Results 71 to 80 of about 29,225 (214)
Mechanism of Cd-Induced Inhibition of Na-Glucose Cotransporter in Rabbit Proximal Tubule Cells: Roles of Luminal pH and Membrane-Bound Carbonic Anhydrase [PDF]
Background/Aims: We have previously reported that a complex of cadmium-metallothionein (Cd-MT) directly affects the apical Na-glucose cotransporter on the luminal side in proximal tubules, suggesting that Cd-MT is more toxic than CdCl2 in causing ...
Fujimura Akio +4 more
core +1 more source
Abstract Objective This study was conducted to provide a clinically oriented, mechanism‐based framework for interpreting neuroimaging across disorders of cerebrospinal fluid (CSF) pressure, with particular emphasis on patients who fall between classic diagnostic categories of spontaneous intracranial hypotension (SIH) and idiopathic intracranial ...
Andrew L. Callen, Kyle Jenkins
wiley +1 more source
Phosphorylation and protonation of neighboring MiRP2 sites: function and pathophysiology of MiRP2-Kv3.4 potassium channels in periodic paralysis. [PDF]
MinK-related peptide 2 (MiRP2) and Kv3.4 subunits assemble in skeletal muscle to create subthreshold, voltage-gated potassium channels. MiRP2 acts on Kv3.4 to shift the voltage dependence of activation, speed recovery from inactivation, suppress ...
Abbott, Geoffrey W +2 more
core +1 more source
Treatment of acute cryptococcal meningitis in HIV infected adults, with an emphasis on resource-limited settings [PDF]
BACKGROUND: Despite the advent and increasingly wide availability of antiretroviral therapy, cryptococcal meningitis (CM) remains a significant cause of mortality and morbidity amongst individuals with HIV infection in resource-limited settings.
Dedicoat, Martin +3 more
core +1 more source
Huntington's Disease‐like Syndrome as a Rare Presentation of CACNA1A‐Related Disorder
Movement Disorders Clinical Practice, EarlyView.
Petros Boumis +14 more
wiley +1 more source
Phenotypic characteristics of paroxysmal dyskinesia in 25 cats
Objectives Paroxysmal dyskinesia has, to date, been reported only systematically in Sphynx cats. This study aims to describe paroxysmal dyskinesia in additional breeds. Materials and Methods The medical records of cats from multiple hospitals presenting with episodes consistent with paroxysmal dyskinesia between 2020 and 2025 were retrospectively ...
T. Liatis +5 more
wiley +1 more source
Patients' Perceptions and Treatment Effectiveness [PDF]
An extensive literature relating patients’ expectations to treatment outcomes has not addressed the determinants of these expectations. We argue that treatment history is part of a reference point that influences patients’ expectations of how effective ...
Dan Firesner +3 more
core
Andersen-Tawil syndrome (ATS) is a rare condition consisting of ventricular arrhythmias, periodic paralysis, and dysmorphic features. In 2001, mutations in KCNJ2, which encodes the α subunit of the potassium channel Kir2.1, were identified in patients ...
Smith, Andrew H +2 more
core +1 more source
Role of extracellular carbonic anhydrase in the polar diatom Fragilariopsis cylindrus
Summary Diatoms are major primary producers in productive polar oceans, where cold temperatures and high CO2 solubility raise questions as to whether they rely on the CO2‐concentrating mechanism (CCM) to saturate photosynthesis. Knowledge of CCM function will help better predict the sensitivity of diatom primary production to warming and acidifying ...
Meng Li, Jodi N. Young
wiley +1 more source
We investigated the involvement of calcium-activated potassium channel (BK) in skeletal muscle phenotype determination and response to acetazolamide, a BK opener.
Domenico Tricarico +2 more
doaj +1 more source

