Results 41 to 50 of about 230,380 (304)

Skeletal muscle alpha actin acetylation enhances myosin binding and increases calcium sensitivity

Biophysical Reports
Skeletal muscle alpha actin (ACTA1) is important for muscle contraction and relaxation, with historical studies focused on ACTA1 mutations in muscle dysfunction.
Samantha S. Romanick, Luis Godoy, Adrian Lopez, Allison Matsumura, Kiana Boc, Travis J. Stewart, Josh E. Baker, Bradley S. Ferguson   +7 more
doaj   +1 more source

Protein acetylation in archaea, bacteria, and eukaryotes

, 2010
Proteins can be acetylated at the alpha-amino group of the N-terminal amino acid (methionine or the penultimate amino acid after methionine removal) or at the epsilon-amino group of internal lysines.
Soppa, Jörg (Prof. Dr.)
core   +1 more source

Acetylation of WRN protein regulates its stability by inhibiting ubiquitination. [PDF]

PLoS ONE, 2010
WRN is a multi-functional protein involving DNA replication, recombination and repair. WRN acetylation has been demonstrated playing an important role in response to DNA damage.
Kai Li, Rui Wang, Enerlyn Lozada, Wei Fan, David K Orren, Jianyuan Luo   +5 more
doaj   +1 more source

Acetylation site specificities of lysine deacetylase inhibitors in human cells

, 2015
This work was supported by the Hallas Møller Investigator grant from the Novo Nordisk Foundation to C.C. S.A.W. and P.B. were supported by individual postdoctoral grants from the Danish Research Council (FSS: 10-085134, FSS: 12-12610). C.C.
Sebastian A Wagner, Jensen, Lars J., Jensen, Lars J, Chunaram Choudhary, Qi, Yun, Sonia Lain, Wagner, Sebastian A, Weinert, Brian T., James E Bradner, McCarthy, Anna R, Mann, Matthias, Yasuyuki Miyake, Westwood, Nicholas J, Schölz, Christian, Wagner, Sebastian A., Choudhary, Chunaram, Choudhary, Chuna Ram, Matthias, Patrick, Bradner, James E, Anna R McCarthy, Werner Streicher, Weinert, Brian Tate, Lain, Sonia, Bradner, James E., Matthias Mann, Nicholas J Westwood, Lars J Jensen, Jürgen Cox, Westwood, Nicholas James, Brian T Weinert, Cox, Jürgen, Christian Schölz, Streicher, Werner, McCarthy, Anna Rose, Lain, Sonya, Beli, Petra, Qi, Jun, Petra Beli, Jun Qi, Miyake, Yasuyuki, Patrick Matthias   +40 more
core   +1 more source

How important is the N-terminal acetylation of alpha-synuclein for its function and aggregation into amyloids?

Frontiers in Neuroscience, 2022
N-α-acetylation is a frequently occurring post-translational modification in eukaryotic proteins. It has manifold physiological consequences on the regulation and function of several proteins, with emerging studies suggesting that it is a global ...
Aditya Iyer, Arshdeep Sidhu, Vinod Subramaniam   +2 more
doaj   +1 more source

Progress of Acetylation Modification in Plants

Agronomy
Protein acetylation, a conserved post-translational modification, is collaboratively catalyzed by acetyltransferases and deacetylases and is widespread in plants.
Ruiqi Li, Xuezhong Li, Ying He, Xiaoyuan Chen, Jing Li, Chuxiong Zhuang   +5 more
doaj   +1 more source

Androgen receptor acetylation governs trans activation and MEKK1-induced apoptosis without affecting in vitro sumoylation and trans-repression function

, 2014
This work was supported by grants from the NIH (R01CA86072 to R.G.P. and R01CA72038-01 to S.A.W.F.) and The Susan Komen Breast Cancer Foundation (to R.G.P.). R.T.H. and E.J. were supported by the Medical Research Council. Y.-G.Y.
Wang, Jian, Pestell, RG0, Fuqua, Suzanne A W, Wang, Chenguang, Yeung, YG, Hopp, Torsten, Jaffray, E, Chang, Chawnshang, Fu, Maofu, Sakamaki, Toshiyuki, Janne, OA, Zhang, Xueping, Hay, Ronald Thomas, Palvimo, Jorma J   +13 more
core   +1 more source

Highly regioselective surface acetylation of cellulose and shaped cellulose constructs in the gas-phase

, 2021
Gas-phase acylation of cellulose is an attractive method for modifying the surface properties of cellulosics. However, little is known concerning the regioselectivity of the chemistry, in terms of which cellulose positions are preferentially acylated and
Daniel, Rico del Cerro, Tetyana, Koso, Ilkka, Kilpeläinen, Marco, Beaumont, Alistair, King, Samuel, Eyley, Wim, Thielemans, Blaise, Tardy, Orlando, Rojas   +8 more
core   +1 more source

Redox state and the sirtuin deacetylases are major factors that regulate the acetylation status of the stress protein NQO1

Frontiers in Pharmacology, 2022
The stress induced protein NQO1 can participate in a wide range of biological pathways which are dependent upon the interaction of NQO1 with protein targets.
David Siegel, Peter S. Harris, Cole R. Michel, Cole R. Michel, Rafael de Cabo, Kristofer S. Fritz, David Ross   +6 more
doaj   +1 more source

Influence of N^ε-Lysine Acetylation on the Formation of Protein Aggregates and Antibiotic Persistence in E. coli

Molecules
Numerous studies indicate that reversible Nε-lysine acetylation in bacteria may play a key role in the regulation of metabolic processes, transcription and translation, biofilm formation, virulence, and drug resistance.
Karolina Stojowska-Swędrzyńska, Dorota Kuczyńska-Wiśnik, Ewa Laskowska   +2 more
doaj   +1 more source