Results 101 to 110 of about 4,030 (217)

Methyl on the Bridge: 2‐Methyl Propellane as Precursor for 1,3‐Substituted 2‐Methylated Bicyclo[1.1.1]Pentanes

Chemistry – A European Journal, Volume 32, Issue 28, 25 July 2026.
The synthesis of 2‐methyl propellane and its conversion to various 1,2‐ and 1,2,3‐di‐ and trisubstituted bicyclopentanes is reported. Abstract Bicyclo[1.1.1]pentanes (BCPs) have emerged as isosteric replacements for mono‐ and para‐substituted benzene rings in medicinal and materials applications, involving substitution at the BCP bridgehead (1,3 ...
Sean R. Verschaeve, Mariana Gomes Manso, Tibo Van Eeckhoorn, Mark E. Light, Bruno Linclau   +4 more
wiley   +1 more source

Novel benzothiazole-indole acetamides as potential anticancer agents: synthesis, biological evaluation, and <i>in silico</i> studies. [PDF]

RSC Adv
Motamedi Shakib N, Negahdaripour M, Sayahi MH, Dastyafteh N, Dehghani Z, Emami M, Safapoor S, Ghasemi Y, Ghafouri SN, Ghahramani A, Mohajeri-Tehrani MR, Larijani B, Mahdavi M, Ranjbar S.   +13 more
europepmc   +1 more source

Cross‐Carboxylation of Methanol and Other Alcohols With CO2 Into Asymmetric Alkyl Methyl Carbonates Over a CeO2 Catalyst

Chemistry – A European Journal, Volume 32, Issue 27, 17 July 2026.
One‐pot synthesis of asymmetric organic carbonates from CO2, methanol, and other alcohols was demonstrated in the presence of CeO2 catalyst and 2‐cyanopyridine dehydrant. This reaction proceeded through two reaction pathways—direct route via cross‐carboxylation and indirect route via production of DMC and subsequent transesterification.
Yuan Li, Zechen Li, Mizuho Yabushita, Yoshinao Nakagawa, Keiichi Tomishige   +4 more
wiley   +1 more source

Identification of α-Azacyclic Acetamide-Based Inhibitors of <i>P. falciparum</i> Na⁺ Pump (<i>Pf</i>ATP4) with Fast-Killing Asexual Blood-Stage Antimalarial Activity by Phenotypic Screening. [PDF]

ACS Infect Dis
Casas A, Imlay LS, Thathy V, Fairhurst KJ, Lehane AM, Lawong AK, Deni I, Striepen J, Lee S, Kumar A, Xing C, Niederstrasser H, Posner BA, Laleu B, Charman SA, Fidock DA, Ready JM, Phillips MA.   +17 more
europepmc   +1 more source

Design and Synthesis of Novel Imidazo[4,5‐c]pyridine Derivatives, Evaluation of Their Activity Against Hepatitis C Virus and In Silico Prediction of Their Binding Mode to NS4B Protein

ChemMedChem, Volume 21, Issue 13, 14 July 2026.
A series of 18 novel imidazo[4,5‐c]pyridines was synthesized, and their anti‐HCV activity was evaluated. Compound 30b was identified as the most promising one, with EC50 = 6.61 µM. Molecular docking studies indicated the NS4B protein of the HCV as a potential target of these derivatives.
Eftychia Karampella, George Mpekoulis, Maria Georgiou, Iris Kolida, Katerina I. Kalliampakou, Eirini P. Kollia, Eleni V. Mikropoulou, Maria Halabalaki, Christos T. Chasapis, Niki Vassilaki, Nikolaos Lougiakis   +10 more
wiley   +1 more source

Toward Sustainable Carbonylation Reactions Enabled by CO Surrogates in Green Solvents

ChemSusChem, Volume 19, Issue 13, 14 July 2026.
Carbonylation reactions offer a sustainable route to valuable carbonyl compounds. This review highlights methodologies that exploit carbonylative coupling to drastically enhance process sustainability, avoiding the direct use of CO through CO surrogates and promoting syntheses in green solvents potentially derived from renewable and sustainable sources.
Francesco Messa, Serena Perrone, Antonio Salomone   +2 more
wiley   +1 more source

Synthesis and bioactivity of novel 2-(1,2 benzisothiazol-3-yloxy)-N-(1-aryl-3-cyanopyrazol-5-yl) acetamides

ARKIVOC, 2020
Peng Yu, Xi Li, Xiao Zhang, Yanhua Xu
doaj   +1 more source

Synthesis of 2-(Quinoxalin-2-yl)acetamides and Their Preliminary Cytotoxic and Antibacterial Activity. [PDF]

Chem Biodivers
Tovar-Roman CE, Hernández-Vázquez E, Rivera-Chávez JA.   +2 more
europepmc   +1 more source

Design, Synthesis, and Computational Studies of Novel <i>N-</i>(Substituted phenyl)-3-(5-((naphthalen-2-yloxy)methyl)-4-phenyl‑4<i>H</i>‑1,2,4-triazol-3-ylthio)acetamides as Potent Acetylcholinesterase Inhibitors. [PDF]

ACS Omega
Ayub M, Siddiqui SZ, Rehman AU, Abbasi MA, Parveen R, Ali Shah SA, Mushtaq A, Iqbal J, Khalid H, Imran S, Abbas G.   +10 more
europepmc   +1 more source

Fixed into acetamides [PDF]

Nature Catalysis, 2019
openaire   +1 more source