Results 151 to 160 of about 199,012 (297)

From Bench to Bedside: Emerging Paradigms in CAR‐T Cell Therapy for Solid Malignancies

Advanced Science, EarlyView.
This review discusses emerging paradigms in CAR‐T cell therapy for solid tumors, emphasizing strategies to overcome therapeutic barriers through synthetic biology, immune engineering, and combinatorial approaches. It highlights advancements in logic gating, modulation of the immune microenvironment, and innovative cell designs, providing valuable ...
Yang Chen, Ran Ren, Lirong Yan, Yu Zhou, Ruokai Sun, Huicong Song, Hongfei Yan, Yongsheng Li   +7 more
wiley   +1 more source

Combination of HDAC inhibitor and PI3K inhibitor suppresses autophagy and induces apoptosis via cytoplasmic IκBα stabilization in p53-mutant diffuse large B-cell lymphoma. [PDF]

Cell Death Discov
Yao J, Li M, Jiang Y, Yao N, Liu Y, Lv L, Li Y, Huang J, Zha J, Xu B.   +9 more
europepmc   +1 more source

PREPARATION OF ACETATE RAYON BY THE ACETYLATION OF VISCOSE RAYON WITH ACETIC ANHYDRIDE VAPOR

, 1954
Ichiro Sakurada, Yasuyoshi Sakaguchi
openalex   +2 more sources

Detection of Acetylated and Non-Acetylated Histones in Chromatin [PDF]

Microscopy and Microanalysis, 2005
D O'Connell, Mark Wall, M Mulrooney, M Giffin, J Bertram, C Empey, J Ebesu   +6 more
openaire   +1 more source

Mechanical Cues Regulate Cargo Sorting and Export at the Golgi

Advanced Science, EarlyView.
A pathway is identified linking extracellular matrix stiffness to secretion via Src–FAK–AMPK–GBF1 signaling. Golgi‐localized GBF1 acts as a mechanotransducer whose phosphorylation controls post‐Golgi cargo sorting toward secretion or lysosomal degradation.
Greta Serafino, Stefania Forciniti, Edoardo Scarpa, Antonio Ranieri, Lucia Santorelli, Gabriella De Blasi, Sara Costantini, Eunjoo Jun Lee, Antonio Galeone, Alessia Calcagnì, Marinella Pirozzi, Loretta L. del Mercato, Rossella Venditti, Giovanni D'Angelo, Seetharaman Parashuraman, Tiziano Verri, Giuseppe Gigli, Elizabeth S. Sztul, Paolo Grumati, Loris Rizzello, Domenico Russo, Riccardo Rizzo   +21 more
wiley   +1 more source

Valemetostat-SAHA-Driven Acetylation of p53 via SET/TAF-Iβ Displacement and p300 Activation Modulates Cell Cycle Regulators in Pancreatic Cancer Cells. [PDF]

Biomedicines
Di Crosta M, Ragone FC, Benedetti R, D'Orazi G, Santarelli R, Gilardini Montani MS, Cirone M.   +6 more
europepmc   +1 more source

THE FIBROUS ACETYLATION OF VISCOSE RAYON WITH KETENE

, 1957
Yoshio Iwakura, Masahiko Takikawa, Ichiro Kanda   +2 more
openalex   +2 more sources

Disruption of Gut Microbiota‐Mediated De Novo NAD+ Synthesis Contributes to the Development of Polycystic Ovary Syndrome

Advanced Science, EarlyView.
This study demonstrates that patients with PCOS exhibit altered gut microbial profiles, and FMT from PCOS patients induces PCOS‐like symptoms in mice. Specifically, gut dysbiosis reduces 3‐HAA levels in the context of PCOS. Administration of 3‐HAA to mice alleviates PCOS by promoting de novo NAD+ synthesis.
Ke Chen, Huafeng Geng, Yang Zheng, Hongyang Xie, Rui Qin, Junyang Chen, Cong Ye   +6 more
wiley   +1 more source

Non-canonical dihydrolipoyl transacetylase promotes chemotherapy resistance via mitochondrial tetrahydrofolate signaling. [PDF]

Nat Commun
Hwang JS, Kang J, Kim J, Eun K, West S, Bacho HE, Avalos V, Shuff S, Shin DM, Saba NF, Magliocca KR, Qu CK, Fu H, Ramalingam SS, Ivanov AA, Hitosugi T, Kang S.   +16 more
europepmc   +1 more source

PREPARATION OF ACETATE RAYON BY THE ACETYLATION OF VISCOSE RAYON WITH ACETIC ANHYDLIDE VAPOR

, 1955
Ichiro Sakurada, Yasuyoshi Sakaguchi
openalex   +2 more sources