Results 181 to 190 of about 2,889,328 (295)

Butyrate ameliorates acute‐on‐chronic liver failure by regulating macrophage polarization

open access: yesiMetaOmics, EarlyView.
Multi‐omics profiling identifies progressive microbiota‐metabolism‐immunity axis dysfunction in acute‐on‐chronic liver failure (ACLF), characterized by gut dysbiosis, reduced butyrate production, intestinal barrier disruption, microbial translocation, and pro‐inflammatory macrophage polarization, thereby exacerbating hepatic inflammation and fibrosis ...
Jing Xiao   +10 more
wiley   +1 more source

Skin‐like ultra‐sensitive gas flow sensing based on ionically conductive organogels

open access: yesInfoMat, EarlyView.
An elaborately designed gas flow sensor based on organogels was employed to precisely monitor trace gas flow disturbances. Leveraging a reversible ion‐mediated cooperative effect, the skin‐like gas flow sensor exhibited excellent sensing performance toward gas flow, featuring low operation voltage and high sensitivity.
Jiaying Yun   +11 more
wiley   +1 more source

Molecular Characterization of Microorganisms, Pectinolytic Potential and Volatile Compound Formation During Spontaneous Fermentation of Criollo Cacao (<i>Theobroma cacao</i> L.). [PDF]

open access: yesFoods
Alvites-Chuquizuta LL   +10 more
europepmc   +1 more source

Hematological and Genotoxic Effects of Subchronic Oral Exposure to a Mancozeb‐Based Fungicide in Female Mice

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT The extensive use of pesticides in modern agriculture has raised increasing concerns regarding the potential biological effects of repeated exposure to pesticide residues and commercial formulations. Mancozeb is a widely used ethylene‐bis‐dithiocarbamate fungicide; however, information on its hematological and genotoxic effects following ...
Matheus Henrique Barcelos Figueiredo   +10 more
wiley   +1 more source

Effects of Glyphosate and Glyphosate‐Based Herbicides on the Mammalian Gut Microbiome: A Critical Review

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Glyphosate has long been considered to pose negligible direct risk to mammals on the grounds that its molecular target, 5‐enolpyruvylshikimate‐3‐phosphate synthase (EPSPS), of the shikimate pathway, is absent from animal cells. This rationale is inaccurate as a complete toxicological argument, because the shikimate pathway is present in some ...
Robin Mesnage
wiley   +1 more source

Improving protein secretion with autophagy‐inhibiting or proteasome‐activating small molecules

open access: yesJournal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Therapeutic proteins are produced frequently by mammalian cells in large‐scale bioreactors. As a result, producer cells are exposed to a chemically (nutrients, gas exchange, target protein overexpression) and physically (shear due to mixing) stressful environment, which can lead to endoplasmic reticulum (ER) stress and loss of ...
R Chauncey Splichal   +2 more
wiley   +1 more source

Effects of Partial Pulp Removal on Microbial Dynamics and Metabolite Profiles During On-Farm Cocoa Fermentation. [PDF]

open access: yesFoods
Chagas-Junior GCA   +9 more
europepmc   +1 more source

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