Results 61 to 70 of about 6,792,844 (335)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Removal of gaseous acetic acid using ionic liquid [EMIM][BF4]

Green Energy & Environment, 2019
This work proposed to use the ionic liquid [EMIM][BF4] as absorbent for the absorption of gaseous acetic acid. The feasibility of this technology was investigated from molecular level to industrial scale. The acetic acid absorption experiment was carried
Mingli Mu, Jun Cheng, Chengna Dai, Ning Liu, Zhigang Lei, Yanzhou Ding, Jianjiang Lu   +6 more
doaj   +1 more source

Acetic acid positively modulates proline metabolism for mitigating PEG-mediated drought stress in Maize and Arabidopsis

Frontiers in Plant Science, 2023
IntroductionOsmotic imbalance is one of the major consequences of drought stress, negatively affecting plant growth and productivity. Acetic acid has modulatory roles in osmotic balance in plants; however, the mechanistic insights into acetic acid ...
Sakil Mahmud, Mohammad Kamruzzaman, Mohammad Kamruzzaman, Sabarna Bhattacharyya, Khadiga Alharbi, Diaa Abd El Moneim, Mohammad Golam Mostofa, Mohammad Golam Mostofa   +7 more
doaj   +1 more source

Antioxidant Capacity Of Frangipani (Plumeria Alba) Powder Extract [PDF]

, 2011
This research aimed to identify the antioxidant capacity, vitamin C (ascorbic acid), and total phenolic compounds of frangipani flower powder. The powder was extracted using ethanol, methanol, acetic acid, and water (aquadest).
Bagiada, N. A. (Nyoman), Mantik Astawa, I Nyoman, Wirawan, I. G. (I), Wrasiati, L. P. (Luh)   +3 more
core  

Stir Bar Sorptive Extraction of Volatile Compounds in Vinegar: Validation Study and Comparison With Solid Phase Microextraction [PDF]

, 2007
Stir bar sorptive extraction was evaluated for analysing volatiles in vinegar. The procedure developed shows detection and quantitation limits, and linear ranges adequate for analysing this type of compounds. The accuracy obtained was close to 100%, with
Alves, Baltussen, Bicchi, Blanch, Buettner, Carmelo García Barroso, Demyttenaere, Durán, Edwards, Enrique Durán Guerrero, García, García-Falcón, Hayasaka, Isogai, León, Luan, Luan, Marín, Natera, Noble, Palacios, Quirós, Ramón Natera Marín, Rapp, Remedios Castro Mejías, Zalacain   +25 more
core   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Influence and Mechanism of Polar Solvents on the Retention Time of Short-Chain Fatty Acids in Gas Chromatography

Separations, 2022
Short-chain fatty acids (SCFAs), produced by microbes when dietary fiber ferments in the colon, are one of the most studied microbial products despite their volatility and complex matrices, which make analysis challenging. In the current study, we sought
Mu Ren, Narantsogt Natsagdorj, Na Shun
doaj   +1 more source

Laboratory and field evaluation of acetic acid-based lures for male Asian citrus psyllid, Diaphorina citri. [PDF]

, 2019
The Asian citrus psyllid (ACP) is a vector of a pathogen associated with greening and thus a major problem in citriculture worldwide. Lures are much needed for improving ACP trapping systems for monitoring populations and surveillance.
Bento, José Mauricio S, Calvo, Carolina, de Carvalho, Rômulo Igor, de Freitas, Renato, Delfino, Jennifer Y, Esperança, Victoria, Gonzalez, Francisco, Leal, Walter S, Lehan, Benjamin J, Luvizotto, Rejane AG, Magnani, Rodrigo F, Miranda, Marcelo P, Mulinari, Tatiana Aparecida, Oehlschlager, Cameron A, Volpe, Haroldo XL, Zanardi, Odimar Z   +15 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source