Carbohydrate‐Based Drug Discovery: Synthetic Strategies and Clinical Applications
The picture depicts the molecules discussed in the review. On the left side, the general scaffold of sugars is shown. Next to it are four carbohydrate‐based molecules, including remdesivir, islatravir, empagliflozin, and Globo‐H. Remdesivir and islatravir contain a substituted ribose ring attached to a modified nucleobase.
Stephan Scheeff +2 more
wiley +1 more source
The barley–malt–beer chain: A process and food safety approach
Abstract This review addresses the current state of knowledge on the barley–malt–beer chain and its main physical, chemical, and microbiological contaminants, with particular emphasis on spoilage microorganisms and their toxic metabolites. The barley–malt–beer production chain represents a mature and globally relevant agro‐industrial sector that ...
José Gómez‐Espinoza +5 more
wiley +1 more source
m<sup>6</sup>A RNA methylation regulatory gene expression in response to ethanol and acetaldehyde exposure and withdrawal. [PDF]
Koo JS, Zhan Q, Zhang H.
europepmc +1 more source
Techno-economic Analysis and Life Cycle Assessment of Renewable Acetaldehyde from Sugarcane Ethanol
Acetaldehyde has been historically synthesized from ethanol via oxidation. However, since the 1960s, the cost of feedstock and conversion process has gradually driven manufacturers to prefer the liquid-phase oxidation of ethylene.
Jean Felipe Leal Silva +1 more
doaj
Liver Fibrosis: Molecular Pathogenesis and Therapeutic Interventions
We systematically summarized the etiologies, diagnostic approaches, and pathogenic mechanisms of liver fibrosis. Also, the therapeutic interventions for liver fibrosis were systematically classified into two main categories: etiological treatment and mechanism‐based antifibrotic therapies.
Jiaorong Qu +8 more
wiley +1 more source
In-Plant Assessment of Peruvian Pisco Distillates Using Infrared Sensing Technologies. [PDF]
Wu Y +4 more
europepmc +1 more source
Intratumoral Microorganisms in Tumors: Current Understanding and Emerging Therapeutic Strategies
Tumors are no longer viewed as sterile but dynamic ecosystems harboring low‐biomass intratumoral microbiota. These microbes, derived from gut, oral cavity, or circulation, shape tumorigenesis and therapy response via core mechanisms: immunomodulation (regulating T cells, macrophages), metabolic reprogramming (SCFAs, indoles, bile acids), chronic ...
Haoling Zhang +8 more
wiley +1 more source
The Effects of Java Water-Dropwort (<i>Oenanthe javanica</i>) Extract on Alcohol Metabolism and Hangover Symptoms: A Randomized, Double-Blind, Placebo-Controlled Crossover Clinical Trial. [PDF]
Kim YS, Jung CH, Kim SY, Chai H, Kim H.
europepmc +1 more source
Gap Analysis of Metabolic Conversions of Off‐Flavors and Antinutrients in Plant‐Based Substrates
ABSTRACT To drastically reduce the carbon footprint of the food production chain, a major shift towards alternatives to conventional meat and dairy products is required. The use of plant‐based proteins is a promising route, but it also comes with challenges: Plant‐based proteins often contain antinutritional factors and off‐flavors, which can ...
Robin I. Kuijpers +16 more
wiley +1 more source
Carbonyl emissions from heated tobacco products. [PDF]
Zervas E +3 more
europepmc +1 more source

