Amir Hossein Mohammadi   +2 more
doaj   +1 more source

Mutations in ace2 gene modulate cytokine levels and alter immune responses in Mycobacterium tuberculosis and SARS-CoV-2 co-infection: a Cameroonian cohort

Frontiers in Immunology
IntroductionSARS-CoV-2 and Mycobacterium tuberculosis (Mtb) share similarities in their modes of transmission, pathophysiological symptoms, and clinical manifestations.
Mary Ngongang Kameni, Mary Ngongang Kameni, Mary Ngongang Kameni, Eric Berenger Tchoupe, Eric Berenger Tchoupe, Severin Donald Kamdem, Severin Donald Kamdem, Nikhil Bhalla, Jean Paul Assam Assam, Arnaud Njuiget Tepa, Fuh Roger Neba, Ranjan Kumar Nanda, Anthony Afum-Adjei Awuah, Anthony Afum-Adjei Awuah, Anthony Afum-Adjei Awuah, John Humphrey Amuasi, John Humphrey Amuasi, John Humphrey Amuasi, Palmer Masumbe Netongo, Palmer Masumbe Netongo, Palmer Masumbe Netongo   +20 more
doaj   +1 more source

Association Between ACE2 and Lung Diseases

Infection and Drug Resistance
Cheng Su,1,* Cai Li,2,* Xinyi Hu,3,* Jing Wang,1,* Linlin Liu,4,* Xianfeng Zhang,4 Yeqing Tong4 1School of Public Health, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China; 2Infectious Disease ...
Su C, Li C, Hu X, Wang J, Liu L, Zhang X, Tong Y   +6 more
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ACE2-Decorated Virus-Like Particles Effectively Block SARS-CoV-2 Infection

International Journal of Nanomedicine
Canan Bayraktar,1,* Alisan Kayabolen,1,* Arda Odabas,1 Aysegul Durgun,1 Ipek Kok,1 Kenan Sevinc,1 Aroon Supramaniam,2 Adi Idris,2,3 Tugba Bagci-Onder1 1Koç University Research Center for Translational Medicine (KUTTAM), Koç University, Istanbul ...
Bayraktar C, Kayabolen A, Odabas A, Durgun A, Kok I, Sevinc K, Supramaniam A, Idris A, Bagci-Onder T   +8 more
doaj  

Angiotensin Converting Enzyme (ACE) and ACE2 Bind Integrins and ACE2 Regulates Integrin Signalling

PLoS ONE, 2012
The angiotensin converting enzymes (ACEs) are the key catalytic components of the renin-angiotensin system, mediating precise regulation of blood pressure by counterbalancing the effects of each other. Inhibition of ACE has been shown to improve pathology in cardiovascular disease, whilst ACE2 is cardioprotective in the failing heart.
Clarke, N.E., Fisher, M.J., Porter, K.E., Lambert, D.W., Turner, A.J.   +4 more
openaire   +5 more sources