Results 151 to 160 of about 127,361 (186)
Some of the next articles are maybe not open access.
Anesthesiology Clinics, 2010
Acetaminophen has unique analgesic and antipyretic properties. It is globally recommended as a first-line agent for the treatment of fever and pain due to its few contraindications. Acetaminophen lacks the significant gastrointestinal and cardiovascular side effects associated with nonsteroidal anti-inflammatory drugs and narcotics.
Jonathan S, Jahr, Vivian K, Lee
openaire +2 more sources
Acetaminophen has unique analgesic and antipyretic properties. It is globally recommended as a first-line agent for the treatment of fever and pain due to its few contraindications. Acetaminophen lacks the significant gastrointestinal and cardiovascular side effects associated with nonsteroidal anti-inflammatory drugs and narcotics.
Jonathan S, Jahr, Vivian K, Lee
openaire +2 more sources
Clinics in Liver Disease, 2003
Unlike the bulk of medications, described in this fascicle, that cause liver injury in humans, acetaminophen is a non-prescription drug that can be purchased in drug stores and supermarkets without a physician's involvement. Death or severe injury is far more likely to occur with its use than with all the other medications considered in this study ...
Matthew Q, Bromer, Martin, Black
openaire +2 more sources
Unlike the bulk of medications, described in this fascicle, that cause liver injury in humans, acetaminophen is a non-prescription drug that can be purchased in drug stores and supermarkets without a physician's involvement. Death or severe injury is far more likely to occur with its use than with all the other medications considered in this study ...
Matthew Q, Bromer, Martin, Black
openaire +2 more sources
Clinics in Laboratory Medicine, 2006
Acetaminophen (acetyl-para-amino-phenol or APAP), an antipyretic and analgesic, is a common component in hundreds of over-the-counter and prescription medications. The wide usage of this drug results in many potentially toxic exposures. It is therefore critical for the clinician to be comfortable with the diagnosis and treatment of APAP toxicity ...
Adam K, Rowden +3 more
openaire +2 more sources
Acetaminophen (acetyl-para-amino-phenol or APAP), an antipyretic and analgesic, is a common component in hundreds of over-the-counter and prescription medications. The wide usage of this drug results in many potentially toxic exposures. It is therefore critical for the clinician to be comfortable with the diagnosis and treatment of APAP toxicity ...
Adam K, Rowden +3 more
openaire +2 more sources
Orthopaedic Nursing, 1997
Acetaminophen is the most widely used and recommended nonprescription analgesic and antipyretic medication in the United States (Rose, 1994). Because acetaminophen is widely advertised and readily available over the counter, consumers as well as health care professionals perceive this medication to be nontoxic.
J A, Roach, B, Stacey
openaire +2 more sources
Acetaminophen is the most widely used and recommended nonprescription analgesic and antipyretic medication in the United States (Rose, 1994). Because acetaminophen is widely advertised and readily available over the counter, consumers as well as health care professionals perceive this medication to be nontoxic.
J A, Roach, B, Stacey
openaire +2 more sources
Gastroenterology, 1980
This review of acetaminophen hepatotoxicity begins with a history of the drug and consideration of the scope of its current use. The molecular basis for hepatotoxicity is discussed and this serves as a background for delineation of its clinical manifestations and treatment.
openaire +3 more sources
This review of acetaminophen hepatotoxicity begins with a history of the drug and consideration of the scope of its current use. The molecular basis for hepatotoxicity is discussed and this serves as a background for delineation of its clinical manifestations and treatment.
openaire +3 more sources
Emergency Medicine Clinics of North America, 1984
N-acetylcysteine (NAC) is the treatment of choice for acetaminophen overdose. With this therapy, morbidity from overdose can be held to a minimum. Mortality is rare in any case and virtually nonexistent in treated patients. Unless a high index of suspicion is maintained, the diagnosis may be missed until it is too late for effective antidotal treatment.
C H, Linden, B H, Rumack
openaire +2 more sources
N-acetylcysteine (NAC) is the treatment of choice for acetaminophen overdose. With this therapy, morbidity from overdose can be held to a minimum. Mortality is rare in any case and virtually nonexistent in treated patients. Unless a high index of suspicion is maintained, the diagnosis may be missed until it is too late for effective antidotal treatment.
C H, Linden, B H, Rumack
openaire +2 more sources
The American Journal of Medicine, 1983
Acetaminophen is a remarkably safe agent when used in therapeutic doses. Most reported overdoses of acetaminophen are the result of suicide attempts. The clinical course of patients with toxic blood levels follows four distinct stages. Symptoms of nausea, vomiting, diaphoresis, and anorexia usually begin within seven to 14 hours after ingestion.
openaire +2 more sources
Acetaminophen is a remarkably safe agent when used in therapeutic doses. Most reported overdoses of acetaminophen are the result of suicide attempts. The clinical course of patients with toxic blood levels follows four distinct stages. Symptoms of nausea, vomiting, diaphoresis, and anorexia usually begin within seven to 14 hours after ingestion.
openaire +2 more sources
Digestive Diseases and Sciences, 2000
To determine the influence of psychosocial factors in accidental and deliberate acetaminophen overdose, we reviewed the charts of 207 overdose patients, and 48 met our criteria for acetaminophen toxicity. Two patients died. A psychiatric history was present in 75%, and 25% had a previous or subsequent suicide attempt.
T A, Broughan, R D, Soloway
openaire +2 more sources
To determine the influence of psychosocial factors in accidental and deliberate acetaminophen overdose, we reviewed the charts of 207 overdose patients, and 48 met our criteria for acetaminophen toxicity. Two patients died. A psychiatric history was present in 75%, and 25% had a previous or subsequent suicide attempt.
T A, Broughan, R D, Soloway
openaire +2 more sources
Pediatrics, 1973
Acetaminophen* is being increasingly used as a mild analgesic/antipyretic both as a replacement for phenacetin and as a substitute for aspirin. In Britain the current consumption of acetaminophen has been estimated to be about 50% of that of aspirin, which in turn has been calculated to be the equivalent of 6,000 million tablets per year.1
openaire +2 more sources
Acetaminophen* is being increasingly used as a mild analgesic/antipyretic both as a replacement for phenacetin and as a substitute for aspirin. In Britain the current consumption of acetaminophen has been estimated to be about 50% of that of aspirin, which in turn has been calculated to be the equivalent of 6,000 million tablets per year.1
openaire +2 more sources
Clinics in Liver Disease, 2007
Acetaminophen is a commonly used antipyretic and analgesic agent. It is safe when taken at therapeutic doses; however, overdose can lead to serious and even fatal hepatotoxicity. The initial metabolic and biochemical events leading to toxicity have been well described, but the precise mechanism of cell injury and death is unknown. Prompt recognition of
openaire +2 more sources
Acetaminophen is a commonly used antipyretic and analgesic agent. It is safe when taken at therapeutic doses; however, overdose can lead to serious and even fatal hepatotoxicity. The initial metabolic and biochemical events leading to toxicity have been well described, but the precise mechanism of cell injury and death is unknown. Prompt recognition of
openaire +2 more sources