Results 241 to 250 of about 16,784 (281)

Lactokinins: Whey protein-derived ACE inhibitory peptides

Nahrung/Food, 1999
Angiotensin-I-converting enzyme (ACE) has been classically associated with the renin-angiotensin system which regulates peripheral blood pressure. Peptides derived from the major whey proteins, i.e. alpha-lactalbumin (alpha-la) and beta-lactoglobulin (beta-lg) in addition to bovine serum albumin (BSA), inhibit ACE.
R J, FitzGerald, H, Meisel
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ACE Inhibitory Peptides Derived from Aquatic Protein

Current Protein & Peptide Science, 2013
Among bioactive peptides derived from aquatic protein, those with ACE inhibitory activity are receiving special attention. This paper presented an overview of ACE inhibitory peptides derived from aquatic proteins, and the peptide sources were listed.
Lin, Lin, Shun, Lv, Xiaorong, Zhang, Jianfeng, Lu, Yingwang, Ye, Shaotong, Jiang   +5 more
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Identification of a novel ACE-inhibitory peptide from casein and evaluation of the inhibitory mechanisms

Food Chemistry, 2018
Various bioactive peptides are continuously being identified from casein hydrolysates. In this work, a novel angiotensin I-converting enzyme (ACE)-inhibitory (ACEI) peptide, NMAINPSKENLCSTFCK, derived from the αs2-casein fragment residues 25-41, was screened and identified by UPLC-ESI-Q-TOF-MS/MS from tryptic casein hydrolysate.
Maolin, Tu, Cong, Wang, Cheng, Chen, Ruyi, Zhang, Hanxiong, Liu, Weihong, Lu, Lianzhou, Jiang, Ming, Du   +7 more
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Characterization of ACE‐Inhibitory Peptide Associated with Antioxidant and Anticoagulation Properties

Journal of Food Science, 2011
Abstract:  A bioactive peptide Arg–Val–Pro–Ser–Leu (RVPSL) obtained from egg white protein was characterized by LC‐MS and further chemically synthesized by the Fmoc solid phase method and investigated in terms of its angiotensin converting enzyme (ACE)‐inhibitory activity, antioxidant property, and ...
Zhipeng, Yu, Yongguang, Yin, Wenzhu, Zhao, Fei, Wang, Yiding, Yu, Boqun, Liu, Jingbo, Liu, Feng, Chen   +7 more
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Lactoferricin-Related Peptides with Inhibitory Effects on ACE-Dependent Vasoconstriction

Journal of Agricultural and Food Chemistry, 2006
A selection of lactoferricin B (LfcinB)-related peptides with an angiotensin I-converting enzyme (ACE) inhibitory effect have been examined using in vitro and ex vivo functional assays. Peptides that were analyzed included a set of sequence-related antimicrobial hexapeptides previously reported and two representative LfcinB-derived peptides.
José M, Centeno, María C, Burguete, María, Castelló-Ruiz, María, Enrique, Salvador, Vallés, Juan B, Salom, Germán, Torregrosa, José F, Marcos, Enrique, Alborch, Paloma, Manzanares   +9 more
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Screening of ACE-inhibitory peptides from a random peptide-displayed phage library using ACE-coupled liposomes

Journal of Biotechnology, 2007
Angiotensin I converting enzyme (ACE)-inhibitory peptides were screened from a random peptide-displayed phage library using ACE-coupled liposomes. Among four kinds of inhibitory peptides selected by biopanning with two different elution strategies, a peptide (LSTLRSFCA) showed the highest inhibitory activity with an IC(50) value of 3microM.
Yoichi, Kumada, Naoya, Hashimoto, Fida, Hasan, Masaaki, Terashima, Kazuhiro, Nakanishi, Alois, Jungbauer, Shigeo, Katoh   +6 more
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[Synthesis and activity of ACE inhibitory peptides].

Yao xue xue bao = Acta pharmaceutica Sinica, 2012
To find anti-hypertensive lead drug, angiotensin converting enzyme (ACE) inhibitory peptides were synthesized and their effects on inhibiting ACE activity were investigated. ACE inhibitory peptides were synthesized via Fmoc solid-phase synthesis, isolated and purified through reversed phase high-performance liquid chromatography (RP-HPLC), and ...
Jin, Ren, Gang, Cao, Rui-Jie, Zhang, Da-Wei, Li, Ting-Ting, Wei, Chuan-Guang, Qin   +5 more
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Identification of Potent ACE Inhibitory Peptides from Wild Almond Proteins

Journal of Food Science, 2017
Abstract In this study, the production, fractionation, purification and identification of ACE (angiotensin‐I‐converting enzyme) inhibitory peptides from wild almond ( Amygdalus scoparia ) proteins were investigated.
Mozhgan Mirzapour, Karamatollah Rezaei, Miguel Angel Sentandreu   +2 more
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CoMFA and CoMSIA analysis of ACE-inhibitory, antimicrobial and bitter-tasting peptides

European Journal of Medicinal Chemistry, 2014
Comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) were applied to the ACE-inhibitory, antimicrobial, and bitter-tasting peptides. Predictive 3D-QSAR models were established using SYBYL multifit molecular alignment rule over a training set and a test set. The optimum models were all statistically
Shufen, Wu, Wei, Qi, Rongxin, Su, Tonghe, Li, Dan, Lu, Zhimin, He   +5 more
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Optimisation of the hydrolysis of goat milk protein for the production of ACE-inhibitory peptides

Journal of Dairy Research, 2013
Goat milk protein was hydrolysed with subtilisin and trypsin. As input variables, temperature was assayed in the interval 45–70 °C for subtilisin and 30–55 °C for trypsin, while the enzyme-substrate ratio varied from 1 to 5%. The effect of the input variables on the degree of hydrolysis and ACE-inhibitory activity (output variables) was modelled by ...
Francisco Javier, Espejo-Carpio, Raúl, Pérez-Gálvez, Emilia M, Guadix, Antonio, Guadix   +3 more
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