Results 191 to 200 of about 191,770 (239)

Synthesis of an Enzyme‐Triggered Chitosan‐Based Drug Delivery System for Peri‐Implantitis Prevention

Chemistry – A European Journal, EarlyView.
ABSTRACT Dental implants have become a leading solution for tooth loss, yet bacterial infections remain a major complication. Antibacterial implant coatings are an important approach to reduce or prevent bacterial infections at the implant. Given the oral cavity's complex microbiome and the importance of some commensal bacteria, it is crucial to ...
Nelly Senze Nnane, Amit Gaikwad, Muhammad Imran Rahim, Andreas Winkel, Oliver Hergert, Till Beuerle, Meike Stiesch, Henning Menzel   +7 more
wiley   +1 more source

African swine fever virus DEAD-box helicase D1133L promotes OGG1-driven incision of genomic 8-oxoG via HDAC5 deacetylation. [PDF]

J Mol Cell Biol
Fan J, Yang J, Tian Z, Zhang X, Geng S, Luo J, Boldogh I, Zeng Q, Yin H, Guan G, Niu Q.   +10 more
europepmc   +1 more source

Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview

Chemistry – A European Journal, EarlyView.
The graphical abstract summarizes the review “Pd(II)‐Catalyzed Strategies for the β‐Arylation of α‐Amino Acids: An Overview”, highlighting representative Pd(II)‐catalyzed methods for the β‐arylation of α‐amino acids. Key mechanistic features, substrate diversity, and synthetic relevance of these transformations are showcased. Abstract Metal‐catalyzed C─
Davide Illuminati, Claudio Trapella, Vinicio Zanirato, Virginia Cristofori, Anna Fantinati   +4 more
wiley   +1 more source

Targeting the SIRT1-NAT10-GABABR1 Axis: A Novel Epitranscriptomic Approach to Mitigate Sevoflurane-Induced Cognitive Impairment in Aging. [PDF]

CNS Neurosci Ther
Xie X, Du W, Zhang Y, Zhang X.
europepmc   +1 more source

Porphyrin‐Geländer–Helical Conjugated Banister Type Porphyrin Dyads

Chemistry – A European Journal, EarlyView.
Porphyrin arrays go chiral–A porphyrin Geländer macrocycle represents the intriguing prototype architecture of helically chiral butadiyne‐linked porphyrin arrays. This study combines synthetic, spectroscopic, and computational methods to shed light on its structure, chiroptical properties, and tunability, highlighting its promise for advancing ...
Joël F. Keller, Adriano D'Addio, Marcel Mayor   +2 more
wiley   +1 more source

PolyP inhibits CobB deacetylase triggering a regulatory coupling to prevent DNA replication initiation. [PDF]

Nucleic Acids Res
Boguszewska E, Hirsz Z, Sroka M, Bury K, Chmura W, Strzałka A, Kołodziej M, Zakrzewska-Czerwińska J, Konieczny I.   +8 more
europepmc   +1 more source

Synthesis and Glycosidase Inhibition Studies of Novel Exoglycals Targeting GH3 Family Enzymes: Insights from Comparative Analysis with Macrolide Antibiotics

Chemistry – A European Journal, EarlyView.
A series of structurally diverse exoglycals was synthesized using a modified Julia‐olefination approach from sugar‐derived precursors. These glycosidase transition‐state mimics were further diversified via CuAAC chemistry to yield triazole‐conjugated analogues.
Elisa Ospanow, Oscar L. Alferez, David L. Jakeman   +2 more
wiley   +1 more source

The roles of post-translational modifications in the pathogenesis of RNA viruses: allies or adversaries? [PDF]

Front Microbiol
Shao T, Pei Z, Wang Y, Zhao Y, Fan H, Pan J.   +5 more
europepmc   +1 more source

It's a Gas: Bioconjugation With Vapor‐Phase Reagents

Chemistry – A European Journal, EarlyView.
Gaseous reagents are an emerging class of bioconjugation reagents that can offer alternative selectivity paradigms for the construction of precise bioconjugates. A variety of both inert and highly reactive gases have recently been developed for bioconjugation use.
Yuxuan Ding, Jun Ohata, Zachary T. Ball
wiley   +1 more source

BDH1 acetylation at K116 modulates milk fat production in dairy goats. [PDF]

J Anim Sci Biotechnol
Xiong T, Chen C, Gong X, Han C, Tian M, Luo J, Deng L, Loor JJ, Li C.   +8 more
europepmc   +1 more source