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Characterization of Bromelain-Soluble Sheepskin (Ovis aries) Proteins and Effect of In Vitro Gastrointestinal Digestion on Angiotensin Converting Enzyme Inhibition Activity. [PDF]

Food Sci Nutr
Putri DPT, Gallego M, Abidin MZ, Fitriyanto NA, Mora L, Toldrá F, Erwanto Y.   +6 more
europepmc   +1 more source

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Purification and Identification of an ACE Inhibitory Peptide from Walnut Protein

Journal of Agricultural and Food Chemistry, 2013
In the present study, a novel angiotensin I-converting enzyme (ACE)-inhibitory peptide, P-2a2, was purified to homogeneity from walnut protein hydrolysate by ultrafiltration, consecutive column chromatography, and high-performance liquid chromatography. The purified peptide was characterized by matrix-assisted laser desorption ionization time-of-flight
Lanwei Zhang, Ming Du, Weili Xu
exaly   +3 more sources

Identification and the molecular mechanism of a novel myosin-derived ACE inhibitory peptide [PDF]

Food & Function, 2018
The objective of this work was to identify a novel ACE inhibitory peptide from myosin using a number of in silico methods.
Zhipeng Yu, Sijia Wu, Wenzhu Zhao, Long Ding, David Shiuan, Feng Chen, Jianrong Li, Jingbo Liu   +7 more
openaire   +3 more sources

Preparation and antagonistic effect of ACE inhibitory peptide from cashew

Journal of the Science of Food and Agriculture, 2019
AbstractBACKGROUNDAngiotensin‐converting enzyme (ACE) inhibitory peptides were found to alleviate acute hepatitis significantly. In this study, we purified and identified ACE inhibitory peptide from cashew to evaluate its protective role on alcohol‐induced acute hepatitis in mice.RESULTSThe ACE inhibitory peptides were purified by using consecutive ...
Xian Ying Cao
exaly   +3 more sources

Inhibition Strength of Short Peptides Derived from an ACE Inhibitory Peptide

Journal of Agricultural and Food Chemistry, 2011
A series of peptides, derived from an ACE inhibitory peptide (VTVNPYKWLP) found in our previous work, were synthesized. Their half maximal inhibition concentrations (IC(50)) for ACE inhibition have been determined. The effect of amino acid sequence on ACE inhibition was discussed on the basis of IC(50) of the synthetic peptides, and the following ...
Masaaki Terashima
exaly   +3 more sources

A novel ACE inhibitory peptide isolated from Acaudina molpadioidea hydrolysate

Peptides, 2009
Body wall protein from the sea cucumber (Acaudina molpadioidea) was hydrolyzed sequentially with bromelain and alcalase. The hydrolysate was fractionated into two ranges of molecular weight (PH-I, >2 kDa; PH-II,
Shiyuan Dong, Yuan-Hui Zhao, Zunying Liu   +2 more
exaly   +3 more sources

Egg-derived bioactive peptides with ACE-inhibitory properties: a literature update [PDF]

Food & Function, 2017
Egg proteins contain a wide set of peptide sequences which have an impact on cardiovascular health.
Charlotte Grootaert, Bea Matthijs, Stefan Voorspoels, Sam Possemiers, Guy Smagghe, John Van Camp   +5 more
openaire   +3 more sources

Identification of pro-drug type ACE inhibitory peptide sourced from porcine myosin B: Evaluation of its antihypertensive effects in vivo [PDF]

Food Chemistry, 2009
This study aimed to identify a novel angiotensin 1-converting enzyme (ACE) inhibitory peptide from porcine skeletal myosin B. Proteins were hydrolyzed with pepsin and the hydrolysates were then subjected to various types of chromatography to isolate the ...
Michio Muguruma, Masugi Maruyama, S Kawahara   +2 more
exaly   +2 more sources

Antihypertensive activity of orally consumed ACE-I inhibitory peptides

Critical Reviews in Food Science and Nutrition, 2021
Food proteins are sources for ACE-I inhibitory peptides that can be extracted by enzymatic hydrolysis exhibiting anti-hypertensive activity. However, these peptides are prone to further degradation by gastrointestinal enzymes during oral consumption. Bio-activity of these peptides is dependent on the resultant peptide post gastrointestinal digestion ...
Nishithkumar, Jogi, Undiganalu Gangadharappa, Yathisha, Ishani, Bhat, Bangera Sheshappa, Mamatha   +3 more
openaire   +2 more sources

Identification of antioxidant and ACE‐inhibitory peptides in fermented milk

Journal of the Science of Food and Agriculture, 2005
AbstractThe angiotensin‐converting enzyme (ACE)‐inhibitory activity and antioxidant properties of a commercial fermented milk from Europe were evaluated. This dairy product showed moderate ACE‐inhibitory activity and ABTS•+ radical‐scavenging capacity.
Hernández-Ledesma, Blanca, Miralles, Beatriz, Amigo, Lourdes, Ramos González, María Mercedes, Recio, Isidra   +4 more
openaire   +2 more sources