Results 171 to 180 of about 374,029 (398)
Advanced Synthesis &Catalysis, EarlyView.Abstract Glycosyl furans represent versatile chiral platform molecules that can be readily accessed via the Garcia Gonzalez reaction. Herein, we report a dearomative, intramolecular bromoetherification of carbohydrate‐derived glycosyl furans to generate enantiopure 6‐bromo‐furo[3,2‐b]furans in up to 69% yield. The method employs N‐Br aromatic amides as
William J. Berkey +5 more
wiley +1 more source
Cell Reports, 2019 Summary: Neuronal activity-inducible gene transcription correlates with rapid and transient increases in histone acetylation at promoters and enhancers of activity-regulated genes.
Liang-Fu Chen +12 more
doaj
BMC GenomicsBackground The deep-sea cold seep zone is characterized by high pressure, low temperature, darkness, and oligotrophy. Vesicomyidae clams are the dominant species within this environment, often forming symbiotic relationships with chemosynthetic microbes.
Xue Kong +7 more
doaj +1 more source
Histone Deacetylases in Herpesvirus Replication and Virus-Stimulated Host Defense
Viruses, 2013 Emerging evidence highlights a critical role for protein acetylation during herpesvirus infection. As prominent modulators of protein acetylation, histone deacetylases (HDACs) are essential transcriptional and epigenetic regulators.
Ileana M. Cristea +3 more
doaj +1 more source
New class of compounds - variators - are reprogramming substrate specificity of H4K12Ac, H4K16Ac and H4K20Ac epigenetic marks reading bromodomain of BPTF protein [PDF]
arXiv, 2015 Previously reported [http://arxiv.org/abs/1506.06433] reprogramming of substrate specificity of H3K4Me3 epigenetic marks reading PHD domain of BPTF protein illustrates therapeutic potential of a new class of non-inhibitor small organic compounds - variators.
arxiv
Acetylation of Mitochondrial Proteins in the Heart: The Role of SIRT3
Frontiers in Physiology, 2018 A growing number of studies have demonstrated the role of post-translational modifications of proteins, particularly acetylation, in human diseases including neurodegenerative and cardiovascular diseases, diabetes, cancer, and in aging.
Rebecca M. Parodi‐Rullán +2 more
semanticscholar +1 more source
Advanced Sustainable Systems, EarlyView.Hydrogels made of chemically modified biopolymers are easy to prepare and cost‐effective, they have proven to be effective materials for the simultaneous removal of seven potentially toxic elements (PTEs) from ultrapure and real water samples. The cellulose‐based one seems the best for single treatments while the gelatine‐based one seems the most ...
Monica Rigoletto +6 more
wiley +1 more source
Nonparametric false discovery rate control for identifying simultaneous signals [PDF]
arXiv, 2015 It is frequently of interest to jointly analyze multiple sequences of multiple tests in order to identify simultaneous signals, defined as features tested in multiple studies whose test statistics are non-null in each. In many problems, however, the null distributions of the test statistics may be complicated or even unknown, and there do not currently
arxiv
Recent Advancements in Lung Cancer Metastasis Prevention Based on Nanostrategies
Advanced Science, EarlyView.Metastasis is the leading cause of death in patients with lung cancer. Nanomedicine can be used to prepare efficient drug delivery systems owing to their advantages and plays an important role in the synergistic antimetastasis of lung cancer. This comprehensive review summarizes the emerging nanostrategies against lung cancer metastasis based on the ...
Fan Xu +7 more
wiley +1 more source