Results 71 to 80 of about 113,832 (239)

Use of Negative Control Exposure Analysis to Evaluate Confounding: An Example of Acetaminophen Exposure and Attention-Deficit/Hyperactivity Disorder in Nurses’ Health Study II

American Journal of Epidemiology, 2019
Frequent maternal use of acetaminophen in pregnancy has been linked to attention-deficit/hyperactivity disorder (ADHD) in children, but concerns regarding uncontrolled confounding remain.
Z. Liew, Marianthi-Anna Kioumourtzoglou, A. Roberts, Éilis J. O’Reilly, A. Ascherio, M. Weisskopf   +5 more
semanticscholar   +1 more source

Leptin receptor gene polymorphisms and sex modify the association between acetaminophen use and asthma among young adults: results from two observational studies

Respiratory Research, 2018
Background Epidemiologic studies have demonstrated associations between acetaminophen use and asthma. This investigation sought to determine whether sex modifies the acetaminophen-asthma association and whether leptin (LEP) and leptin receptor (LEPR ...
Ali H. Ziyab, Nandini Mukherjee, Ramesh J. Kurukulaaratchy, Hongmei Zhang, Susan Ewart, Hasan Arshad, Wilfried Karmaus   +6 more
doaj   +1 more source

Mitochondrial–Lysosomal Axis in Acetaminophen Hepatotoxicity

Frontiers in Pharmacology, 2018
Acetaminophen (APAP) toxicity is the most common cause of acute liver failure and a major indication for liver transplantion in the United States and Europe. Although significant progress has been made in understanding the molecular mechanisms underlying
A. Moles, S. Torres, A. Baulies, C. Garcia-Ruiz, J. Fernández-Checa   +4 more
semanticscholar   +1 more source

Association between Chronic Acetaminophen Exposure and Allergic Rhinitis in a Rat Model

Allergy & Rhinology, 2015
Background Several population studies demonstrated an increased risk of allergic rhinitis in patients exposed to acetaminophen. However, no histologic studies have been conducted to assess the relationship between acetaminophen exposure and allergic ...
Nadieska Caballero M.D., Kevin C. Welch M.D., Patrick S. Carpenter M.D., Swati Mehrotra M.D., Tom F. O'Connell M.D., Eileen M. Foecking Ph.D.   +5 more
doaj   +1 more source

Histopathological effects with marwar teak (tecomella undulata) bark extract and N-acetylcysteine on acetaminophen induced hepatotoxicity in albino rats.

, 2022
Mehr Fatima, Muhammad Kamran, Shabih Zehra, Nighat Jamil, Ijaz Hussain Zaidi   +4 more
openalex   +2 more sources

Biochemical and Histological Effects of Thiamine Pyrophosphate against Acetaminophen‐Induced Hepatotoxicity [PDF]

, 2015
Hilal Bektaş Uysal, Bekir Dağlı, M. Yılmaz, Fadime Kahyaoğlu, Alparslan Gökçimen, İmran Kurt Ömürlü, Buket Demirci   +6 more
openalex   +1 more source

The role of oxidative stress, inflammation and acetaminophen exposure from birth to early childhood in the induction of autism

Journal of International Medical Research, 2017
The wide range of factors associated with the induction of autism is invariably linked with either inflammation or oxidative stress, and sometimes both.
William Parker, C. Hornik, S. Bilbo, Z. E. Holzknecht, L. Gentry, Rasika Rao, Shu-sen Lin, M. Herbert, C. Nevison   +8 more
semanticscholar   +1 more source

The mitochondrial negative regulator MCJ is a therapeutic target for acetaminophen-induced liver injury

Nature Communications, 2017
Acetaminophen (APAP) is the active component of many medications used to treat pain and fever worldwide. Its overuse provokes liver injury and it is the second most common cause of liver failure.
Lucía Barbier-Torres, P. Iruzubieta, David Fernández‐Ramos, T. C. Delgado, D. Taibo, Virginia Guitiérrez-de-Juan, M. Varela-Rey, M. Azkargorta, N. Navasa, Pablo Fernández-Tussy, Imanol Zubiete‐Franco, Jorge Simón, F. Lopitz‐Otsoa, Sofía Lachiondo‐Ortega, J. Crespo, S. Masson, M. McCain, E. Villa, H. Reeves, F. Elortza, M. Lucena, M. Hernández-Alvarez, A. Zorzano, R. Andrade, Shelly C. Lu, J. Mato, J. Anguita, M. Rincón, M. Martínez‐Chantar   +28 more
semanticscholar   +1 more source

Cardiac Consequences of Massive Acetaminophen Overdose

, 2023
Jessica M. Mann, Marie Pierre-Louis, Peter J. Kragel, Amy H. Kragel, William C. Roberts   +4 more
openalex   +1 more source

Old and New Analgesic Acetaminophen: Pharmacological Mechanisms Compared with Non-Steroidal Anti-Inflammatory Drugs

Future Pharmacology
Although it is more than a century since it was first marketed, acetaminophen remains one of the most popular analgesic agents. In addition, acetaminophen has recently been applied to multimodal analgesia in combination with non-steroidal anti ...
Hironori Tsuchiya, Maki Mizogami
doaj   +1 more source