Carbonic anhydrase inhibitor attenuates ischemia-reperfusion induced acute lung injury. [PDF]
PLoS ONE, 2017 Ischemia-reperfusion (IR)-induced acute lung injury (ALI) is implicated in several clinical conditions including lung transplantation, cardiopulmonary bypass surgery, re-expansion of collapsed lung from pneumothorax or pleural effusion and etc.
Chou-Chin Lan +4 more
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Drug-drug interaction signals between carbonic anhydrase inhibitors and vitamin D preparations in urinary tract stones: disproportionality analysis evaluation from Japanese spontaneous reports of adverse events [PDF]
Journal of Pharmaceutical Health Care and SciencesBackground Carbonic anhydrase inhibitors used as antiepileptic drugs promote calcium phosphate stones. Patients with epilepsy often receive vitamin D concurrently, which may increase urinary calcium and stone formation. We analyzed drug-drug interactions
Teruhisa Kinoshita +4 more
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(Z)-N-(3-([1,1'-biphenyl]-2-yl)-4-heptyl-4-hydroxythiazolidin-2-ylidene)-4-bromobenzamide as carbonic anhydrase inhibitor: exploration of its in vitro and in silico studies [PDF]
BMC ChemistryHuman Carbonic Anhydrase inhibitors (CAIs) have been clinically used to treat a variety of disorders, such as cancer, obesity, haemolytic anaemia, glaucoma, retinopathy, and epilepsy.
Aftab Ahmed +10 more
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Crystal structure of Brinzolamide: a carbonic anhydrase inhibitor [PDF]
Acta Crystallographica Section E: Crystallographic Communications, 2016 In crystal structure of the title compound, C12H21N3O5S3 [systematic name: (R)-4-ethylamino-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide], there exist three kinds of hydrogen-bonding interactions.
Huirong Zheng, Benyong Lou
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Capsaicin: A Potent Inhibitor of Carbonic Anhydrase Isoenzymes
Molecules, 2014 Carbonic anhydrase (CA, EC 4.2.1.1) is a zinc containing metalloenzyme that catalyzes the rapid and reversible conversion of carbon dioxide (CO2) and water (H2O) into a proton (H+) and bicarbonate (HCO3–) ion.
Betul Arabaci +2 more
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Aspirin: A Suicide Inhibitor of Carbonic Anhydrase II
Biomolecules, 2020 Carbonic anhydrase II (CAII) is a metalloenzyme that catalyzes the reversible hydration/dehydration of CO2/HCO3−. In addition, CAII is attributed to other catalytic reactions, including esterase activity. Aspirin (acetyl-salicylic acid), an everyday over-
Jacob Andring +2 more
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Perfusion-Based Bioreactor Culture and Isothermal Microcalorimetry for Preclinical Drug Testing with the Carbonic Anhydrase Inhibitor SLC-0111 in Patient-Derived Neuroblastoma [PDF]
International Journal of Molecular Sciences, 2022 Ivan Martin +2 more
exaly +2 more sources
Microbiology Spectrum, 2023 The ADC (AmpC) β-lactamase is universally present in the Acinetobacter baumannii chromosome, suggesting it may have a yet-to-be-identified cellular function. Using peptidoglycan composition analysis, we show that overexpressing the ADC-7 β-lactamase in A.
Jennifer M. Colquhoun +6 more
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Multivalent Carbonic Anhydrases Inhibitors [PDF]
International Journal of Molecular Sciences, 2019 Biomolecular recognition using a multivalent strategy has been successfully applied, this last decade on several biological targets, especially carbohydrate-processing enzymes, proteases, and phosphorylases. This strategy is based on the fact that multivalent interactions of several inhibitory binding units grafted on a presentation platform may ...
Fabrizio Carta +3 more
openaire +3 more sources
Frontiers in Plant Science, 2021 We studied bicarbonate-induced stimulation of photophosphorylation in thylakoids isolated from leaves of Arabidopsis thaliana plants. This stimulation was not observed in thylakoids of wild-type in the presence of mafenide, a soluble carbonic anhydrase ...
Tatiana P. Fedorchuk +6 more
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