Results 11 to 20 of about 337,770 (296)

Acetylation of Raw Cotton for Oil Spill Cleanup Application: an FTIR and 13-C MAS NMR Spectroscopic Investigation [PDF]

open access: yes, 2004
Fourier transform infrared (FTIR) and 13C MAS NMR spectroscopy have been used to investigate the acetylation of raw cotton samples with acetic anhydride without solvents in the presence of different amounts of 4-dimethylaminopyridine (DMAP) catalyst ...
Adebajo, Moses, Frost, Raymond
core   +2 more sources

Activation of AMP-activated protein kinase by metformin induces protein acetylation in prostate and ovarian cancer cells [PDF]

open access: yes, 2016
AMP-activated protein kinase (AMPK) is an energy sensor and master regulator of metabolism. AMPK functions as a fuel gauge monitoring systemic and cellular energy status.
Galdieri, Luciano   +3 more
core   +2 more sources

Androgen receptor acetylation governs trans activation and MEKK1-induced apoptosis without affecting in vitro sumoylation and trans-repression function [PDF]

open access: yes, 2002
This work was supported by grants from the NIH (R01CA86072 to R.G.P. and R01CA72038-01 to S.A.W.F.) and The Susan Komen Breast Cancer Foundation (to R.G.P.). R.T.H. and E.J. were supported by the Medical Research Council. Y.-G.Y.
Chang, Chawnshang   +13 more
core   +1 more source

N-terminal acetylation can stabilize proteins independent of their ubiquitination

open access: yesScientific Reports, 2023
The majority of proteins in mammalian cells are modified by covalent attachment of an acetyl-group to the N-terminus (Nt-acetylation). Paradoxically, Nt-acetylation has been suggested to inhibit as well as to promote substrate degradation.
Bert van de Kooij   +6 more
doaj   +1 more source

Acetylation of GATA4 on Lysine Residue K313 Promotes Osteoblastic Cells Growth

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: GATA4, a protein related to osteoblast differentiation and mineralization, whose acetylation is essential for cardiac defects. Here, we aimed to explore the functional impacts of GATA4 acetylation on osteoporosis (OS).
Wenjun You, Lijuan Song, Kun Wang
doaj   +1 more source

Identification and Functional Characterization of N-Terminally Acetylated Proteins in Drosophila melanogaster [PDF]

open access: yes, 2009
Protein modifications play a major role for most biological processes in living organisms. Amino-terminal acetylation of proteins is a common modification found throughout the tree of life: the N-terminus of a nascent polypeptide chain becomes co ...
Goetze, S   +17 more
core   +3 more sources

Lysine acetylation decreases enzyme activity and protein level of Escherichia coli lactate dehydrogenase

open access: yesEngineering Microbiology, 2022
Lactate is an important bulk chemical with widespread applications and a major byproduct of other chemicals bioprocess in microbial fermentation. Lactate dehydrogenase A (LdhA) catalyzes the synthesis of lactate from pyruvate.
Min Liu   +7 more
doaj   +1 more source

Acetylation dynamics and stoichiometry in Saccharomyces cerevisiae

open access: yesMolecular Systems Biology, 2014
Lysine acetylation is a frequently occurring posttranslational modification; however, little is known about the origin and regulation of most sites.
Brian T. Weinert   +7 more
doaj   +1 more source

Biochemical Mechanisms of Sirtuin-Directed Protein Acylation in Hepatic Pathologies of Mitochondrial Dysfunction

open access: yesCells, 2022
Mitochondrial protein acetylation is associated with a host of diseases including cancer, Alzheimer’s, and metabolic syndrome. Deciphering the mechanisms regarding how protein acetylation contributes to disease pathologies remains difficult due to the ...
Courtney D. McGinnis   +4 more
doaj   +1 more source

Non-enzymatic N-acetylation of Lysine Residues by AcetylCoA Often Occurs via a Proximal S-acetylated Thiol Intermediate Sensitive to Glyoxalase II

open access: yesCell Reports, 2017
Summary: Acetyl coenzyme A (AcCoA), a key intermediate in mitochondrial metabolism, N-acetylates lysine residues, disrupting and, in some cases, regulating protein function.
Andrew M. James   +6 more
doaj   +1 more source

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