Results 31 to 40 of about 155,024 (264)

Involvement of Acetylcholine Receptors in Cholinergic Pathway-Mediated Protection Against Autoimmune Diabetes

Frontiers in Immunology, 2019
Type I diabetes (T1D) is a T cell-driven autoimmune disease that results in the killing of pancreatic β-cells and, consequently, loss of insulin production.
Maria J. Fernández-Cabezudo, Junu A. George, Ghada Bashir, Yassir A. Mohamed, Alreem Al-Mansori, Mohammed M. Qureshi, Dietrich E. Lorke, Georg Petroianu, Basel K. al-Ramadi, Basel K. al-Ramadi   +9 more
doaj   +1 more source

Nerve Growth Factor: A Dual Activator of Noradrenergic and Cholinergic Systems of the Rat Ovary

Frontiers in Endocrinology, 2021
The functioning of the ovary is influenced by the autonomic system (sympathetic and cholinergic intraovarian system) which contributes to the regulation of steroid secretion, follicular development, and ovulation.
Agustin Benitez, Raul Riquelme, Miguel del Campo, Camila Araya, Hernan E. Lara   +4 more
doaj   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

Interrogating stonefish venom: small molecules present in envenomation caused by Synanceia spp.

FEBS Open Bio
The stonefish Synanceia verrucosa and Synanceia horrida are arguably the most venomous fish species on earth and the culprits of severe stings in humans globally.
Silvia Luiza Saggiomo, Steve Peigneur, Jan Tytgat, Norelle L. Daly, David Thomas Wilson   +4 more
doaj   +1 more source

Effects of Intranasal Orexin-A (Hypocretin-1) Administration on Neuronal Activation, Neurochemistry, and Attention in Aged Rats

Frontiers in Aging Neuroscience, 2020
Cognitive function represents a key determinative factor for independent functioning among the elderly, especially among those with age-related cognitive disorders.
Coleman B. Calva, Habiba Fayyaz, Jim R. Fadel   +2 more
doaj   +1 more source

Enzyme‐Loaded Fe3+‐Modified Polydopamine Microparticles: Bioreactor Systems for Operating Biocatalytic Cascades, Enantioselective Transformations and Sensor Applications

Advanced Functional Materials, EarlyView.
Enzyme‐loaded Fe3+‐modified polydopamine microparticles (Fe3+‐PD) act as hybrid biocatalytic frameworks demonstrating NADH peroxidase‐mimic catalytic activities, operation of biocatalytic cascades in confined media, and enantioselective oxidation of D/L‐DOPA. ABSTRACT We report on the synthesis of Fe3+‐modified porous polydopamine microparticles acting
Liubing Kong, Sérgio R. S. Veloso, Yichen Han, Jianghe Zhao, Vitaly Gutkin, Ofir Tirosh, Itamar Willner   +6 more
wiley   +1 more source

Myasthenia Gravis Masquerading as an Idiopathic Unilateral Facial Paralysis (Bell's Palsy)—A Very Rare and Unique Clinical Find

Frontiers in Neurology, 2020
Myasthenia gravis (MG) is an uncommon autoimmune neuromuscular junction disorder manifesting as fluctuating weakness of skeletal muscles. To add to its repertoire of mimicking a wide range of neurological disorders, the present case report is, to the ...
Marwa Elnazeir, Siddharth Narayanan, Pradeepthi Badugu, Abid Hussain, Tamour Tareen, Alexi R. Hernandez, Wei Liu, Adriana E. Palade, Martin E. Brown   +8 more
doaj   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Acetylcholine-acetylcholine esterase system in the stomach of different-aged piglets

RUDN Journal of Agronomy and Animal Industries, 2010
The paper presents results of the researches on acetylcholine-acetylcholine esterase system's formation in the stomach of piglets at an age of 1, 10, 21, 30, 60, 120 days.
N G Ignatyev, D P Mishina
doaj  

The regulatory action of acetylcholine and its receptors on B4 and C4 leukotriene formation in the porcine endometrium after experimental inflammogenic Escherichia coli infection

Journal of Veterinary Research
Endometritis is a very common pathology in animals which changes endometrial leukotriene (LT) formation and muscarinic 2 and 3 receptor subtypes (M2R/M3R) and α-7 nicotinic acetylcholine (ACh) receptor (α-7 nAChR) expression patterns.
Jana Barbara, Całka Jarosław, Bulc Michał, Kawka Dominika   +3 more
doaj   +1 more source