Results 171 to 180 of about 199,012 (297)

SOX2 drives esophageal squamous carcinoma by reprogramming lipid metabolism and histone acetylation landscape. [PDF]

open access: yesNat Commun
Wang Z   +16 more
europepmc   +1 more source

BHLHE40 Cooperates with GATA2/3 to Control Human Syncytiotrophoblast Lineage Differentiation

open access: yesAdvanced Science, EarlyView.
BHLHE40 interacts directly with GATA2 and GATA3 and co‐occupies genomic loci critical for STB differentiation and function. BHLHE40 also affects GATA2/3 binding at enhancer and promoter regions. Moreover, BHLHE40 is potentially involved in genome‐wide remodeling of H3K4me3 and H3K27ac chromatin landscapes through GATA2/3 recruitment, activating ...
Lijin Peng   +11 more
wiley   +1 more source

HOS15 together with PWR-HDA9 positively regulates dark-induced senescence in Arabidopsis. [PDF]

open access: yesPlant Signal Behav
Zareen S   +7 more
europepmc   +1 more source

Long Non‐Coding RNA IGFRIL Couples with PTBP1 to Destabilize IGFBP3 mRNA to Promote the IGF1R‐AKT‐mTOR Axis and Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
The limited understanding of IGFR pathway activation hinders its clinical application in HCC. Here, IGFRIL is identified as a novel non‐coding activator of the IGF1R, which recruits PTBP1 to destabilize IGFBP3 mRNA and activates IGF1R, and proposes IGFRIL as a novel actionable target for HCC patients.
Jing Zhang   +28 more
wiley   +1 more source

Disruption of histone acetylation homeostasis reveals multilayered chromatin regulation for transcriptional resiliency. [PDF]

open access: yesEpigenetics Chromatin
Venu V   +10 more
europepmc   +1 more source

Next‐Generation Piezoelectric Materials in Wearable and Implantable Devices for Continuous Physiological Monitoring

open access: yesAdvanced Science, EarlyView.
An analysis of literature trends and a historical overview of organic and inorganic piezoelectric materials, focusing on their structural diversity, functional mechanisms, and inherent characteristics. It then explores cutting‐edge developments in material synthesis, fabrication processes, and performance optimization, highlighting their applicability ...
Bangul Khan   +7 more
wiley   +1 more source

KAT5-mediated acetylation of PC4 facilitates DNA repair by promoting chromatin reorganization. [PDF]

open access: yesNucleic Acids Res
Agrawal A   +11 more
europepmc   +1 more source

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