Results 21 to 30 of about 47,659 (268)

Mechanisms of carbon dioxide detection in the earthworm Dendrobaena veneta

Frontiers in Ecology and Evolution, 2023
IntroductionCarbon dioxide (CO2) is a critical biological signal that is noxious to many animals at high concentrations. The earthworm Dendrobaena veneta lives in subterranean burrows containing high levels of CO2 and respires through its skin.
Emily Jordan Smith, Emily Jordan Smith, Jennifer L. Ryan, Sofia A. Lopresti, Dastan B. S. Haghnazari, Karleigh A. S. Anderson, Sarah J. Lipson, Erik C. Johnson, Wayne L. Silver, Cecil J. Saunders, Cecil J. Saunders   +10 more
doaj   +1 more source

Electrolyte and Water Balance of the Early Avian Embryo: Effects of Egg Turning [PDF]

, 2002
Formation of sub-embryonic fluid (SEF) is a key aspect of the physiology of the early avian embryo.Here we review the process of SEF formation and the factors which influence its composition and the rate of SEF production and depletion in the Japanese ...
Baggott, Glenn K., Deeming, D.C., Latter, G.V.   +2 more
core   +1 more source

Acetazolamide in the treatment of acute mania - A case report [PDF]

, 1998
Several antiepileptic drugs are also being used in affective disorders. There are some hints that also the carbonic anhydrase inhibitor acetazolamide might be useful in the treatment of bipolar affective disorder.
Brandt, C., Grunze, Heinz, Normann, C., Walden, Jörg   +3 more
core   +1 more source

Nanoarchitectonics and Molecular Docking of 4-(Dimethylamino)Pyridin-1-Ium 2-3 Methyl-4-Oxo-Pyri-Do[1,2-a]Pyrimidine-3-Carboxylate

Crystals, 2023
A retro-Claisen reaction of 1-(4-oxo-4H-pyrido [1,2-a]pyrimidin-3-yl)butane-1,3-dione, 3, in the presence of potassium hydroxide and 4-dimethylamino-pyridine has been carried out, leading to 4-(dimethylamino)pyridin-1-ium 2-methyl-4-oxo-pyrido [1,2-a ...
Sanae Lahmidi, El Hassane Anouar, Walid Ettahiri, Mohamed El Hafi, Fatima Lazrak, Mohammed M. Alanazi, Ashwag S. Alanazi, Mohamed Hefnawy, El Mokhtar Essassi, Joel T. Mague   +9 more
doaj   +1 more source

The sheep conceptus modulates proteome profiles in caruncular endometrium during early pregnancy [PDF]

, 2016
This project was funded by NHS Grampian R&D project number RG05/019Peer ...
Al-Gubory, Kaïs, Arianmanesh, Mitra, Fowler, Paul A   +2 more
core   +2 more sources

Inhibitory effects of sulfenimides on human and bovine carbonic anhydrase enzymes

Journal of Enzyme Inhibition and Medicinal Chemistry, 2023
A series of sulfenimide derivatives (1a-i) were investigated as inhibitors of human (hCA-I, hCA-II) and bovine (bCA) carbonic anhydrase enzymes. The compounds were synthesised by the reaction of substituted thiophenols with phthalimide by means of an ...
Hasan Yakan, Gürkan Bilir, Şükriye Çakmak, Ömer Taş, Nalan Türköz Karakullukçu, Ercan Soydan, Halil Kütük, Coşkun Güçlü, Murat Şentürk, Tayfun Arslan, Seyhan Öztürk, Ercüment Aksakal, Deniz Ekinci   +12 more
doaj   +1 more source

The effects of cardiac drugs on human erythrocyte carbonic anhydrase I and II isozymes

Journal of Enzyme Inhibition and Medicinal Chemistry, 2020
Cardiovascular diseases are the leading cause of mortality worldwide. In recent years, the relationship between carbonic anhydrase inhibitors and atherosclerosis has attracted attention.
Onur Argan, Kübra Çıkrıkçı, Aybike Baltacı, Nahit Gencer   +3 more
doaj   +1 more source

Quinazolinones as Competitive Inhibitors of Carbonic Anhydrase-II (Human and Bovine): Synthesis, in-vitro, in-silico, Selectivity, and Kinetics Studies

Frontiers in Chemistry, 2020
Carbonic anhydrase-II (CA-II) is associated with glaucoma, malignant brain tumors, and renal, gastric, and pancreatic carcinomas and is mainly involved in the regulation of the bicarbonate concentration in the eyes. CA-II inhibitors can be used to reduce
Ajmal Khan, Majid Khan, Majid Khan, Sobia Ahsan Halim, Zulfiqar Ali Khan, Zahid Shafiq, Ahmed Al-Harrasi   +6 more
doaj   +1 more source

Carbonic anhydrase inhibitor acetazolamide shifts synaptic vesicle recycling to a fast mode at the mouse neuromuscular junction [PDF]

, 2017
Acetazolamide (AZ), a molecule frequently used to treat different neurological syndromes, is an inhibitor of the carbonic anhydrase (CA), an enzyme that regulates pH inside and outside cells.
Bertone Cueto, Nicolás Iván, Cano, Raquel, Groisman, Ayelén Ivana, Mazzone, Graciela Luján, Tabares, Lucía, Uchitel, Osvaldo Daniel   +5 more
core   +1 more source

Synthesis, molecular modelling and QSAR study of new N-phenylacetamide-2-oxoindole benzensulfonamide conjugates as carbonic anhydrase inhibitors with antiproliferative activity

Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
In continuation of our previous studies to optimise potent carbonic anhydrase inhibitors, two new series of isatin N-phenylacetamide based sulphonamides were synthesised and screened for their human (h) carbonic anhydrase (EC 4.2.1.1) inhibitory ...
Mona F. Said, Riham F. George, Andrea Petreni, Claudiu T. Supuran, Nada M. Mohamed   +4 more
doaj   +1 more source