Results 71 to 80 of about 204,757 (287)

Hierarchical Twist: Chirality Across Scales in Cellulose Cholesterics

open access: yesAdvanced Optical Materials, EarlyView.
Hierarchical left‐ and right‐handed chiral nematic structures are observed in a solvent‐free thermotropic cellulose derivative. Free‐standing films show hierarchical twisted structures whose pitches respond differently to uniaxial strain: left‐handed pitches increase, ones decrease.
N. Monge   +7 more
wiley   +1 more source

Histone Deacetylases in Herpesvirus Replication and Virus-Stimulated Host Defense

open access: yesViruses, 2013
Emerging evidence highlights a critical role for protein acetylation during herpesvirus infection. As prominent modulators of protein acetylation, histone deacetylases (HDACs) are essential transcriptional and epigenetic regulators.
Ileana M. Cristea   +3 more
doaj   +1 more source

Structural Colors from Ultrathin Lignin Films

open access: yesAdvanced Optical Materials, EarlyView.
Thickness‐dependent structural colors in ultrathin lignin films generate a full visible palette, tuned simply by solution concentration and spin speed. Abstract Structural colors offer a sustainable alternative to toxic pigments and dyes, yet their realization from lignin, the most abundant aromatic biopolymer, has remained elusive.
Bang An   +6 more
wiley   +1 more source

Exploring the Uncharted Indolizine Chemical Space: Construction of 5‐Acylindolizines via a Domino Aldol–Vinylogous Aldol Process

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
A domino aldol condensation–intramolecular vinylogous aldol condensation process was implemented for the first time to enable access to a wide range of novel 5‐acylated indolizines with a hydrogen, an alkyl, an aryl, or an alkoxy moiety at the C7 site.
Dohui Ku, Sunhee Lee, Ikyon Kim
wiley   +1 more source

Asymmetric Synthesis of Atropisomeric Amines via Transaminase‐Catalyzed Dynamic Kinetic Resolution

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
A dynamic kinetic resolution approach is developed for the atroposelective synthesis of heterobiaryl primary amines. Using transaminases and leveraging Lewis acid‐base interactions to induce racemization, a variety of axially chiral primary amines are produced in high yields and enantioselectivities.
Juan M. Coto‐Cid   +8 more
wiley   +1 more source

Smart REASSURED Sensors via Machine‐Augmented Printable On‐Paper Arrays

open access: yesAdvanced Sensor Research, EarlyView.
This perspective highlights the emerging role of pattern‐recognition, printable on‐paper sensor arrays for intelligent PoC diagnostics. It discusses how paper's inherent limitations can be overcome through surface modification and scalable printing, and how machine‐learning analysis of cross‐reactive arrays enables multiplexed, low‐cost, and REASSURED ...
Naimeh Naseri, Saba Ranjbar
wiley   +1 more source

Acetylation phenotype in squamous cell lung cancer

open access: yesJKS (Jurnal Kedokteran Syiah Kuala), 2009
Abstrak.   Risiko  kanker dipengaruhi   oleh   faktor   host dan lingkungan.    Bahan  dari lingkungan   yang   banyak menyebabkan   kanker   paru-paru   adalah   metabolite   dalam  asap   rokok,    Squamous    sel   kanker   paru-paru merupakan   jenis 
Mulyadi Mulyadi
doaj  

Phase‐Separation of YAP Mediates AJUBA Super Enhancer Activation to Promote Aberrant Mitosis in Breast Cancer

open access: yesAdvanced Science, EarlyView.
YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang   +8 more
wiley   +1 more source

Binding of the histone chaperone ASF1 to the CBP bromodomain promotes histone acetylation [PDF]

open access: bronze, 2014
Chandrima Das   +7 more
openalex   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

open access: yesAdvanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang   +16 more
wiley   +1 more source

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