Results 91 to 100 of about 20,539 (219)

Phenotype-dependent functional and pharmacological properties of BK channels in skeletal muscle: Effects of microgravity

open access: yesNeurobiology of Disease, 2005
We investigated the involvement of calcium-activated potassium channel (BK) in skeletal muscle phenotype determination and response to acetazolamide, a BK opener.
Domenico Tricarico   +2 more
doaj   +1 more source

Acetazolamide potentiates the afferent drive to prefrontal cortex in vivo [PDF]

open access: yes, 2017
The knowledge on real-time neurophysiological effects of acetazolamide is still far behind the wide clinical use of this drug. Acetazolamide – a carbonic anhydrase inhibitor – has been shown to affect the neuromuscular transmission, implying a pH ...
Leite, Joao   +5 more
core   +1 more source

The role of acid‐base balance in cerebrovascular and ventilatory responses to CO2 during 10 h normobaric hypoxia

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend During 10 h exposures to normobaric hypoxia exposure there was a selective leftward shift in ventilatory response to hyperoxic hypercapnic rebreathing, but not the cerebrovascular response. The key findings are that the resetting of the central chemoreflex to lower PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_2}}}$ during early hypoxic ...
Holly Barclay   +3 more
wiley   +1 more source

Safety and Tolerability of Acetazolamide [PDF]

open access: yes, 2015
Idiopathic intracranial hypertension (IIH) is a disease of unknown etiology that occurs primarily in young obese women with an estimated incidence of 0.9/100,00 in the general population1.
Martin ten Hove
core  

Augmenting erythropoiesis using recombinant human erythropoietin at sea level blunts the high altitude induced increase in erythropoiesis

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Pharmacologically augmenting erythropoiesis with rEPO at sea level blunts the high altitude induced erythropoiesis. Abstract Erythropoiesis increases with high altitude (HA) acclimatization. Recombinant human erythropoietin (rEPO) induces erythropoiesis.
Roy M. Salgado   +15 more
wiley   +1 more source

Acetazolamide as a singlet molecular oxygen quencher [PDF]

open access: yes, 2013
According to literature the acetazolamide, which is commonly used as a diuretic, shows phototoxic properties. To contribute to the understanding of the role of this chemical as a generator of the very common toxic substance, the singlet molecular oxygen,
Tobon, Eduard   +2 more
core   +1 more source

High‐altitude headache: Insights into pathophysiology and potential treatment implications

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude headache occurs during prolonged exposure to low oxygen, such as during ascent to high altitude. Several risk factors increase its likelihood, with the degree of hypoxia, often driven by rapid ascent to greater altitudes, being the most prominent factor.
Marika Falla   +3 more
wiley   +1 more source

Acetazolamide responsive episodic ataxia treated with methazolamide: a case report [PDF]

open access: yes, 2015
Acetazolamide-responsive ataxia is a rare episodic ataxia (EA) disorder characterized by paroxysmal cerebellar ataxia. Many of the symptoms with EA can be treated with the carbonic anhydrase inhibitor acetazolamide. EA is a family of channelopathies each
Lakhan, Shaheen E
core   +1 more source

Idiopathic Intracranial Hypertension Is Characterized by a Distinct Proteomic Profile

open access: yesAnnals of Neurology, Volume 100, Issue 2, Page 255-267, August 2026.
Objectives The pathophysiology of idiopathic intracranial hypertension (IIH) is poorly understood and disease‐specific biomarkers are lacking. We aimed to shed light on IIH pathophysiology and identify disease‐specific biomarkers. Methods This prospective cross‐sectional cohort study included patients with new‐onset IIH and age‐, body mass index‐, and ...
Santosh D. Bhosale   +17 more
wiley   +1 more source

Effect of acetazolamide and methazolamide on diaphragm and dorsiflexor fatigue: a randomized controlled trial [PDF]

open access: yes, 2018
Acetazolamide, a carbonic anhydrase (CA) inhibitor used clinically and to prevent acute mountain sickness, worsens skeletal muscle fatigue in animals and humans.
Lucas J. Teppema   +8 more
core   +1 more source

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