Results 281 to 290 of about 149,286 (348)

Current Status of Research on Losartan in Tumour Therapy

Journal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.
ABSTRACT Losartan, a widely prescribed antihypertensive agent, has attracted growing interest as a potential adjuvant in cancer therapy due to its affordability, established safety profile and pleiotropic effects. Emerging preclinical evidence demonstrates that losartan can effectively modulate the tumour microenvironment (TME) by inhibiting ...
Han Wang, Shuang Yuan, Hongjing Wang
wiley   +1 more source

Primary cilium and TULP3-dependent ciliary targeting of ACE2 in SARS-CoV-2 tropism. [PDF]

Cell Commun Signal
Du YH, Tung WL, Wu HH, Hong X, Huang AS, Huang R, Zhang Z, Tang QY, Tang BL, Yang XL, de Alwis R, Tan CW, Hor CHH.   +12 more
europepmc   +1 more source

Integrated Mendelian Randomization and Single‐Cell RNA Sequencing Analyses Reveal Lactate Metabolism as a Key Pathway in COVID‐19‐Induced Pulmonary Fibrosis

Canadian Respiratory Journal, Volume 2026, Issue 1, 2026.
Background The COVID‐19 pandemic has led to a variety of long‐term complications, with COVID‐19‐induced idiopathic pulmonary fibrosis (IPF) becoming a major concern. However, the underlying mechanisms, effective therapeutic strategies, and long‐term prognosis of COVID‐19‐related pulmonary fibrosis remain unclear.
Xin Zhang, Liping Jia, Tuersun Yeziya, Shuyan Yang, Miaomiao Chen, Yan Mo, Xia Tong, Lanlan Zhang, Zijing Zhou   +8 more
wiley   +1 more source

Pyrrolopyrimidine derivatives as dual COX-2/ACE2 inhibitors: design, synthesis, and anti-inflammatory evaluation. [PDF]

Front Mol Biosci
Afifi H, Fatahala SS, Abd El-Hameed RH, Mahgoub S, El-Haggar R, Aly O, Gharib AF, Sayed AI, Taha H.   +8 more
europepmc   +1 more source

Neurogenic Appendicopathy in Pediatric Appendectomies During the COVID‐19 Era: A Retrospective Analysis of Histologically Negative Cases

International Journal of Pediatrics, Volume 2026, Issue 1, 2026.
Introduction In approximately 15% of cases undergoing surgery for acute appendicitis (AA), normal findings are observed in the histological examination of the appendix. Neurogenic appendicopathy (NA) is clinically indistinguishable from AA and is relatively less known.
Yavuz Yilmaz, Elif Emel Erten, Merve Meryem Kiran, Duriye Ozer Turkay, Nikhat Kaura   +4 more
wiley   +1 more source

Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

Nature Structural & Molecular Biology, 2020
J. Huo, Audrey Le Bas, R. Ruza, Helen M. E. Duyvesteyn, H. Mikolajek, T. Malinauskas, T. Tan, P. Rijal, M. Dumoux, P. Ward, Jingshan Ren, Daming Zhou, P. J. Harrison, M. Weckener, D. Clare, V. Vogirala, Julika Radecke, L. Moynié, Yuguang Zhao, Javier Gilbert-Jaramillo, Michael L. Knight, J. Tree, K. Buttigieg, N. Coombes, M. Elmore, M. Carroll, L. Carrique, P. Shah, W. James, A. Townsend, D. Stuart, R. Owens, J. Naismith   +32 more
semanticscholar   +1 more source

Natural Fatty Acids as Dual ACE2-Inflammatory Modulators: Integrated Computational Framework for Pandemic Preparedness. [PDF]

Int J Mol Sci
Lituma-González WD, Ballaz S, Verma T, Sasikumar JM, Lakshmanan S.   +4 more
europepmc   +1 more source

Shared genetics and causal association between plasma levels of SARS‐CoV‐2 entry receptor ACE2 and Alzheimer's disease

Yan Zhang, Fang Xu, Tao Wang, Zhifa Han, Hong Shang, Kevin Han, Ping Zhu, Shan Gao, Xiaojie Wang, Yanli Xue, Chen Huang, Yan Chen, Guiyou Liu   +12 more
openalex   +1 more source

Coronavirus Disease 2019 (COVID-19) Binding Mechanism with Human ACE2: A Computational Approach

, 2020
Megha Lone, Baliram Lone
openalex   +1 more source

Droplet-based single-cell pairing for high-throughput interaction mapping of antigen-receptor combinations. [PDF]

Sci Adv
Nan L, Mao T, Chan CWF, Wang B, Han Z, Choi GCG, Wei X, Wong ASL, Shum HC.   +8 more
europepmc   +1 more source