N-(4-Methoxy-2-nitrophenyl)-2-(3-methyl-2-oxo-1,2-dihydroquinoxalin-1-yl)acetamide
IUCrData, 2023 The quinoxaline unit in the title molecule, C18H16N4O5, is slightly puckered [dihedral angle between the rings = 2.07 (12)°] while the whole molecule adopts an L-shaped conformation.
Mohcine Missioui +5 more
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A New Method to Overcome Carboxyamide Formation During AFEX Pretreatment of Lignocellulosic Biomass
Frontiers in Chemistry, 2022 Lignin-carbohydrate complexes (LCCs) in the plant cell wall are responsible for providing resistance against biomass-degrading enzymes produced by microorganisms.
Hui Dong +6 more
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N-(Phenylsulfonyl)acetamide [PDF]
Acta Crystallographica Section E Structure Reports Online, 2010 In the title compound, C(8)H(9)NO(3)S, the N-H bond is in an anti-periplanar conformation with respect to the C=O bond. The crystal packing is stabilized by N-H⋯O hydrogen bonds, generating C(4) chains propagating in [001].
B. Thimme Gowda +3 more
openaire +3 more sources
2-NPPA Mitigates Osteoclastogenesis via Reducing TRAF6-Mediated c-fos Expression
Frontiers in Pharmacology, 2021 Excessive bone resorption leads to bone destruction in pathological bone diseases. Osteoporosis, which occurs when osteoclast-mediated bone resorption exceeds osteoblast-mediated bone synthesis, is regarded a global health challenge.
Zhihao Chen +6 more
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Molecules, 2021 A series of new acetamide derivatives 22–28 of primary and secondary amines and para-toluene sulphinate sodium salt have been synthesized under microwave irradiation and assessed in vitro for their antibacterial activity against one Gram-positive and two
Abdulmajeed S. H. Alsamarrai +1 more
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Rational Design, Synthesis and Biological Evaluation of Pyrimidine-4,6-diamine derivatives as Type-II inhibitors of FLT3 Selective Against c-KIT. [PDF]
, 2018 FMS-like Tyrosine Kinase 3 (FLT3) is a clinically validated target for acute myeloid leukemia (AML). Inhibitors targeting FLT3 have been evaluated in clinical studies and have exhibited potential to treat FLT3-driven AML.
Bharate, Jaideep B +8 more
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3,3′-[(Cyclohexane-1,4-diyl)bis(azanediyl)]bis(cyclohex-2-en-1-one)
IUCrData, 2016 The title compound, C18H26N2O2, crystallizes with two half-molecules in the asymmetric unit, both lying about inversion centres situated at the centers of the cyclohexane rings.
Antar A. Abdelhamida +2 more
doaj +1 more source
Identification of a novel link connecting indole-3-acetamide with abscisic acid biosynthesis and signaling. [PDF]
New PhytolSummary Plants orchestrate their developmental processes and responses to environmental stimuli through a sophisticated network of small signaling molecules, termed phytohormones. Among these, auxins are recognized for their role in promoting plant growth.
Moya-Cuevas J +8 more
europepmc +2 more sources
Unusual products of the aqueous chlorination of atenolol [PDF]
, 2009 The reaction of the drug atenolol with hypochlorite under conditions that simulate wastewater disinfection was investigated. The pharmaceutical reacted in 1 h yielding three products that were separated by chromatographic techniques and characterized by ...
DELLA GRECA, MARINA +4 more
core +1 more source
Crystal structure of 2-cyano-N-(furan-2-ylmethyl)acetamide
Acta Crystallographica Section E: Crystallographic Communications, 2015 In the title compound, C8H8N2O2, the acetamide unit is inclined to the furan ring by 76.7 (1)°. In the crystal, molecules are linked by N—H...O and C—H...O hydrogen bonds, generating C(4) chains along [100].
Shivanna Subhadramma +4 more
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