Results 91 to 100 of about 258,318 (261)

Effects of fenfluramine and sigma‐1‐dependent pharmacological and genetic modulation in a mouse kindling model

open access: yesEpilepsia, EarlyView.
Abstract Objective Sigma‐1 is a chaperone protein that serves as a key homeostatic regulator, implicated in neuronal excitability and seizure control. Positive allosteric modulators offer a use‐dependent means to enhance Sigma‐1 activity, potentially with favorable tolerability compared to direct agonists.
Eva‐Lotta von Rüden   +5 more
wiley   +1 more source

N-(3,4-Dimethylphenyl)acetamide

open access: yesActa Crystallographica Section E, 2008
The conformation of the N—H bond in the title compound (34DMPA), C10H13NO, is syn to the 3-methyl substituent in the aromatic ring, in contrast to the anti conformation observed with respect to the 3-chloro substituent in N-(3,4-dichlorophenyl ...
B. Thimme Gowda   +2 more
doaj   +1 more source

Polyvinylidene Fluoride: Reaction Engineering and Applications

open access: yesMacromolecular Reaction Engineering, EarlyView.
An updated review on polyvinylidene fluoride (PVDF) is presented in this work. Its properties, important areas of application and different methods of production are described, with particular focus on emulsion polymerization, covering the latest advances in formulations and modeling studies.
Burak Hanamirian   +2 more
wiley   +1 more source

Non‐triazine photosystem II inhibitors provide effective control of metabolic atrazine‐resistant Amaranthus tuberculatus

open access: yesPest Management Science, EarlyView.
Metabolism‐based atrazine‐resistant Amaranthus tuberculatus populations ACR and MCR exhibit little or no cross‐resistance to amicarbazone and metribuzin, suggesting that non‐halogenated Group 5 herbicides can be utilized to re‐establish effective control.
Alexander J Lopez   +5 more
wiley   +1 more source

The continuing significance of chiral agrochemicals

open access: yesPest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Immune escape mechanisms revealed by multifunctional nanoprobes targeting PD‐L1 in hepatic cancer progression

open access: yesVIEW, EarlyView.
The ICGB@Apt nanoprobes are designed to specifically recognize immune checkpoint molecules such as PD‐L1, thereby enabling precise monitoring of the progression from liver cirrhosis to HC. By binding to PD‐L1 on tumor cells, ICGB@Apt visualizes immune escape events and tumor metastasis while simultaneously reflecting the dynamic interaction between ...
Yiteng Meng   +5 more
wiley   +1 more source

2-Bromoacetamide

open access: yesIUCrData
The title compound, C2H4BrNO, crystallizes in the monoclinic space group P21/c with one molecule in the asymmetric unit. The almost planar molecules are organized via N—H...O hydrogen bonds into a ladder-type network, which can be characterized by the ...
Anke Schwarzer, Manuel Stapf
doaj   +1 more source

2,2-Dichloro-N-(3-nitrophenyl)acetamide

open access: yesActa Crystallographica Section E, 2008
The conformation of the N—H bond in the structure of the title compound (3NPDCA), C8H6Cl2N2O3, is anti to the meta-nitro group, similar to that in the structures of 2-chloro-N-(3-nitrophenyl)acetamide (3NPCA) and 2,2,2-trichloro-N-(3-nitrophenyl ...
Hartmut Fuess   +2 more
doaj   +1 more source

5‐HT2A receptor agonism by tert‐leucinamide and valinamide synthetic cannabinoids: In vitro and in vivo evidence

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose New synthetic cannabinoid receptor agonists (SCRAs) are associated with severe adverse effects, including unexpected psychiatric symptoms. These compounds are mainly active through their potent agonism on the cannabinoid receptors CB1 and CB2.
Giorgia Corli   +8 more
wiley   +1 more source

2-Chloro-N-(3-methylphenyl)acetamide

open access: yesActa Crystallographica Section E, 2008
The conformation of the N—H bond in the structure of the title compound, C9H10ClNO, is syn to the meta-methyl group, in contrast to the anti conformation observed with respect to the meta-nitro group in 2-chloro-N-(3-nitrophenyl)acetamide.
B. Thimme Gowda   +4 more
doaj   +1 more source

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