Results 31 to 40 of about 11,223,266 (194)
DNA methylation analysis of the angiotensin converting enzyme (ACE) gene in major depression. [PDF]
, 2012 The angiotensin converting enzyme (ACE) has been repeatedly discussed as susceptibility factor for major depression (MD) and the bi-directional relation between MD and cardiovascular disorders (CVD).
Eisenmenger, Wolfgang +22 more
core +1 more source
ACE-II genotype and I allele predicts ischemic stroke among males in south India
Meta Gene, 2014 Two hundred ischemic stroke patients and 193 age and sex matched healthy controls were studied for the presence of Angiotensin Converting Enzyme Insertion/Deletion (ACE I/D) gene polymorphism. The PCR studies revealed that ACE ‘II’ (OR = 2.055; p = 0.004)
M. Vijayan +6 more
semanticscholar +1 more source
The geographic distribution of the ACE II genotype: a novel finding.
Genetical research, 2007 Angiotensin converting enzyme (ACE) gene polymorphism insertion (I) or deletion (D) has been widely studied in different populations, and linked to various functional effects and associated with common diseases.
Y. Saab, Paul R. Gard, A. Overall
semanticscholar +1 more source
ACE2 localizes to the respiratory cilia and is not increased by ACE inhibitors or ARBs
Nature Communications, 2020 The coronavirus SARS-CoV-2 is the causative agent of the ongoing severe acute respiratory disease pandemic COVID-19. Tissue and cellular tropism is one key to understanding the pathogenesis of SARS-CoV-2.
Ivan T. Lee +38 more
semanticscholar +1 more source
Potential harmful effects of discontinuing ACE-inhibitors and ARBs in COVID-19 patients
eLife, 2020 The discovery of angiotensin converting enzyme-2 (ACE-2) as the receptor for SARS- CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2) has implicated the renin-angiotensin-aldosterone system in acute respiratory distress syndrome (ARDS) and ...
G. Rossi, V. Sanga, M. Barton
semanticscholar +1 more source
The ACE-2 in COVID-19: Foe or Friend?
Hormone and Metabolic Research, 2020 COVID-19 is a rapidly spreading outbreak globally. Emerging evidence demonstrates that older individuals and people with underlying metabolic conditions of diabetes mellitus, hypertension, and hyperlipidemia are at higher risk of morbidity and mortality.
R. Dalan +7 more
semanticscholar +1 more source
Renal Failure, 2017 Background: The renin-angiotensin system (RAS) has significant influences on heart and renal disease progression. Angiotensin converting enzyme (ACE) and angiotensin converting enzyme II (ACE2) are major peptidases of RAS components and play ...
Chung-Wei Yang +7 more
doaj +1 more source
ACE I and ACE II: immunohistochemical study in primary pterygium
Italian Journal of Anatomy and Embryology, 2010 Pterygium is a common conjunctival disorder exhibiting degenerative and hyperplastic changes as well as proliferative, inflammatory features and a rich vasculature.
P. Demurtas +8 more
semanticscholar +1 more source
ACE/ACE2 Ratio: A Key Also in 2019 Coronavirus Disease (Covid-19)?
Frontiers in Medicine, 2020 Angiotensin-converting enzyme 2 (ACE2) is an aminopeptidase that converts Angiotensin (Ang) II into Ang (1-7). Coronavirus uses ACE2 as a cellular receptor to invade target cells.
P. Pagliaro, C. Penna
semanticscholar +1 more source
Tissue-specific expression of transgenic secreted ACE in vasculature can restore normal kidney functions, but not blood pressure, of Ace-/- mice. [PDF]
PLoS ONE, 2014 Angiotensin-converting enzyme (ACE) regulates normal blood pressure and fluid homeostasis through its action in the renin-angiotensin-system (RAS). Ace-/- mice are smaller in size, have low blood pressure and defective kidney structure and functions. All
Saurabh Chattopadhyay +5 more
doaj +1 more source