Results 21 to 30 of about 198,075 (255)
mSystems, 2016 N ε-Lysine acetylation has been recognized as a ubiquitous regulatory posttranslational modification that influences a variety of important biological processes in eukaryotic cells.
Valerie J. Carabetta +4 more
doaj +1 more source
Acetylation Goes Global: The Emergence of Acetylation Biology [PDF]
Science Signaling, 2009 Proteomic analysis shows protein acetylation to be more prevalent than previously appreciated.
Kristi L, Norris +2 more
openaire +2 more sources
Acetylation of GATA4 on Lysine Residue K313 Promotes Osteoblastic Cells Growth
Cellular Physiology and Biochemistry, 2018 Background/Aims: GATA4, a protein related to osteoblast differentiation and mineralization, whose acetylation is essential for cardiac defects. Here, we aimed to explore the functional impacts of GATA4 acetylation on osteoporosis (OS).
Wenjun You, Lijuan Song, Kun Wang
doaj +1 more source
Cells, 2022 Mitochondrial protein acetylation is associated with a host of diseases including cancer, Alzheimer’s, and metabolic syndrome. Deciphering the mechanisms regarding how protein acetylation contributes to disease pathologies remains difficult due to the ...
Courtney D. McGinnis +4 more
doaj +1 more source
Acetylation dynamics and stoichiometry in Saccharomyces cerevisiae
Molecular Systems Biology, 2014 Lysine acetylation is a frequently occurring posttranslational modification; however, little is known about the origin and regulation of most sites.
Brian T. Weinert +7 more
doaj +1 more source
The interaction of canonical Wnt/β-catenin signaling with protein lysine acetylation
Cellular & Molecular Biology Letters, 2022 Canonical Wnt/β-catenin signaling is a complex cell-communication mechanism that has a central role in the progression of various cancers. The cellular factors that participate in the regulation of this signaling are still not fully elucidated.
Hongjuan You +6 more
doaj +1 more source
Cell Reports, 2017 Summary: Acetyl coenzyme A (AcCoA), a key intermediate in mitochondrial metabolism, N-acetylates lysine residues, disrupting and, in some cases, regulating protein function.
Andrew M. James +6 more
doaj +1 more source
Protein Acetylation/Deacetylation: A Potential Strategy for Fungal Infection Control
Frontiers in Microbiology, 2020 Protein acetylation is a universal post-translational modification that fine-tunes the major cellular processes of many life forms. Although the mechanisms regulating protein acetylation have not been fully elucidated, this modification is finely tuned ...
Junzhu Chen +3 more
doaj +1 more source
Engineering Microbiology, 2022 Lactate is an important bulk chemical with widespread applications and a major byproduct of other chemicals bioprocess in microbial fermentation. Lactate dehydrogenase A (LdhA) catalyzes the synthesis of lactate from pyruvate.
Min Liu +7 more
doaj +1 more source
Acetylation, Deacetylation and Acyltransfer [PDF]
Environmental Health Perspectives, 1983 N-Substituted aromatic compounds can be metabolized in most species to N-acetylated derivatives that are themselves subject to further enzymatic transformations, including hydrolysis and N,O-acyltransfer. These proceses can either potentiate or ameliorate the biological responses to these N-substituted derivatives. Decreasing the levels of metabolites,
C M, King, I B, Glowinski
openaire +2 more sources