Research Progress on the Mechanism of Action of Food-Derived ACE-Inhibitory Peptides [PDF]
LifeHypertension is a major pathogenic contributor to cardiovascular diseases, primarily mediated through activation of the angiotensin-converting enzyme (ACE) system.
Ting Li +6 more
doaj +6 more sources
Characterization of ACE Inhibitory Peptides Prepared from Pyropia pseudolinearis Protein [PDF]
Marine Drugs, 2021 More than 7000 red algae species have been classified. Although most of them are underused, they are a protein-rich marine resource. The hydrolysates of red algal proteins are good candidates for the inhibition of the angiotensin-I-converting enzyme (ACE)
Yuya Kumagai +7 more
doaj +8 more sources
Revealing the Sequence Characteristics and Molecular Mechanisms of ACE Inhibitory Peptides by Comprehensive Characterization of 160,000 Tetrapeptides [PDF]
Foods, 2023 Chronic diseases, such as hypertension, cause great harm to human health. Conventional drugs have promising therapeutic effects, but also cause significant side effects.
Mingzhe Ma +7 more
doaj +4 more sources
Angiotensin-I-Converting Enzyme (ACE)-Inhibitory Peptides from Plants. [PDF]
Nutrients, 2017 Hypertension is an important factor in cardiovascular diseases. Angiotensin-I-converting enzyme (ACE) inhibitors like synthetic drugs are widely used to control hypertension. ACE-inhibitory peptides from food origins could be a good alternative to synthetic drugs. A number of plant-based peptides have been investigated for their potential ACE inhibitor
Daskaya-Dikmen C +4 more
europepmc +7 more sources
Preparation and Identification of ACE Inhibitory Peptides from the Marine Macroalga Ulva intestinalis [PDF]
Marine Drugs, 2019 Angiotensin I-converting enzyme (ACE) inhibitory peptides derived from seaweed represent a potential source of new antihypertensive. The aim of this study was to isolate and purify ACE inhibitory peptides (ACEIPs) from the protein hydrolysate of the ...
Siqi Sun +5 more
doaj +4 more sources
Three Novel ACE Inhibitory Peptides Isolated From Ginkgo biloba Seeds: Purification, Inhibitory Kinetic and Mechanism [PDF]
Frontiers in Pharmacology, 2019 Alcalase, dispase, trypsin, and flavourzyme were used to hydrolyze the extracted Ginkgo biloba seeds protein isolate (GPI). The Ginkgo protein hydrolyzates (GPHs) with the maximum degree of hydrolysis (DH) and ACE inhibitory activity were selected, and ...
Fei-Fei Ma +7 more
doaj +5 more sources
Food Science and Human Wellness, 2022 The understanding of the structural requirements and the intermolecular-interaction mechanism are important for discovering potent angiotensin-converting enzyme (ACE) inhibitory peptides.
Biying Zhang +5 more
doaj +3 more sources
The stability of antioxidant and ACE-inhibitory peptides as influenced by peptide sequences
LWT - Food Science and Technology, 2020 Abstract As the structural characteristics of peptides affect their functional properties, they are an important factor for peptide stability. The stability characteristic was investigated in two groups of synthetic peptides, analogues of VLSTSFPPK (VL-9). The latter was previously purified from Kluyveromyces marxianus protein hydrolysate.
Mahta Mirzaei +2 more
exaly +2 more sources
Two novel ACE inhibitory peptides isolated from longan seeds: purification, inhibitory kinetics and mechanisms. [PDF]
RSC Adv, 2020 The isolation and subsequent identification of the two novel ACE-inhibitory peptides, ETSGMKPTEL, and ISSMGILVCL from the longan seeds were achieved. The inhibition mechanism was investigated by molecular docking.
Nuchprapha A +7 more
europepmc +4 more sources
ACE inhibitory peptides in standard and fermented deer velvet: an in silico and in vitro investigation. [PDF]
BMC Complement Altern Med, 2019 Abstract Background The use of deer velvet antler (DVA) as a potent traditional medicine ingredient goes back for over 2000 years in Asia. Increasingly, though, DVA is being included as a high protein functional food ingredient in convenient, ready to consume products in Korea and China.
Haines SR +5 more
europepmc +5 more sources