Results 71 to 80 of about 3,911 (190)

Synthesis and characterization of some novel diaryl urea derivatives bearing quinoxalindione moiety

Research in Pharmaceutical Sciences, 2018
Diaryl urea derivatives have exhibited a broad spectrum of biochemical effects and pharmaceutical applications. Several diaryl urea derivatives such as sorafenib, regorafenib, linifanib, and tivozanib and lenvatinib are in clinical trial or clinical use.
Sedighe Sadeghian-Rizi, Ghadamali Khodarahmi, Amirhossein Sakhteman, Ali Jahanian-Najafabadi, Mahboubeh Rostami, Mahmoud Mirzaei, Farshid Hassanzadeh   +6 more
doaj   +1 more source

2-(Benzhydrylsulfinyl)acetamide

Acta Crystallographica Section E Structure Reports Online, 2004
The title compound, C15H14NO2S, was prepared by the esterification of benzhydryl­thio­acetic acid, followed by amidation and oxidation. There are two independent molecules in the asymmetric unit.
Wen Pei, Li Sun, Yueshui Shao, Dongwei Li   +3 more
openaire   +1 more source

Reliable Estimation of Wavenumbers for Calcite Peaks

Journal of Raman Spectroscopy, EarlyView.
The wavenumbers of the calcite peaks were accurately estimated using a combination of a He–Ne laser and Ne emission lines. The values following the ± symbol represent the expanded uncertainties, corresponding to an approximate 95% confidence interval.
Nobuyasu Itoh
wiley   +1 more source

Synthesis and antiexudative activityof pyrolin derivatives 2 - ((4-amino-5- (furan-2-yl)-1,2,4-triazol-4H-3-il)-sulfanil)-N-acetamides

Фармацевтичний журнал, 2019
The continuous research of new effective drugs is associated with a significant number of diseases, pathological conditions. Conventional treatment with existing drugs could be ineffective, or addictive, and have a large number of side effects. Therefore,
N. M. Chalenko, P. A. Bezugly, A. O. Sirova, I. S. Chekman, A.M. Demchenko   +4 more
doaj   +1 more source

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Crystal structures of two C,N-disubstituted acetamides: 2-(4-chlorophenyl)-N-(2-iodophenyl)acetamide and 2-(4-chlorophenyl)-N-(pyrazin-2-yl)acetamide

Acta Crystallographica Section E: Crystallographic Communications, 2016
In the crystal of 2-(4-chlorophenyl)-N-(2-iodophenyl)acetamide, C14H11ClINO, molecules are linked by a combination of N—H...O and C—H...O hydrogen bonds to form a C(4)C(4)[R21(7)] chain of rings and chains of this type are linked by a combination of C—Cl.
Badiadka Narayana, Hemmige S. Yathirajan, Ravindranath Rathore, Christopher Glidewell   +3 more
doaj   +1 more source

Pure Chitosan Microfluidic Spinning Affords Modular Core‐Sheath Fibers and Hand‐Crafted Scaffolds with Enhanced Fibroblast Compatibility

Small, EarlyView.
Microfluidic Wet Spinning affords highly resilient and biocompatible microfibers of pure chitosan without the use of any crosslinker. We produced microfibers both sheath and core of made of chitosan and another version with a chitosan sheath and chitin nanocrystals in the core.
Ishneet Kaur, Alejandro Forigua, Hatem M. Titi, Yonatan Morocz, David Juncker, Christopher Moraes, Audrey Moores   +6 more
wiley   +1 more source

Engineering Proton Conductive Metal–Organic Glasses Through Secondary Network Formers

Small, EarlyView.
Incorporating secondary network formers enables access to metal–organic glass with tunable structures and properties. This strategy allows systematic control over key metrics, including anhydrous proton conductivities up to 2.6 mS cm−1 at 150°C, a linear increase in glass transition temperature from 11.0°C to 57.4°C, and more than a 200‐fold increase ...
Nattapol Ma, Hideka Ando, Renzhi Ma, Takashi Nakanishi   +3 more
wiley   +1 more source

Understanding how enzymes work: the journey to ensemble–function studies

The FEBS Journal, EarlyView.
For decades, structure–function has dominated biochemistry. Structures are highly valuable, yet more is needed to achieve a quantitative understanding of biomolecular function, because function emerges from an ensemble of states, rather than a static structure. We describe an ensemble–function framework applied to quantitatively dissect serine protease
Daniel Herschlag, Siyuan Du
wiley   +1 more source

Three-Component Reaction of 3-Arylidene-3H-Indolium Salts, Isocyanides, and Alcohols

Frontiers in Chemistry, 2019
A novel isocyanide-based multicomponent synthesis of alkyl aryl(indol-3-yl)acetimidates has been established. Starting from aryl(indol-3-yl)methylium tetrafluoroborates, aromatic isocyanides and alcohols, the imidates were obtained in moderate to very ...
Nikita E. Golantsov, Hung M. Nguyen, Alexandra S. Golubenkova, Alexey V. Varlamov, Erik V. Van der Eycken, Erik V. Van der Eycken, Leonid G. Voskressensky   +6 more
doaj   +1 more source