Results 31 to 40 of about 34,477 (255)
Journal of Enzyme Inhibition and Medicinal Chemistry, 2022 Neisseria gonorrhoeae is a high-priority pathogen of concern due to the growing prevalence of resistance development against approved antibiotics. Herein, we report the anti-gonococcal activity of ethoxzolamide, the FDA-approved human carbonic anhydrase ...
Nader S. Abutaleb +8 more
doaj +1 more source
Frontiers in Neurology, 2023 BackgroundCerebral hemodynamics in moyamoya disease (MMD) is complex and needs further elucidation. The primary aim of the study was to determine the association of the cerebrovascular reserve (CVR) with cerebral blood flow (CBF) disturbances, oxygen ...
Teodor Svedung Wettervik +4 more
doaj +1 more source
Adverse events associated with intraocular injection of anti-VEGF(bevacizumab) in retinal vein ccclusion: a case report [PDF]
, 2015 Introduction: Antiangiogenic agents are often administered for treatment of Branch Retinal Vein Occlusion (BRVO). Among them, Bevacizumab has noticeable antiangiogenic and antiedemigenic properties and possesses great capacity to penetrate the retinal ...
ARTICO, Marco +7 more
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Keratoprostheses for corneal blindness: a review of contemporary devices [PDF]
, 2015 According to the World Health Organization, globally 4.9 million are blind due to corneal pathology. Corneal transplantation is successful and curative of the blindness for a majority of these cases. However, it is less successful in a number of diseases
Avadhanam, Venkata +2 more
core +1 more source
Question Answering with Subgraph Embeddings [PDF]
, 2014 This paper presents a system which learns to answer questions on a broad range of topics from a knowledge base using few hand-crafted features. Our model learns low-dimensional embeddings of words and knowledge base constituents; these representations ...
Bordes, Antoine +2 more
core +2 more sources
Ataxia in children: early recognition and clinical evaluation [PDF]
, 2017 Background: Ataxia is a sign of different disorders involving any level of the nervous system and consisting of impaired coordination of movement and balance.
Falsaperla, Raffaele +6 more
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Molecular Basis and Differentiation-Associated Alterations of Anion Secretion in Human Duodenal Enteroid Monolayers [PDF]
, 2018 Background & Aims: Human enteroids present a novel tool to study human intestinal ion transport physiology and pathophysiology. The present study describes the contributions of Cl- and HCO3 - secretion to total cyclic adenosine monophosphate (cAMP ...
Avula, L.R. (Leela Rani) +6 more
core +5 more sources
PulmonologyBackground The carbonic anhydrase inhibitor acetazolamide stimulates ventilation through metabolic acidosis mediated by renal bicarbonate excretion. In animal models, acetazolamide attenuates acute hypoxia-induced pulmonary hypertension (PH), but its ...
M. Lichtblau +11 more
doaj +1 more source
Efficacy of Acetazolamide in Refractory Epilepsy Management: A Quasi-Experimental Study
Pakistan Armed Forces Medical Journal, 2023 Objective: To assess the efficacy of Acetazolamide in refractory epilepsy management. Study Design: Quasi-experimental study. Place and Duration of Study: Outpatient Neurology Department, Allied Hospital, Faisalabad Pakistan, from Sep 2020 to Feb ...
Muhammad Ahmed Zamir +4 more
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Recovery from acidosis is a robust trigger for loss of force in murine hypokalemic periodic paralysis. [PDF]
, 2019 Periodic paralysis is an ion channelopathy of skeletal muscle in which recurrent episodes of weakness or paralysis are caused by sustained depolarization of the resting potential and thus reduction of fiber excitability.
Cannon, Stephen C +4 more
core +1 more source