Results 31 to 40 of about 18,535 (225)
Acute mountain sickness (AMS) is an ilness, that occurs in non-acclimatized individuals after rapid ascent to high altitude, typically above 2,500 metres (8,000 ft).
Karol Mazur+4 more
doaj +1 more source
Acetazolamide: Old drug, new evidence?
Acetazolamide is an old drug used as an antiepileptic agent, amongst other indications. The drug is seldom used, primarily due to perceived poor efficacy and adverse events. Acetazolamide acts as a noncompetitive inhibitor of carbonic anhydrase, of which
Arif Ali Shukralla+2 more
doaj +1 more source
Novel Sulfonylhydrazones With Sulfonate Ester Framework: Promising Dual Inhibitors of AChE and hCAs
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder that affects millions of individuals worldwide. Treatment strategies for AD vary depending on cognitive and behavioral symptoms, with cholinergic replacement therapy using acetylcholinesterase (AChE) inhibitors being one of the primary approaches.
Cansu Öztürk+3 more
wiley +1 more source
ABSTRACT In this study, novel thiosemicarbazone derivative molecules (5a–j) were synthesized. The characterization of the synthesized molecules was carried out using 1H–, 13C–NMR, FT–IR, and Q–TOF spectroscopic techniques. Then, the inhibitory effect of these compounds was examined for human carbonic anhydrase I and II (hCA I, and II) and ...
Hayreddin Gezegen+4 more
wiley +1 more source
Acetazolamide (molecular mass (MM), 222) belongs to the class of sulfonamides (R-SO2-NH2) and is one of the strongest pharmacological inhibitors of carbonic anhydrase activity. Acetazolamide is excreted unchanged in the urine.
Olga Begou+3 more
doaj
Background Studies in human medicine have concluded that acetazolamide reduces pain associated with carbon dioxide insufflation during laparoscopic surgery.
Inês T. Tavares+6 more
doaj +1 more source
Surgical interventions, like barbed reposition pharyngoplasty (BRP), are a valuable alternative for patients with obstructive sleep apnea (OSA) who are unable to tolerate continuous positive airway pressure (CPAP).
Simon Hellemans+9 more
doaj +1 more source
Graphical presentation of the study design, main results and conclusion. Abbreviations: Y/O = year old; HFpEF = heart failure with preserved ejection fraction; Kg = kilograms; NYHA = New York Heart Association; ACE = angiotensin‐converting enzyme; ARB = angiotensin receptor blockers; ARNI = angiotensin receptor‐neprilysin inhibitor; SGLT2i = sodium ...
Amit Gruber+14 more
wiley +1 more source
Acetazolamide-induced bilateral ciliochoroidal effusion syndrome in plateau iris configuration
Purpose: Our purpose is to describe a 60-year-old male, who has plateau iris configuration and developed bilateral ciliochoroidal effusion syndrome after ingestion of acetazolamide.
Xiaofei Man+3 more
doaj +1 more source
The ABDOPOCUS‐HF trial is a randomized, single‐blind, low‐intervention clinical trial (n = 168) investigating the utility of intra‐abdominal pressure (IAP) and point of care ultrasound to guide decongestive therapies during the first 72 hours after admission for acute heart failure.
C. Josa‐Laorden+20 more
wiley +1 more source