Results 141 to 150 of about 136,607 (334)

Urine discoloration after acetaminophen overdose. [PDF]

open access: bronze, 1986
P M Clark, J. David Clark, T. Wheatley
openalex   +1 more source

Quantitative Systems Toxicology Modeling of Acetaminophen Pharmacokinetics and Hepatic Biomarkers After Overdoses of Extended‐Release and Immediate‐Release Formulations in Adults With Chronic Alcohol Use or Low Glutathione

open access: yesCPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Acetaminophen (APAP), an over‐the‐counter analgesic and antipyretic, can cause hepatotoxicity when ingested in large overdoses. APAP has multiple formulations including immediate‐release (IR) and extended‐release (ER) preparations. A recently published consensus statement on the management of APAP poisoning indicated that management of APAP‐ER
Kyunghee Yang   +8 more
wiley   +1 more source

Specific Items of Enhanced Recovery After Surgery for Liver Surgery in Cirrhotic Patients: A Systematic Review

open access: yesWorld Journal of Surgery, EarlyView.
Enhanced Recovery After Surgery (ERAS) pathways have been shown to be safe in patients undergoing hepatectomy. Due to cirrhosis‐induced complications, specific or additional perioperative items might need to be implemented. This study systematically reviewed the literature to assess specific items to be included in future ERAS protocol for the ...
Gaëtan‐Romain Joliat   +5 more
wiley   +1 more source

Oral MIB‐626 (β Nicotinamide Mononucleotide) Safely Raises Blood Nicotinamide Adenine Dinucleotide Levels in Hospitalized Patients With COVID‐19 and Acute Kidney Injury: A Randomized Controlled Trial

open access: yesFASEB BioAdvances, EarlyView.
This randomized, placebo‐controlled trial assessed the effects of NAD augmentation by administration of oral β Nicotinamide Mononucleotide (β NMN) 1.0 g twice daily or placebo for 14 days in adult patients hospitalized with COVID‐19 and acute kidney injury on blood NAD, plasma levels of NAD metabolites, biomarkers of acute kidney injury, inflammation ...
Karol M. Pencina   +15 more
wiley   +1 more source

Comparative Analysis Of Zebrafish And Planarian Model Systems For Developmental Neurotoxicity Screens Using An 87-Compound Library [PDF]

open access: yes, 2019
There is a clear need to establish and validate new methodologies to more quickly and efficiently screen chemicals for potential toxic effects, particularly on development. The emergence of alternative animal systems for rapid toxicology screens presents
Collins, Eva-Maria S.   +4 more
core   +1 more source

The Prevalence and Severity of Pain in Patients With Systemic Sclerosis

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT We investigated pain prevalence and severity in systemic sclerosis (SSc) and patient–physician perceptions. This was an internet‐based survey that compared perceptions of pain type, location, severity, associated factors between patients with SSc and physicians, and pain treatment prescription patterns in Japan in March 2023.
Sei‐ichiro Motegi   +6 more
wiley   +1 more source

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