Results 91 to 100 of about 7,268 (257)
Pest Management Science, EarlyView.Metabolism‐based atrazine‐resistant Amaranthus tuberculatus populations ACR and MCR exhibit little or no cross‐resistance to amicarbazone and metribuzin, suggesting that non‐halogenated Group 5 herbicides can be utilized to re‐establish effective control.
Alexander J Lopez +5 more
wiley +1 more source
Synthesis and biological evaluation of Schiff bases and azetidinones of 1-naphthol
Journal of Pharmacy and Bioallied Sciences, 2012 Introduction: Schiff bases and azetidinones form an important structural class possessing wide spectrum of biological activities that include antibacterial and antifungal activity.
Sushil Kumar, Punit Kumar, Nitin Sati
doaj +1 more source
In silico identification, synthesis and biological evaluation of novel tetrazole inhibitors of MurB [PDF]
, 2018 In the context of antibacterial drug discovery resurgence, novel therapeutic targets and new compounds with alternative mechanisms of action are of paramount importance. We focused on UDP-N- acetylenolpyruvylglucosamine reductase (i.e.
Barreteau, Hélène +7 more
core +3 more sources
The continuing significance of chiral agrochemicals
Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley +1 more source
Synthesis and characterization of some novel diaryl urea derivatives bearing quinoxalindione moiety
Research in Pharmaceutical Sciences, 2018 Diaryl urea derivatives have exhibited a broad spectrum of biochemical effects and pharmaceutical applications. Several diaryl urea derivatives such as sorafenib, regorafenib, linifanib, and tivozanib and lenvatinib are in clinical trial or clinical use.
Sedighe Sadeghian-Rizi +6 more
doaj +1 more source
VIEW, EarlyView.The ICGB@Apt nanoprobes are designed to specifically recognize immune checkpoint molecules such as PD‐L1, thereby enabling precise monitoring of the progression from liver cirrhosis to HC. By binding to PD‐L1 on tumor cells, ICGB@Apt visualizes immune escape events and tumor metastasis while simultaneously reflecting the dynamic interaction between ...
Yiteng Meng +5 more
wiley +1 more source
Фармацевтичний журнал, 2019 The continuous research of new effective drugs is associated with a significant number of diseases, pathological conditions. Conventional treatment with existing drugs could be ineffective, or addictive, and have a large number of side effects. Therefore,
N. M. Chalenko +4 more
doaj +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose New synthetic cannabinoid receptor agonists (SCRAs) are associated with severe adverse effects, including unexpected psychiatric symptoms. These compounds are mainly active through their potent agonism on the cannabinoid receptors CB1 and CB2.
Giorgia Corli +8 more
wiley +1 more source
Understanding how enzymes work: the journey to ensemble–function studies
The FEBS Journal, EarlyView.For decades, structure–function has dominated biochemistry. Structures are highly valuable, yet more is needed to achieve a quantitative understanding of biomolecular function, because function emerges from an ensemble of states, rather than a static structure. We describe an ensemble–function framework applied to quantitatively dissect serine protease
Daniel Herschlag, Siyuan Du
wiley +1 more source
FARM-LEVEL EFFECTS OF ADOPTING HERBICIDE-TOLERANT SOYBEANS IN THE U.S.A. [PDF]
This paper estimates the on-farm impacts of adopting herbicide-tolerant soybean on herbicide use, yields, and farm profits, using an econometric model that corrects for self-selection and simultaneity and is consistent with profit maximization. The model
Fernandez-Cornejo, Jorge +2 more
core +1 more source