Results 91 to 100 of about 5,076 (258)

Potential Local Anaesthetics. Part VII. Synthesis of Diethylamino -Morpholino-Piperidino-N-( Substituted-1, 2-diarylethyl)-Acetamides

open access: yes, 1972
Bapulal H. Vakil Research Laboratory, Shrimati Bhikhuben Chandulal Jalundhwal Science College, Cambay, (Dist Kaira). Received 19 July, 1969 N-1,2-diarylethyl)-chloroacetamides have been condensed with diethylamine, morpholine and piperidine to yield \(
J. J. TRIVEDI, P. B. PATEL
core   +1 more source

Molecular docking binding mode of MOL2008 (1c) and series I paullone-acetamides (1f–h) in the ATP site (S1) of the homology model.

open access: yes, 2023
Molecular docking binding mode of MOL2008 (1c) and series I paullone-acetamides (1f–h) in the ATP site (S1) of the homology model.
Irina Ihnatenko (16415232)   +9 more
core   +1 more source

Investigations Into the Metabolism and Elimination of Flmodafinil and Fladrafinil for Sports Drug Testing Purposes

open access: yesDrug Testing and Analysis, EarlyView.
This article investigates the metabolism and elimination of flmodafinil and fladrafinil, two fluorinated analogs of modafinil and adrafinil listed as S6 stimulants by the World Anti‐Doping Agency. After single‐dose administration to six volunteers, the compounds and their main metabolites were studied in urine and blood.
O. Krug   +6 more
wiley   +1 more source

The Synthesis of N-Substituted Di(2-thienylmethyl)acetamides

open access: yes, 1948
This thesis is a study of the synthesis of N-substituted di(2-thienylmethyl ...
Knox, John A.
core  

ZnO‐Coated Silicon Oxide Nano‐Anode: Synergistic Enhancement of Cycling and Thermal Stability of Lithium‐Ion Batteries

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Lithium‐ion battery anodes that maintain good performance and excellent stability under high temperature conditions. Silicon oxide (SiO) has great potential as a high‐capacity anode for lithium‐ion batteries, but its practical use is limited by excessive volume expansion (>200%) and rapid capacity fade, especially at high temperatures.
Keren Shi   +9 more
wiley   +1 more source

Preparation of N-aryl-4-oxo-4H-1-benzothiopyran-2-acetamides from trilithiated acetoacetanilides and lithiated methyl thiosalicylate

open access: yes, 1999
Acetoacetanilide and substituted acetoacetanilides were trilithiated in excess lithium diisopropylamide, and the polylithiated intermediates were regioselectively condensed with lithiated methyl thiosalicylate, followed by acid cyclization to afford ...
Douglas R Hurst   +7 more
core   +1 more source

Effects of fenfluramine and sigma‐1‐dependent pharmacological and genetic modulation in a mouse kindling model

open access: yesEpilepsia, EarlyView.
Abstract Objective Sigma‐1 is a chaperone protein that serves as a key homeostatic regulator, implicated in neuronal excitability and seizure control. Positive allosteric modulators offer a use‐dependent means to enhance Sigma‐1 activity, potentially with favorable tolerability compared to direct agonists.
Eva‐Lotta von Rüden   +5 more
wiley   +1 more source

Breeding switchgrass for reduced nitrogen demand

open access: yesGrassland Research, EarlyView.
Breeding has improved switchgrass biomass yield, but productivity is still heavily dependent on nitrogen fertilizer application. The genetic diversity needed to improve nitrogen use efficiency of switchgrass remains underused, mainly because of the slow and laborious breeding process, thus leaving the crop's high nitrogen demand as a major barrier to ...
Michael D. Casler, Prabin Bajgain
wiley   +1 more source

Iron-Catalyzed Denitrogenative Annulation Reactions between α‑Azido Acetamides and Cyclic Ketones

open access: yes
We report an FeCl2-catalyzed annulation reaction between α-azido acetamides and cyclic ketones. Two types of α,β-unsaturated γ-lactam products can be obtained, depending on the reaction conditions. When α-azido acetamides were reacted with cyclohexanone,
Wei Yu (43094)   +2 more
core   +1 more source

Microbial keystone taxa and metabolic signatures in centenarians regulate intestinal homeostasis during aging

open access: yesiMeta, EarlyView.
Clostridium scindens and its metabolite indole‐3‐acetic acid (IAA) are identified as a keystone taxon and metabolic signature in centenarians. Clostridium scindens enhances microbial network stability and produces IAA via its own amidase (AMIE) and aldehyde dehydrogenase (ALDH), thus promoting intestinal homeostasis by activating the aryl hydrocarbon ...
Wei‐Chuan Lin   +13 more
wiley   +1 more source

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