Results 231 to 240 of about 199,012 (297)

Temporal Stretch‐Induced Nuclear Mechanosensing Coordinates Early Chromatin Accessibility and Genome Protection

Advanced Science, EarlyView.
Cyclic stretching of fibroblasts triggers coordinated nuclear mechanosensing events, including calcium ion release, perinuclear actin assembly, emerin translocation, and H3K9me3 loss, increasing chromatin accessibility for specific genes related to mechanotransduction and repair.
Hye‐Won Shim, Ji‐Young Yoon, Hwalim Lee, Shanika Karunasagara, Cheng Ji Li, Yongdae Shin, Sukbum Hong, Dong‐Joon Lee, Jung‐Hwan Lee, Kam W. Leong, Hae‐Won Kim   +10 more
wiley   +1 more source

Will Stub1 Be the Next Target for Pulmonary Hypertension Therapy Development? [PDF]

Am J Respir Cell Mol Biol
Shen Y.
europepmc   +1 more source

Assessing the Nature of Human Brain‐Derived Extracellular Vesicles on Synaptic Activity Via the Development of an Air‐liquid Microfluidic Platform

Advanced Science, EarlyView.
This seminal study highlights the interwoven and tightly regulated functions of brain‐derived extracellular vesicles. Using microfluidics, proteomics, and AI‐based electric signal analyses of cortical brain explants, this work provides a useful resource dataset revealing the composition of human brain‐derived extracellular vesicles obtained from ...
Corentin Bernou, Yukiko Iwasaki, Willy Lutz, Glaucia Almeida, Emilie Béchard, François Delalande, Magali Rompais, Jules Bouget, Barbara Gorda, Chantal Cazevieille, Yonis Bare, Christine Carapito, Sophie Colomb, Gowrishankar Ganesh, Raphael Gaudin   +14 more
wiley   +1 more source

Chemical Studies of Histone Acetylation

, 1974
David Krieger, Robert Levine, R. B. Merrifield, Giorgio Vidali, Vincent G. Allfrey   +4 more
openalex   +1 more source

Photobiomodulation Strengthens Muscles via Its Dual Functions in Gut Microbiota

Advanced Science, EarlyView.
Non‐invasive photobiomodulation therapy (PBMT) enhances muscle endurance by rewiring the gut‐muscle axis. PBMT preserves gut epithelial integrity and enriches beneficial anaerobes, driving metabolites such as butyrate, spermidine, and L‐carnitine that supercharge mitochondrial energy in skeletal muscles.
Prabhat Upadhyay, Asmita Banstola, Brijesh Bhayana, Mei X. Wu   +3 more
wiley   +1 more source

Mitochondrial hyper-acetylation induced by an engineered acetyltransferase promotes cellular senescence. [PDF]

iScience
Shimazu T, Kataoka A, Suzuki T, Dohmae N, Shinkai Y.   +4 more
europepmc   +1 more source

Bioengineered Skin Grafts from Patient‐Derived Decellularized Extracellular Matrix and Autologous Cells for Personalized Regenerative

Advanced Science, EarlyView.
This study presents a patient‐specific skin model using autologous cells, decellularized dermal ECM, and keratin–alginate bioinks. The model supports cell compatibility, collagen deposition, and epidermal differentiation within a biomimetic ECM environment.
RaeHui Kang, Suyeon Shin, Yurim Choi, WonJun Jang, Soojin Park, Mi Kyung Lee, Hyun‐Jong Cho, Yu Shrike Zhang, Han‐Jun Kim, Bo Young Park, Junmin Lee   +10 more
wiley   +1 more source

SIRT1 retention in elongating spermatids interferes with histone displacement by counteracting MOF-dependent H4K16 acetylation. [PDF]

Front Cell Dev Biol
Porreca V, Chioccarelli T, Albano F, Nittoli V, Ricci G, Ambrosino C, Chianese R, Mele VG, Migliaccio A, Stornaiuolo M, Suglia A, Cobellis G, Manfrevola F.   +12 more
europepmc   +1 more source

Shifu‐Inspired Fungal Paper Yarns

Advanced Science, EarlyView.
Fungal chitin‐β‐glucan sheets, processed using Shifu techniques, yield yarns with tunable strength and mechanical properties matching or surpassing cotton and viscose. Chemical modification and hybridization routes enable further property control.
Anne Zhao, Mitchell P. Jones, Kathrin Weiland, Alexander Bismarck   +3 more
wiley   +1 more source

Development of a prognostic risk model for predicting biochemical recurrence-free survival in patients with prostate cancer based on lysine acetylation. [PDF]

Transl Androl Urol
Cao B, Chen H, Zhang L, Xiao F, Liu Q, Tang L, You T, Ouyang Q.   +7 more
europepmc   +1 more source