Results 41 to 50 of about 101,023 (246)

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Acetaldehyde exposure alters fibrin polymerization, fibrinolysis, and fibrin network structure in vitro

Research and Practice in Thrombosis and Haemostasis
Background: Fibrin(ogen), the primary structural component of blood clots, plays a critical role in thrombosis and hemostasis. Posttranslational modifications to fibrinogen that occur upon exposure to reactive endogenous metabolites or xenobiotics during
Shakthi Rave, Daniel P. Hu, Rebecca A. Risman, Warishah Khan, Valerie Tutwiler, Lauren G. Poole   +5 more
doaj   +1 more source

Gene specific modifications unravel ethanol and acetaldehyde actions

Frontiers in Behavioral Neuroscience, 2013
Ethanol is metabolized into acetaldehyde mainly by the action of alcohol dehydrogenase in the liver, while mainly by the action of catalase in the brain. Aldehyde dehydrogenase-2 metabolizes acetaldehyde into acetate in both organs.
YEDY eISRAEL, Mario eRivera-Meza, Eduardo eKarahanian, Maria Elena Quintanilla, Lutske eTampier, Paola eMorales, Mario eHerrera-Marschitz   +6 more
doaj   +1 more source

Two highly divergent alcohol dehydrogenases of melon exhibit fruit ripening-specific expression and distinct biochemical characteristics [PDF]

, 2006
Alcohol dehydrogenases (ADH) participate in the biosynthetic pathway of aroma volatiles in fruit by interconverting aldehydes to alcohols and providing substrates for the formation of esters.
A-RS Chen, Alain Latché, B Klein, B Persson, C Aubert, C Tesnière, C Tesnière, C Verriès, D Straeten Van der, Daniel Manríquez, DP Matton, E Moyano, F Fan, F Flores, F Yahyaoui, Farid Regad, Fikri El-Yahyaoui, Francisco B. Flores, G Echeverria, GL Bruxelles De, H Eklund, H Jörnvall, H-P Peng, I El-Sharkawy, I Molina, Islam El-Sharkawy, J Speirs, J Speirs, JC Ingersoll, JD Thompson, Jean-Claude Pech, JJ Salas, JS Peters, K Nakajima, M Guis, MM Bradford, Mondher Bouzayen, N Saitou, P Sarni-Manchado, PK Boss, R Ayub, S Fonseca, S Morrell, S Picton, S Yokoyama, SF Altschul, T Chase Jr, T Longhurst   +47 more
core   +2 more sources

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Acetaldehyde via CGRP receptor and TRPA1 in Schwann cells mediates ethanol-evoked periorbital mechanical allodynia in mice: relevance for migraine

Journal of Biomedical Science, 2023
Background Ingestion of alcoholic beverages is a known trigger of migraine attacks. However, whether and how ethanol exerts its pro-migraine action remains poorly known. Ethanol stimulates the transient receptor potential vanilloid 1 (TRPV1) channel, and
Lorenzo Landini, Daniel Souza Monteiro de Araujo, Martina Chieca, Gaetano De Siena, Elisa Bellantoni, Pierangelo Geppetti, Romina Nassini, Francesco De Logu   +7 more
doaj   +1 more source

Formate Excretion in Urine of Rats Fed Dimethylaminoazobenzene-rich Diets: The Possibility of Formate Formation from D-Lactate [PDF]

, 2008
This experiment was carried out to evaluate the possibility of degradation of d-lactate into formate and acetaldehyde. In order to induce hyperproduction of d-lactate in rats.
Kawase, Michi, Kitamura, Yuki, Ohmori, Shinji   +2 more
core   +1 more source

Combining Three Peripheral Blood Biomarkers to Stratify Rheumatoid Arthritis–Associated Interstitial Lung Disease Risk

Arthritis Care &Research, EarlyView.
Objective The purpose was to evaluate a biomarker score consisting of MUC5B rs35705950 promoter variant, plasma matrix metalloproteinase‐7 (MMP‐7), and serum anti–malondialdehyde‐acetaldehyde (anti‐MAA) antibody for rheumatoid arthritis (RA)–associated interstitial lung disease (ILD) risk stratification.
Kelsey Coziahr, Austin M. Wheeler, Brent A. Luedders, Michael Duryee, Halie Frideres, Katherine D. Wysham, Grant W. Cannon, Gary Kunkel, Dana P. Ascherman, Paul A. Monach, Gail S. Kerr, Andreas M. Reimold, Scott M. Matson, Joshua F. Baker, Geoffrey M. Thiele, Ted R. Mikuls, Bryant R. England   +16 more
wiley   +1 more source

Coupling Electrochemical CO2 Reduction With Ethanol Oxidation for Acetate Production in a Dual‐Electrolyzer System

Angewandte Chemie, EarlyView.
A tandem cell system coupling electrochemical CO2 reduction and electrochemical ethanol oxidation is demonstrated for overall acetate production, providing concepts for a CO2‐negative bioethanol to acetate pathway. ABSTRACT Bioethanol production from biomass is suggested as a strategy for greener fuel production.
Anirudha Shekhawat, Shubhadeep Chandra, Ridha Zerdoumi, Bashir Eid, Muhammad Adib Abdillah Mahbub, Wolfgang Schuhmann   +5 more
wiley   +2 more sources

Determination of carbonyl compounds (acetaldehyde and formaldehyde) in polyethylene terephthalate containers designated for water conservation [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2012
Polyethylene terephthalate (PET) has in the last several years become the main packaging material for many food products, particularly carbonated beverages and bottled water, as well as for products of chemical industry (packaging of various hygiene ...
Redžepović Azra S., Ačanski Marijana M., Vujić Đura N., Lazić Vera L.   +3 more
doaj   +1 more source