Results 201 to 210 of about 77,670 (298)

Role of the ACE2/angiotensin1–7/Mas axis in the cardiovascular system [PDF]

, 2010
Masaru Iwai, Masatsugu Horiuchi
openalex   +1 more source

T‐Cell‐Dependent Bispecific IgGs Protect Aged Mice From Lethal SARS‐CoV‐2 Infection

Advanced Science, Volume 12, Issue 15, April 17, 2025.
This study describes the development of spike‐targeting T‐cell‐dependent bispecific full‐length human immunoglobulin Gs with enhanced efficacy in the treatment of COVID‐19. The significance of T‐cell‐based immunity during infection is highlighted. These results have significant implications for better clinical effectiveness of therapies for COVID‐19 ...
Wenyan Fu, Wei Zhang, Zhongshuai You, Guangyao Li, Chuqi Wang, Changhai Lei, Jian Zhao, Jin Hou, Shi Hu   +8 more
wiley   +1 more source

Regional dynamics and mechanisms behind SARS-CoV-2 XDV.1 prevalence in Chongqing via genomic surveillance and molecular insights. [PDF]

Virus Res
Yan J, Liu F, Hu S, Pan J, Yan Q, Yao L, Jin H, Chen X, He J.   +8 more
europepmc   +1 more source

Potent Inhibition of Viral Entry and Replication of SARS-CoV by siRNAs Targeting the Genes Encoding the Cellular ACE2 Receptor or the Viral Nucleocapsid Protein

, 2007
Xiaomin Yan, Hong Shen, Yuanming Feng, Jun Wang, Shu Lou, Liang Wang, G Wong, Z. Yang, Hongyu Jiang, Xiaofeng Wu   +9 more
openalex   +1 more source

Comparison of the pathogenicity and neutrophil and monocyte response between SARS‐CoV‐2 prototype and Omicron BA.1 in a lethal mouse model

Animal Models and Experimental Medicine, Volume 8, Issue 4, Page 707-717, April 2025.
We conducted clinical characterization studies and performed virological evaluations on mice infected with SARS‐CoV‐2 prototype and Omicron BA.1 using RT‐PCR, HE and immunohistochemistry staining. We also studied the alterations of neutrophils and monocytes caused by the two strains using complete blood count, immunohistochemistry, and flow cytometry ...
Na Rong, Jing Wu, Binbin Zhao, Wanjun Peng, Hekai Yang, Gengxin Zhang, Dangting Ruan, Xiaohui Wei, Jiangning Liu   +8 more
wiley   +1 more source

The Regulation Role of the Gut-Islets Axis in Diabetes

Diabetes, Metabolic Syndrome and Obesity
Songtao Yang,1 Jie Cao,1 Chuan Sun,2 Li Yuan1 1Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China; 2Department of Emergency Medical, Wuhan ASIA ...
Yang S, Cao J, Sun C, Yuan L
doaj  

Vasoactive Intestinal Peptide (VIP) in COVID-19 Therapy-Shedding of ACE2 and TMPRSS2 via ADAM10. [PDF]

Int J Mol Sci
Gutzler C, Höhne K, Bani D, Kayser G, Fähndrich S, Ambros M, Hug MJ, Rieg S, Falcone V, Müller-Quernheim J, Zissel G, Frye BC.   +11 more
europepmc   +1 more source

Angiotensin II Type II Receptor Deficiency Accelerates the Development of Nephropathy in Type I Diabetes via Oxidative Stress and ACE2 [PDF]

, 2011
Shiao-Ying Chang, Yun‐Wen Chen, Isabelle Chénier, Stella Tran, Shaoling Zhang   +4 more
openalex   +1 more source

FDA-approved drug repurposing screen identifies inhibitors of SARS-CoV-2 pseudovirus entry. [PDF]

Front Pharmacol
Singh M, Shanmukha S, Eldesouki RE, Harraz MM.   +3 more
europepmc   +1 more source

Identification of residues in the receptor-binding domain (RBD) of the spike protein of human coronavirus NL63 that are critical for the RBD–ACE2 receptor interaction

, 2008
Han-Xin Lin, Yan Feng, Gillian Wong, Liping Wang, Bei Li, Xuesen Zhao, Yan Li, Fiona Smaill, Chengsheng Zhang   +8 more
openalex   +1 more source