Results 121 to 130 of about 7,268 (257)

Assessment of amination reactions via nucleophilic aromatic substitution using conventional and eco-friendly energies

Green Chemistry Letters and Reviews, 2018
The efficiency of conventional heating energy source compared with Infrared (IR), Ultrasound (US), Microwave and the simultaneous combination US–IR eco-friendly approaches for preparation of new N-(5-R1 -amino-2-nitrophenyl)acetamides and 5-R1-amino-2 ...
Ricardo A. Luna-Mora, Ángeles Torres-Reyes, Oscar A. González-Cruz, Fernando Ortega-Jiménez, Hulme Ríos-Guerra, Jessica V. González-Carrillo, Francisco Barrera-Téllez, Javier Perez-Flores, José G. Penieres-Carrillo   +8 more
doaj   +1 more source

Inhibitors Targeting SARS‐CoV‐2 Papain‐Like Protease: Screening, Design, Synthesis, and Biological Evaluation

ChemMedChem, Volume 21, Issue 9, 14 May 2026.
In our study, we obtained both non‐covalent and covalent PLpro inhibitors. Additionally, the stable protein‐ligand interactions of the active compound were examined using advanced computational docking and molecular dynamics simulations. The non‐covalent inhibitor 2t showed antiviral activity with an EC50 of 2.89 µM, indicating its potential as a ...
Elena‐Oriana Iuga, Nilu Gone, Mariana Ortiz de Godoy, Gabriel Correa Verissimo, Giovanna de Jesus Agostinetto, Liam Urich, Nadine Krüger, Thales Kronenberger, Rafael Victorio Carvalho Guido, Anthony J. O’Donoghue, Stefan A. Laufer, Thanigaimalai Pillaiyar   +11 more
wiley   +1 more source

1,4‐Pentanediol as an Alternative Biomass‐Derived Medium for the Phosphine‐Free Heck Coupling Reactions

ChemSusChem, Volume 19, Issue 9, 14 May 2026.
In this research, a phosphine‐free Heck coupling reaction was performed using biomass‐derived 1,4‐pentanediol and a polar protic solvent. It was demonstrated that a wide scope of products could be isolated by a simple filtration, eliminating the high‐solvent‐consuming column chromatography and reducing the E‐factor by more than 90% compared to ...
Csaba Árvai, László T. Mika
wiley   +1 more source

Forging Sustainable Carbon–Nitrogen Bonds from CO2 and NOx: Mechanistic Insights and Catalyst Design for Electrochemical CN Coupling

ChemSusChem, Volume 19, Issue 9, 14 May 2026.
Electrochemical CN coupling enables the direct conversion of CO2/CO and NOx into value‐added organonitrogen compounds under mild and sustainable conditions. Catalyst architecture governs the coactivation of carbon and nitrogen intermediates and their interfacial coupling, dictating reaction pathways, selectivity, and efficiency.
Soo Jin Jeon, Chengkai Xia, Jun Young Kim   +2 more
wiley   +1 more source

2-(4-Hydroxyphenyl)acetamide

IUCrData
In the title molecule, C 8 H 9 NO 2 , which is an isomer of acetaminophen [ N -(4-hydroxyphenyl)acetamide], the acetamide group plane subtends a dihedral angle of 89.95 (5)°
Kester, Allison, King, Taylor, Bond, Marcus R.   +2 more
openaire   +2 more sources

Estimation of Bilirubin Using Acetamide

Clinical Chemistry, 1964
Abstract A study of the effect of acetamide as an accelerator of the reaction between free bilirubin and diazotized sulfanilic acid (DSA) has led to its use in a method for serum bilirubin which is simple, sensitive, linear over a wide range, and which requires neither excessive dilution nor protein precipitation.
openaire   +2 more sources

Drugs for preventing red blood cell dehydration in people with sickle cell disease. [PDF]

, 2018
BACKGROUND: Sickle cell disease is an inherited disorder of hemoglobin, resulting in abnormal red blood cells. These are rigid and may block blood vessels leading to acute painful crises and other complications.
Ballas, Samir K., Nagalla, Srikanth
core   +1 more source

O2‐Mediated Cu‐Catalyzed Dehydrogenative Sulfilimination of Tyrosines and Bioactive Phenols

Advanced Synthesis &Catalysis, Volume 368, Issue 9, 5 May 2026.
We report herein the mild O2‐mediated Cu‐catalyzed dehydrogenative sulfilimination of diverse bioactive phenols with simple sulfenamides. The bioconjugation of unmodified native peptides, in particular at their tyrosine units with the dehydrogenative phenochalcogenazination reaction, has attracted much attention lately due to potential click type ...
Fang Xiao, Frederic W. Patureau
wiley   +1 more source

SYNTHESIS OF NEW N-PHENYL-N-(1-PHENYLHEX-5-EN-1-YL)ACETAMIDES AND THEIR 1H-NMR CONFORMATIONAL STUDY

Revista Colombiana de Química, 2014
The synthesis and characterization of different N-phenyl-N-(1-phenylhex-5-en-1-yl)acetamides is presented. Two conformational isomers were observed for one of the compounds in their1H/13C-NMR spectra.
Mauricio Acelas, Elizabeth Gil, Markus Doerr, Martha Daza, Juan Manuel Urbina   +4 more
doaj  

One‐Step Glycoengineering of NK Cells With High‐Affinity Siglec Ligands for Cancer Immunotherapy

Advanced Science, Volume 13, Issue 26, 8 May 2026.
This study develops an engineered NmCSS enzyme with improved activity for bulky group modified sialic acids, enabling efficient synthesis of structurally diverse sialoside analogs in a single step. Glycan microarray screening identified Siglec high‐affinity ligands, which were incorporated onto natural killer (NK) cells via a one‐pot enzymatic system ...
Shuai Hu, Ben Huang, Lingyan Wang, Qiang Guo, Cuiping Jiang, Ruicheng Qi, Shuyao Wang, Lin‐Tai Da, Wenjie Peng   +8 more
wiley   +1 more source