Results 201 to 210 of about 149,286 (348)

Moderate to Severe Obstructive Sleep Apnea Is a Risk Factor for Severe COVID‐19—A Nationwide Cohort Study

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT The impact of obstructive sleep apnea (OSA) and positive airway pressure (PAP) treatment on COVID‐19 severity is unclear. In this population‐based, nationwide study using multi‐register data, we aimed to assess if OSA is a risk factor for COVID‐19 severity and how adherence to PAP treatment and clinical characteristics affect the risk. Swedish
Mirjam Ljunggren   +7 more
wiley   +1 more source

Binding of SARS-CoV-2/SARS-CoV spike protein with human ACE2 receptor [PDF]

open access: gold, 2021
Rajendra Prasad Koirala   +5 more
openalex   +1 more source

Psychological and Clinical Factors Mediate Post‐COVID‐19 Irritable Bowel Syndrome

open access: yesNeurogastroenterology &Motility, EarlyView.
ABSTRACT Background Exposure to COVID‐19 has been shown previously to be associated with a higher risk for irritable bowel syndrome (IBS). This study aimed to better explain this relationship using mediation analysis. Methods This post hoc analysis of a multicenter cohort study includes 623 patients with and without COVID‐19 infection. All participants
Keren Hod   +68 more
wiley   +1 more source

Molecular changes in agroinfiltrated leaves of Nicotiana benthamiana expressing suppressor of silencing P19 and coronavirus‐like particles

open access: yesPlant Biotechnology Journal, EarlyView.
Summary The production of coronavirus disease 2019 vaccines can be achieved by transient expression of the spike (S) protein of severe acute respiratory syndrome coronavirus 2 in agroinfiltrated leaves of Nicotiana benthamiana. Relying on bacterial vector Agrobacterium tumefaciens, this process is favoured by co‐expression of viral silencing suppressor
Louis‐Philippe Hamel   +9 more
wiley   +1 more source

A Sep10/MED31 Mediátor-alegység specificitása a transzkripció regulációjában = Specificity of the Sep10/MED31 Mediator subunit in the regulation of transcription [PDF]

open access: yes, 2012
Az elmúlt két évtizedben számos új sejtciklus-gént írtunk le. A sep1 és az ace2 transzkripciós faktorokat kódolnak, amelyek számos M-fázis- és citokinezis-gén transzkripciójához kellenek a Schizosaccharomyces pombe-ben.
Sipiczki, Mátyás, Szilágyi, Zsolt
core  

Posttranslational modifications of heterologous proteins expressed in Nicotiana benthamiana

open access: yesPlant Biotechnology Journal, EarlyView.
Summary The success of Nicotiana benthamiana as a workhorse for heterologous protein production is closely linked to its accessibility and tolerance to genetic manipulation, allowing efficient engineering of posttranslational protein modifications (PTMs) that are critical for the function and stability of heterologous proteins.
Kathrin Göritzer   +2 more
wiley   +1 more source

Structural Design and Immunogenicity of a Novel Self‐Adjuvanting Mucosal Vaccine Candidate for SARS‐CoV‐2 Expressed in Plants

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Mucosal vaccination for COVID‐19 to boost preexisting though insufficient systemic and local/mucosal immunity remains an attractive prospect but there are currently no licensed mucosal vaccines against this infection. Here, using a plant expression system, we developed a novel mucosal vaccine platform for respiratory viruses and demonstrated ...
Mi‐Young Kim   +13 more
wiley   +1 more source

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