Results 81 to 90 of about 22,014 (216)

Acetazolamide in Hydrocephalus Management

open access: yes, 1995
The efficacy of treatment with acetazolamide (100 mg/kg/day) without frusemide in arresting post-hemorrhagic ventricular dilatation was evaluated in 3 infants at the Hammersmith Hospital, London ...
J Gordon Millichap
core   +1 more source

The role of acid‐base balance in cerebrovascular and ventilatory responses to CO2 during 10 h normobaric hypoxia

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend During 10 h exposures to normobaric hypoxia exposure there was a selective leftward shift in ventilatory response to hyperoxic hypercapnic rebreathing, but not the cerebrovascular response. The key findings are that the resetting of the central chemoreflex to lower PCO2${P_{{\mathrm{C}}{{\mathrm{O}}_2}}}$ during early hypoxic ...
Holly Barclay   +3 more
wiley   +1 more source

Phenotype-dependent functional and pharmacological properties of BK channels in skeletal muscle: Effects of microgravity

open access: yesNeurobiology of Disease, 2005
We investigated the involvement of calcium-activated potassium channel (BK) in skeletal muscle phenotype determination and response to acetazolamide, a BK opener.
Domenico Tricarico   +2 more
doaj   +1 more source

Acetazolamide potentiates the afferent drive to prefrontal cortex in vivo [PDF]

open access: yes, 2017
The knowledge on real-time neurophysiological effects of acetazolamide is still far behind the wide clinical use of this drug. Acetazolamide – a carbonic anhydrase inhibitor – has been shown to affect the neuromuscular transmission, implying a pH ...
Leite, Joao   +5 more
core   +1 more source

Augmenting erythropoiesis using recombinant human erythropoietin at sea level blunts the high altitude induced increase in erythropoiesis

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Pharmacologically augmenting erythropoiesis with rEPO at sea level blunts the high altitude induced erythropoiesis. Abstract Erythropoiesis increases with high altitude (HA) acclimatization. Recombinant human erythropoietin (rEPO) induces erythropoiesis.
Roy M. Salgado   +15 more
wiley   +1 more source

High‐altitude headache: Insights into pathophysiology and potential treatment implications

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude headache occurs during prolonged exposure to low oxygen, such as during ascent to high altitude. Several risk factors increase its likelihood, with the degree of hypoxia, often driven by rapid ascent to greater altitudes, being the most prominent factor.
Marika Falla   +3 more
wiley   +1 more source

Rosemary metabolite carnosic acid opens Kv1.1 via its voltage sensor and corrects Kv1.1‐linked episodic ataxia in mice

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 20, Page 6179-6198, October 2026.
Background and Purpose Episodic ataxia type 1 (EA1) is an autosomal dominant neurological disorder caused primarily by loss‐of‐function mutations in the voltage‐gated potassium channel Kv1.1 (KCNA1). Small molecules that restore Kv1.1 activity hold promise as targeted therapies for EA1, yet current pharmacological strategies remain limited ...
Rían W. Manville   +6 more
wiley   +1 more source

Vibrational study of acetazolamide polymorphism

open access: yes, 2009
In this paper, an acetazolamide vibrational study has been conducted to identify its two known polymorphic forms (A and B). Other techniques, such as Hot-stage and X-ray powder diffraction, have been also reported.
M. C. Gamberini   +9 more
core   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 9, Page 1817-1830, September 2026.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

Acetazolamide for Idiopathic Intracranial Hypertension: An Up-to-Date Review in 2025 [PDF]

open access: yes
Jaffer Naqvi,1 Michael Wall,1 Sophia M Chung,1 Matthew Thurtell,1 Edward Linton,1,2 Adriana Rodriguez-Barrath,1,3 Randy Kardon1,2 1Department of Ophthalmology and Visual Science, Neuro-Ophthalmology Division, University of Iowa Carver College of Medicine,
Naqvi J   +6 more
core  

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