Results 41 to 50 of about 81,776 (169)

Identification of Surface Glycoprotein Mutations of SARS-CoV-2 in Isolated Strains from Iraq

open access: yesМедицинская иммунология, 2022
Background: The global pandemic of coronavirus disease is a societal, economic, and publichealth crisis that is still underway. The spike glycoprotein of SARS-CoV-2 is one of the primary ingredients for virulence, tissue tropism, and host areas.
Ali A. Dawood   +2 more
doaj   +1 more source

Glucose metabolism disorders associated with COVID-19: clinical and morphological study

open access: yesСахарный диабет, 2023
BACKGROUND. Glucose metabolism disorders (GMD) were detected both in acute and in post-COVID, however, its pathogenic aspects remain unclear.AIM. To analyze the occurrence of GMD in post-COVID patients who have had moderate and severe COVID-19 without ...
T. L. Karonova   +10 more
doaj   +1 more source

Epigenetic mechanisms regulating COVID-19 infection

open access: yesEpigenetics, 2021
Coronavirus disease 2019 (COVID-2019) outbreak originating in December 2019 in Wuhan, China has emerged as a global threat to human health. The highly contagious SARS-CoV-2 infection and transmission presents a diversity of human host and increased ...
Sarantis Chlamydas   +2 more
doaj   +1 more source

The Discovery of the ACE2 Gene [PDF]

open access: yesCirculation Research, 2013
The discovery of the ACE2 gene broadened the scope of the regulatory mechanisms that govern the biological effects of the renin–angiotensin system in the cardiovascular system and beyond The late Daniel E. Koshland Jr. (1920–2007), a former editor of Science (1985–1995), characterized scientific discoveries into 3 categories of Charge, Challenge, and
openaire   +2 more sources

ACE2 and Microbiota [PDF]

open access: yesJournal of Cardiovascular Pharmacology, 2015
The health of the cardiovascular and pulmonary systems is inextricably linked to the renin-angiotensin system (RAS). Physiologically speaking, a balance between the vasodeleterious (Angiotensin-converting enzyme [ACE]/Angiotensin II [Ang II]/Ang II type 1 receptor [AT1R]) and vasoprotective (Angiotensin-converting enzyme 2 [ACE2]/Angiotensin-(1-7) [Ang-
Colleen T, Cole-Jeffrey   +4 more
openaire   +2 more sources

Evolutionary Analysis of Mammalian ACE2 and the Key Residues Involved in Binding to the Spike Protein Revealed Potential SARS-CoV-2 Hosts

open access: yesJournal of Medical Microbiology and Infectious Diseases, 2022
Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV- 2) spilled over to humans via wild mammals, entering the host cell using angiotensin-converting enzyme 2 (ACE2) as receptor through Spike (S) protein binding.
Luciano Rodrigo Lopes1   +3 more
doaj   +1 more source

SARS-CoV-2: Emerging Role in the Pathogenesis of Various Thyroid Diseases

open access: yesJournal of Inflammation Research, 2021
Avaniyapuram Kannan Murugan,1 Ali S Alzahrani1,2 1Division of Molecular Endocrinology, Department of Molecular Oncology, King Faisal Specialist Hospital and Research Centre, Riyadh, 11211, Saudi Arabia; 2Department of Medicine, King Faisal Specialist ...
Murugan AK, Alzahrani AS
doaj  

ACE and ACE2 in kidney disease

open access: yesWorld Journal of Nephrology, 2015
Renin angiotensin system (RAS) activation has a significant influence on renal disease progression. The classical angiotensin-converting enzyme (ACE)-angiotensin II (Ang II)-Ang II type 1 (AT1) axis is considered to control the effects of RAS activation on renal disease.
Sonoo, Mizuiri, Yasushi, Ohashi
openaire   +2 more sources

Impact of COVID-19 in field of Dentistry

open access: yesRevista Información Científica, 2023
Introduction: COVID-19 is a disease caused by SARS-CoV-2 virus and transmitted through respiratory track. So, dentists face a great risk working directly in the oral cavity. Objective: systematization of the theoretical references concerning the impact
Karen Estefanny Alvarez-Freire   +3 more
doaj   +1 more source

ACE2, the kidney and the emergence of COVID-19 two decades after ACE2 discovery

open access: yesClinical Science, 2020
Abstract Angiotensin-converting enzyme II (ACE2) is a homologue of angiotensin-converting enzyme discovered in 2000. From the initial discovery, it was recognized that the kidneys were organs very rich on ACE2. Subsequent studies demonstrated the precise localization of ACE2 within the kidney and the importance of this enzyme in the ...
Lores, Enrique   +2 more
openaire   +2 more sources

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