Results 221 to 230 of about 86,728 (368)

Model‐Guided Systematic Metabolic Engineering for Enhanced Spinosad Biosynthesis in Saccharopolyspora spinosa NHF132

Advanced Science, Volume 12, Issue 47, December 18, 2025.
A genome‐scale model guided the systematic metabolic engineering of Saccharopolyspora spinosa, enabling a 5.5‐fold boost in the green bioinsecticide spinosad to 1.8 g L−1 and establishing an actinomycete framework for complex natural products overproduction.
Shuliu Wang, Yuxin Liu, Qian Zhang, Yue Jiang, Xiaoqian Zeng, Chengyu Zhang, Jiagao Cheng, Weishan Wang, Lixin Zhang, Gao‐Yi Tan   +9 more
wiley   +1 more source

Optimization of Malonyl Coenzyme A Biosensors in a Reconstituted Cell-Free System for Detecting Acetyl-CoA Carboxylase Activity. [PDF]

ACS Synth Biol
Ito S, Nishikawa S, Terasaka N, Fujishima K.   +3 more
europepmc   +1 more source

Overexpression of Acetyl CoA Carboxylase 1 and 3 (ACCase1 and ACCase3), and CYP81A21 were related to cyhalofop resistance in a barnyardgrass accession from Arkansas. [PDF]

Plant Signal Behav, 2023
González-Torralva F, Norsworthy JK.
europepmc   +1 more source

Structure–activity relationships for a novel series of thiazolyl phenyl ether derivatives exhibiting potent and selective acetyl-CoA carboxylase 2 inhibitory activity

, 2006
Richard F. Clark, Tianyuan Zhang, Zhili Xin, Gang Liu, Ying Wang, Terkel Hansen, Xiaojun Wang, Rongqi Wang, Xiaolin Zhang, Ernst U. Frevert, Heidi S. Camp, Bruce A. Beutel, Hing L. Sham, Yu Gu   +13 more
openalex   +1 more source

WZ66, a novel acetyl-CoA carboxylase inhibitor, alleviates nonalcoholic steatohepatitis (NASH) in mice [PDF]

, 2019
Yingsheng Gao, Minyi Qian, Qiangqiang Wei, Xubin Duan, Shi-Lei Wang, Hai Hu, Jun Liu, Chuyue Pan, Shuo-quan Zhang, Lian‐Wen Qi, Jinpei Zhou, Huibin Zhang, Lirui Wang   +12 more
openalex   +1 more source

Genome‐Wide Protein Interaction Analysis in Parasitic Gyrodactylus Flatworms–Fish Hosts System and Drug Target Identification

Advanced Science, Volume 12, Issue 45, December 4, 2025.
Genomic data offer a powerful tool for studying the molecular interactions between parasites and their hosts, but they remain scarce for parasitic monogenean flatworms. This study presents the first high‐quality phased genome assembly for monogeneans (Gyrodactylus kobayashii), and uses it to predict key interacting proteins between monogenean parasite ‐
Dong Zhang, Jie‐Mei Zhao, Chuan‐Yu Xiang, Yi‐Wen Ma, Hong‐Peng Lei, Yu‐Ying Shi, Shun Zhou, Xiaofei Zeng, Jinsong Chen, Fei Liu, Benhe Zeng, Rui Song, Ye Hu, Feng Zhang, Xiang Liu, Wen‐Xiang Li, Gui‐Tang Wang, Ivan Jakovlić   +17 more
wiley   +1 more source

The sensor histidine kinase (SLN1) and acetyl-CoA carboxylase (ACC1) coordinately regulate the response of Neurospora crassa to the springtail Sinella curviseta (Collembola: Entomobryidae) attack. [PDF]

Appl Environ Microbiol, 2023
Sun M, Lu T, Chen P, Wang X, Yang H, Zhou R, Zheng W, Zhao Y.   +7 more
europepmc   +1 more source

Treatment of Obesity and Related Disorders with Acetyl-CoA Carboxylase Inhibitors

, 2012
Ahmed F. Abdel‐Magid
openalex   +1 more source

Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence.

Cell Metabolism, 2017
Marcos Rios Garcia, B. Steinbauer, Kshitij Srivastava, M. Singhal, F. Mattijssen, A. Maida, Sven Christian, H. Hess-Stumpp, H. Augustin, K. Müller-Decker, P. Nawroth, S. Herzig, M. Berriel Diaz   +12 more
semanticscholar   +1 more source

Succinic Acid Production by Engineered Mannheimia succiniciproducens and Its Use in Chemoenzymatic Poly(Butylene Succinate) Synthesis

Biotechnology and Bioengineering, Volume 122, Issue 12, Page 3393-3405, December 2025.
Succinic acid is produced by the fermentation of metabolically engineered Mannheimia succiniciproducens, purified, and used to synthesize poly(butylene succinate) using a two‐step process that involves the esterification of succinic acid and ethanol, followed by enzymatic transesterification of diethyl succinate and 1,4‐butanediol.
Ji Yeon Kim, Jong An Lee, Gi Bae Kim, Youngjoon Lee, Sang Yup Lee   +4 more
wiley   +1 more source