Results 141 to 150 of about 69,799 (276)

Advancing Biomass Valorization via Electrocatalytic Oxidation: Design Principles, Emerging Challenges, and Future Perspectives

open access: yesSusMat, EarlyView.
This review categorizes substrates for electrocatalytic biomass valorization by carbon chain length into C2–C3 alcohols, C5–C7 cyclic compounds, and Cn biopolymers. It identifies four universal catalyst design principles: optimizing intermediate adsorption, engineering synergistic multi‐type active sites, accelerating active‐site formation, and ...
Ruya Zhang, Shuaihu Jiang, Yijin Kang
wiley   +1 more source

INFLUENCE OF ETHANOL AND ITS FIRST METHABOLITE ACETALDEHYDE ON THE CENTRAL NERVOUS SYSTEM

open access: yesZdravniški Vestnik, 2009
Background Ethanol, a legal drug, is a big social problem in our country. First of all because of addiction development and also due to consequences of the chronic alcoholism. Ethanol effects to almost all organ systems.
Lucija Šarc, Metoda Lipnik Štangelj
doaj  

Comparing clinical laboratory beta‐hydroxybutyrate testing of vitreous humor against toxicological blood analyses in ketoacidosis deaths

open access: yesJournal of Forensic Sciences, EarlyView.
Abstract Beta‐hydroxybutyrate (BHB) is used in investigations to detect ketoacidotic states. Standard chromatographic methods of analysis of blood have traditionally been used to assess BHB levels. More recently, vitreous humor has been an alternative matrix/body fluid in clinical laboratory testing.
Quinn Basso   +3 more
wiley   +1 more source

Nicotine pouches and clinical outcomes related to smoking cessation: A systematic review of randomized trials

open access: yesAddiction, EarlyView.
Abstract Background and aims Tobacco‐free nicotine pouches (NPs) are oral nicotine products promoted by manufacturers and some researchers as tools that may reduce nicotine cravings and support smoking reduction or cessation. However, evidence regarding their actual clinical impact remains limited.
Javad Heshmati   +6 more
wiley   +1 more source

ETHANOL, ACETALDEHYDE AND DOPAMINE NEURONS

open access: yes, 2010
There has been a great deal of activity in recent years in the study of the direct effects of ethanol on the dopamine reward system originating in the ventral tegmental area (VTA).
Muggironi G   +5 more
core  

Rifaximin ameliorates memory impairment and Alzheimer's pathological changes in APP/PS1 mice associated with changes in the gut microbiome–bile acids–serum metabolites networks

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Modifying the brain–gut–microbiota axis has emerged as a promising therapeutic strategy against Alzheimer's disease (AD). Whether rifaximin, a non‐absorbed and non‐systemic antibiotic, can be applied to the treatment of AD remains unexplored.
Di Wu   +7 more
wiley   +1 more source

Common pathways and outliers in glucose catabolism across Trypanosomatidae

open access: yesThe FEBS Journal, EarlyView.
Trypanosomatid parasites, including Trypanosoma sp., Leishmania sp., Phytomonas sp., and Vickermania sp., share a common motif: a metabolism built around the glycosome, a unique peroxisome‐derived organelle housing the first steps of glycolysis. Yet, these organisms have evolved remarkably diverse strategies to catabolize glucose, excreting distinct ...
Fred R. Opperdoes   +5 more
wiley   +1 more source

Metabolic mRNA insufficiency of single cells: Implications for drug targeting and resistance

open access: yesThe FEBS Journal, EarlyView.
Because none of the single‐cell mRNA profiles of growing cell populations encoded any pathway towards cell growth, we used cluster‐averaged transcriptomes to estimate protein‐constrained Vmax's and identify (combinations of) subpopulation‐specific targets to overcome drug resistance. (Graphical Abstract was created in BioRender. Liu, Y. (2026). https://
Yanhua Liu, Hans V. Westerhoff
wiley   +1 more source

Techno-economic Analysis and Life Cycle Assessment of Renewable Acetaldehyde from Sugarcane Ethanol

open access: yesChemical Engineering Transactions
Acetaldehyde has been historically synthesized from ethanol via oxidation. However, since the 1960s, the cost of feedstock and conversion process has gradually driven manufacturers to prefer the liquid-phase oxidation of ethylene.
Jean Felipe Leal Silva   +1 more
doaj  

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