Results 41 to 50 of about 374,029 (398)
Relaxation in the glass-former acetyl salicylic acid studied by deuteron magnetic resonance and dielectric spectroscopy [PDF]
Phys. Rev. E 74, 021506 (2006), 2006 Supercooled liquid and glassy acetyl salicylic acid was studied using dielectric spectroscopy and deuteron relaxometry in a wide temperature range. The supercooled liquid is characterized by major deviations from thermally activated behavior. In the glass the secondary relaxation exhibits the typical features of a Johari-Goldstein process.
arxiv +1 more source
Erasers of histone acetylation: the histone deacetylase enzymes.
Cold Spring Harbor Perspectives in Biology, 2014 Histone deacetylases (HDACs) are enzymes that catalyze the removal of acetyl functional groups from the lysine residues of both histone and nonhistone proteins.
E. Seto, Minoru Yoshida
semanticscholar +1 more source
Acetylation Modification During Autophagy and Vascular Aging
Frontiers in Physiology, 2021 Vascular aging plays a pivotal role in the morbidity and mortality of elderly people. Decrease in autophagy leads to acceleration of vascular aging, while increase in autophagy leads to deceleration of vascular aging. And emerging evidence indicates that
Jiaxing Sun +8 more
doaj +1 more source
Simulations Suggest Pharmacological Methods for Rescuing Long-Term Potentiation [PDF]
Journal of Theoretical Biology, 7 Nov 2014, pp. 243-250, 2014 Congenital cognitive dysfunctions are frequently due to deficits in molecular pathways that underlie synaptic plasticity. For example, Rubinstein-Taybi syndrome (RTS) is due to a mutation in cbp, encoding the histone acetyltransferase CREB-binding protein (CBP).
arxiv +1 more source
Palladium-catalyzed acetylation of arenes. [PDF]
, 2014 A simple method for the preparation of aryl methyl ketones is reported. The transformation involves the Pd-catalyzed coupling of an acyl anion equivalent, acetyltrimethylsilane, with aryl bromides to afford the corresponding acetylated arenes in ...
Garg, Neil K, Ramgren, Stephen D
core +1 more source
Acetylation, Deacetylation and Acyltransfer [PDF]
Environmental Health Perspectives, 1983 N-Substituted aromatic compounds can be metabolized in most species to N-acetylated derivatives that are themselves subject to further enzymatic transformations, including hydrolysis and N,O-acyltransfer. These proceses can either potentiate or ameliorate the biological responses to these N-substituted derivatives. Decreasing the levels of metabolites,
Irene B. Glowinski, Charles M. King
openaire +3 more sources
Lysine acetylation regulates the interaction between proteins and membranes
Nature Communications, 2021 Lysine acetylation regulates the function of soluble proteins in vivo, yet it remains largely unexplored whether lysine acetylation regulates the function of membrane proteins.
Alan K. Okada +14 more
doaj +1 more source
Effects of α-tubulin acetylation on microtubule structure and stability
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Microtubules are polymers of αβ-tubulin that play important roles in the cell. Regulation of their dynamics is critical for function and includes the posttranslational modification of tubulin.
L. Eshun-Wilson +9 more
semanticscholar +1 more source
Histone acetylation and the role of histone deacetylases in normal cyclic endometrium
Reproductive Biology and Endocrinology, 2020 Histone acetylation is a critical epigenetic modification that changes chromatin architecture and regulates gene expression by opening or closing the chromatin structure. It plays an essential role in cell cycle progression and differentiation. The human
Palak Gujral +3 more
semanticscholar +1 more source
A moonlighting metabolic protein influences repair at DNA double-stranded breaks. [PDF]
, 2015 Catalytically active proteins with divergent dual functions are often described as 'moonlighting'. In this work we characterize a new, chromatin-based function of Lys20, a moonlighting protein that is well known for its role in metabolism.
Aris, John P +2 more
core +1 more source