Revisiting the Endocytosis of the M2 Muscarinic Acetylcholine Receptor
The agonist-induced endocytosis of the muscarinic acetylcholine receptor M2 is different from that of the other members of the muscarinic receptor family.
Wymke Ockenga, Ritva Tikkanen
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The inferior colliculus processes nearly all ascending auditory information. Most collicular cells respond to sound, and for a majority of these cells, the responses can be modulated by acetylcholine (ACh). The cholinergic effects are varied and, for the
William A. Noftz +5 more
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The influence of non-neuronal cells on catecholamine and acetylcholine synthesis and accumulation in cultures of dissociated sympathetic neurons [PDF]
The effects of several non-neuronal cell types on neurotransmitter synthesis in cultures of dissociated sympathetic neurons from the new-born rat were studied.
Chun, Linda L. Y., Patterson, Paul H.
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The action of atropine and acetylcholine on the pace maker ganglion cells of limulus heart [PDF]
On the median nerve trunk-heart muscle preparation of Limulus the authors studied the effects of atropine and acetylcholine upon the pace maker ganglion cells.
Hukuhara, Takesi +2 more
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Transient receptor potential canonical type 3 channels control the vascular contractility of mouse mesenteric arteries [PDF]
Transient receptor potential canonical type 3 (TRPC3) channels are non-selective cation channels and regulate intracellular Ca2+ concentration. We examined the role of TRPC3 channels in agonist-, membrane depolarization (high K+)-, and mechanical ...
Abramowitz, Joel +6 more
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Effects of different sugammadex doses on the train of four ratio recovery progression during rocuronium induced neuromuscular blockade in the rat phrenic nerve hemidiaphragm [PDF]
Background In this study, we used an ex-vivo model to investigate the recovery pattern of both the train-of-four (TOF) ratio and first twitch tension of TOF (T1), and determined their relationship during recovery from rocuronium-induced neuromuscular ...
Yong Beom Kim +5 more
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Differential sensitivity of basal and acetylcholine-induced activity of nitric oxide to blockade by asymmetric dimethylarginine (ADMA) in the rat aorta [PDF]
<b>Background and purpose</b>: Previous work has shown that NG-monomethyl-l-arginine (l-NMMA) paradoxically inhibits basal, but not ACh-stimulated activity of nitric oxide in rat aorta.
Archer +29 more
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Exercise training and losartan improve endothelial function in heart failure rats by different mechanisms [PDF]
Objectives. To investigate the mechanisms of losartan- and exercise training-induced improvements on endothelial dysfunction in heart failure. Design. Sprague-Dawley rats subjected to left coronary artery ligation inducing myocardial infarction and heart
Crozier I +5 more
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The neurotransmitter acetylcholine influences how male finches perform courtship songs by acting on a region of the premotor cortex called HVC.
Erin M Wall, Sarah C Woolley
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Acetylcholine (ACh) can act on pre- and post-synaptic muscarinic receptors (mAChR) in the cortex to influence a myriad of cognitive processes. Two functionally-distinct regions of the prefrontal cortex—the lateral prefrontal cortex (LPFC) and the ...
Alexandra Tsolias +2 more
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