Results 1 to 10 of about 12,514 (200)
Liposome and QS-21 Combined Adjuvant Induces theHumoral and Cellular Responses of Acellular Pertussis Vaccine in a Mice Model [PDF]
The resurgence of pertussis in vaccinated communities may be related to the reduced long-term immunity induced by acellular pertussis vaccines. Therefore, developing improved pertussis vaccine candidates that could induce strong Th1 or Th17 cellular ...
Baifeng Yang +11 more
doaj +2 more sources
Acellular Pertussis Vaccine Effectiveness Over Time. [PDF]
To determine pertussis risk by diphtheria-tetanus-acellular pertussis (DTaP) vaccination status and time since last DTaP dose.Children born at Kaiser Permanente Northern California between 1999 and 2016 were followed from 3 months of age until they tested positive for pertussis; disenrolled from Kaiser Permanente Northern California; received the ...
Zerbo O +5 more
europepmc +4 more sources
Revisiting Whooping Cough: Global Drivers and Implications of Pertussis Resurgence in the Acellular Vaccine Era [PDF]
Background: Whooping cough caused by Bordetella pertussis is re-emerging despite high vaccination coverage, with rising incidence in adolescents and adults in the acellular vaccine (aP) era.
Siheng Zhang, Yan Xu, Ying Xiao
doaj +2 more sources
Bacterial outer membrane vesicles and vaccine applications [PDF]
Vaccines based on outer membrane vesicles (OMV) were developed more than 20 years ago against Neisseria meningitidis serogroup B. These nano-sized structures exhibit remarkable potential for immunomodulation of immune responses and delivery of “self ...
Acevedo, Reinaldo +10 more
core +14 more sources
Despite the high coverage of pertussis vaccines in high-income countries, pertussis resurgence has been reported in recent years, and has stimulated interest in the effects of vaccines and vaccination strategies. Immunoglobulin G (IgG) antibodies against
Zhiying Yin +8 more
doaj +1 more source
Some scientific publications contain data suggesting the “return” or “resurgence” of pertussis. Prevention and elimination of pertussis can only be achieved by extensive immunisation of susceptible populations with a highly effective vaccine.
I. A. Alekseeva +2 more
doaj +1 more source
Introduction Despite high vaccination coverage among children and adolescents, pertussis remains a public health problem, with large outbreaks occurring periodically in the US and other developed countries.Areas covered We examine lessons learned more ...
Ousseny Zerbo +2 more
doaj +1 more source
Pertussis is a vaccine-preventable disease caused by the bacterium Bordetella pertussis. Over the past years, the incidence and mortality of pertussis increased significantly. A possible cause is the switch from whole-cell to acellular pertussis vaccines,
Annieck M. Diks +12 more
doaj +1 more source
Background: Pertussis can lead to serious disease and even death in infants. Older adults are more vulnerable to complications as well. In high-income countries, acellular pertussis vaccines are used for priming vaccination.
Pauline Versteegen +15 more
doaj +1 more source
An infant who suffered seizures many times after pentavalent vaccination: A case report
Although rare, serious adverse effects may be seen after vaccination. Especially, the whole-cell pertussis vaccine has been held responsible for neurological side effects, as the most important problem in vaccination.
Meryem Erat Nergiz +4 more
doaj +1 more source

