Results 191 to 200 of about 28,974 (220)
Utilization, metabolic regulation and applications of hydrophobic substrates in <i>Yarrowia lipolytica</i>. [PDF]
Synth Syst BiotechnolZhu F, Zhang L, Wen J.
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Overexpression of acetyl-CoA synthetase (ACS) enhances the biosynthesis of neutral lipids and starch in the green microalga Chlamydomonas reinhardtii [PDF]
Algal Research, 2018 Genetic engineering can be the solution to achieve the economically feasible production of microalgal based biofuels and other bulk materials. A good number of microalgal species can grow mixotrophically using acetate as carbon source.
Richard P Haslam +2 more
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Inflammatory bowel disease (IBD), encompassing Ulcerative Colitis (UC) and Crohn’s Disease (CD), is characterized by chronic gastrointestinal inflammation driven by genetic, environmental, immune, and microbial factors. Acetyl-CoA Synthetase Short Chain Family Member 2 (ACSS2), an enzyme converting acetate to acetyl-CoA, is known to regulate gene ...
Mezher, Nawal
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Modern Pathology, 2017
Acetyl-CoA synthetase-2 is an emerging key enzyme for cancer metabolism, which supplies acetyl-CoA for tumor cells by capturing acetate as a carbon source under stressed conditions. However, implications of acetyl-CoA synthetase-2 in colorectal carcinoma may differ from other malignancies, because normal colonocytes use short-chain fatty acids as an ...
Jeong Mo, Bae +6 more
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Acetyl-CoA synthetase-2 is an emerging key enzyme for cancer metabolism, which supplies acetyl-CoA for tumor cells by capturing acetate as a carbon source under stressed conditions. However, implications of acetyl-CoA synthetase-2 in colorectal carcinoma may differ from other malignancies, because normal colonocytes use short-chain fatty acids as an ...
Jeong Mo, Bae +6 more
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Urologic Oncology: Seminars and Original Investigations, 2018
Acetyl-CoA synthetase 2 (ACSS2) is highly expressed in various cancers, whereas ACSS2 expression and function in renal cell carcinoma (RCC) are unknown.We investigated ACSS2 expression in 198 human RCC tissues using immunohistochemistry, and analyzed its clinicopathological correlation and prognostic relevance.
Shaojin, Zhang +4 more
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Acetyl-CoA synthetase 2 (ACSS2) is highly expressed in various cancers, whereas ACSS2 expression and function in renal cell carcinoma (RCC) are unknown.We investigated ACSS2 expression in 198 human RCC tissues using immunohistochemistry, and analyzed its clinicopathological correlation and prognostic relevance.
Shaojin, Zhang +4 more
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Clinical Cancer Research, 2020
Abstract Introduction and Objective: Cisplatin is an important chemotherapeutic agent against metastatic bladder cancer, but resistance often limits its usage. With the recent recognition of lipid metabolic alterations in bladder cancers, we studied the metabolic implications of cisplatin resistance using cisplatin-sensitive (T24S) and ...
He Wen +6 more
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Abstract Introduction and Objective: Cisplatin is an important chemotherapeutic agent against metastatic bladder cancer, but resistance often limits its usage. With the recent recognition of lipid metabolic alterations in bladder cancers, we studied the metabolic implications of cisplatin resistance using cisplatin-sensitive (T24S) and ...
He Wen +6 more
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The FASEB Journal, 2017
Post‐translational modifications of proteins control many complex biological processes, including genome expression, chromatin dynamics, metabolism, and cell division. Histone protein acetylation and methylation have been extensively linked to the regulation of chromatin remodeling and gene expression.
Anastasia J. Lindahl +8 more
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Post‐translational modifications of proteins control many complex biological processes, including genome expression, chromatin dynamics, metabolism, and cell division. Histone protein acetylation and methylation have been extensively linked to the regulation of chromatin remodeling and gene expression.
Anastasia J. Lindahl +8 more
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Journal of Cardiovascular Translational Research
Myocardial infarction (MI) remains a leading cause of mortality, and although reperfusion therapy is essential for myocardial salvage, it often results in ischemia-reperfusion (I/R) injury, which contributes substantially to cardiomyocyte necrosis. Although the mechanisms of cardiomyocyte necrosis remain unclear, we identified ACSS2 as a key regulator ...
Xinhui Chen +7 more
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Myocardial infarction (MI) remains a leading cause of mortality, and although reperfusion therapy is essential for myocardial salvage, it often results in ischemia-reperfusion (I/R) injury, which contributes substantially to cardiomyocyte necrosis. Although the mechanisms of cardiomyocyte necrosis remain unclear, we identified ACSS2 as a key regulator ...
Xinhui Chen +7 more
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Archives of Microbiology, 2001
The hyperthermophilic, sulfate-reducing archaeon Archaeoglobus fulgidus strain 7324, rather than the type strain VC16, was found to grow on starch and sulfate as energy and carbon source. Fermentation products and enzyme activities were determined in starch-grown cells and compared to those of cells grown on lactate and sulfate.
A, Labes, P, Schönheit
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The hyperthermophilic, sulfate-reducing archaeon Archaeoglobus fulgidus strain 7324, rather than the type strain VC16, was found to grow on starch and sulfate as energy and carbon source. Fermentation products and enzyme activities were determined in starch-grown cells and compared to those of cells grown on lactate and sulfate.
A, Labes, P, Schönheit
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